Response of supraoptic magnocellular neurons to stimulation of forebrain alpha-adrenoceptors.

Abstract:

:Effects of alpha-adrenoceptor agents on electrophysiologically and immunohistochemically identified supraoptic nucleus (SON) vasopressin (VP) units were investigated by intracarotid infusion. Clonidine, an alpha 2-adrenoceptor agonist always excited SON units and alpha 2-adrenoceptor antagonists consistently inhibited them. alpha 1-Adrenoceptor agents produced inconsistent responses. The results implicate forebrain alpha 2-adrenergic receptors in the excitation of SON VP neurons.

journal_name

Brain Res

journal_title

Brain research

authors

Mitchell LD,Callahan MF,Wilkin LD,Johnson AK

doi

10.1016/0006-8993(86)91526-x

subject

Has Abstract

pub_date

1986-12-10 00:00:00

pages

346-51

issue

2

eissn

0006-8993

issn

1872-6240

pii

0006-8993(86)91526-X

journal_volume

399

pub_type

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