Reversible blockade of PGO waves and concomitant modifications of thalamic unit activity in chronic cats.

Abstract:

:The reversible blockade of geniculate PGO waves was carried out by localized cooling of the ponto-geniculate pathways during paradoxical sleep in chronic cats. In parallel, long-term recordings of unit activity were performed in non-specific visuooculomotor thalamic structures where no PGO waves occurred. Blockade of geniculate PGO waves is concomitant with a preferential modification of the phasic discharge of the unit activity (i.e. time-locked with rapid eye movements) when compared to the tonic discharge (i.e. without rapid eye movements). These results suggest that pontine generators of PGO waves could act upon every neuron of the central nervous system. The significance of such an extensive ascending system, the blockade of which does not interrupt paradoxical sleep episodes, still remains puzzling.

journal_name

Brain Res

journal_title

Brain research

authors

Laurent JP,Rondouin G,Benita M,Jouvet M

doi

10.1016/0006-8993(77)90341-9

subject

Has Abstract

pub_date

1977-12-02 00:00:00

pages

305-22

issue

2

eissn

0006-8993

issn

1872-6240

pii

0006-8993(77)90341-9

journal_volume

137

pub_type

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