Adrenaline concentration and turnover in the arcuate nucleus and median eminence during the critical period in the rat.

Abstract:

:Previous work has shown a relatively high turnover of adrenaline in the mediobasal hypothalamus during the critical period (15.00-17.00 h) of the proestrous rat. We now report that this high level of adrenergic activity can be detected in the median eminence (turnover rate 1.62 +/- 0.36 pg/micrograms protein/h) rather than the arcuate nucleus (turnover rate 0.18 +/- 0.32 pg/micrograms protein/h). In addition the median eminence was isolated as medial and lateral components and determination of catecholamine concentrations revealed a greater proportion of adrenaline (A) (59%) in the lateral median eminence whereas a larger proportion of dopamine (60%) was found in medial median eminence.

journal_name

Brain Res

journal_title

Brain research

authors

Sheaves R,Warburton E,Laynes R,Mackinnon P

doi

10.1016/0006-8993(84)90307-x

subject

Has Abstract

pub_date

1984-12-10 00:00:00

pages

326-9

issue

2

eissn

0006-8993

issn

1872-6240

pii

0006-8993(84)90307-X

journal_volume

323

pub_type

杂志文章
  • Demonstration of calcitonin gene-related peptide immunoreactive axons contacting dynorphin A(1-8) immunoreactive spinal neurons in a rat model of peripheral inflammation and hyperalgesia.

    abstract::In a rat model of peripheral inflammation and hyperalgesia, dynorphin A(1-8)-like immunoreactive (DYN-LIr) spinal neurons were examined for contacts from calcitonin gene-related peptide-like immunoreactive (CGRP-LIr) varicosities using a double-label PAP method. Ipsilateral to the inflammation, CGRP-LIr varicosities c...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(88)90213-2

    authors: Takahashi O,Traub RJ,Ruda MA

    更新日期:1988-12-13 00:00:00

  • Ectopic discharges and adrenergic sensitivity of sensory neurons after spinal nerve injury.

    abstract::At various times after spinal nerve injury, dorsal root ganglia (DRGs) from injured segments were removed with attached dorsal roots and spinal nerves. In an in vitro recording chamber, spontaneously active units were recorded from teased dorsal root fascicles. Sustained spontaneous activity could first be recorded at...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(99)02165-4

    authors: Liu X,Chung K,Chung JM

    更新日期:1999-12-04 00:00:00

  • Pontine respiratory neurons in anesthetized cats.

    abstract::The pontine respiratory neurons (PRG) in the 'pneumotaxic centre' have been hypothesized to contribute to phase-switching of neural respiratory activity, especially in terminating inspiration. To define the neural elements involved in phase-switching, we recorded respiratory neurons extra- and intracellularly in anest...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(94)91025-1

    authors: Dick TE,Bellingham MC,Richter DW

    更新日期:1994-02-14 00:00:00

  • Brain damage in a mouse model of global cerebral ischemia. Effect of NMDA receptor blockade.

    abstract::The importance of particular genes in neuronal death following global cerebral ischemia can readily be studied in genetically modified mice provided a reliable model of ischemia is available. For that purpose, we developed a mouse model of global cerebral ischemia that induces consistent damage to different regions of...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(03)03014-2

    authors: Olsson T,Wieloch T,Smith ML

    更新日期:2003-08-29 00:00:00

  • Central and peripheral metabolism of 5 alpha-dihydrotestosterone in the male Japanese quail: biochemical characterization and relationship with reproductive behavior.

    abstract::An in vitro radioenzymatic assay and purification procedure by thin-layer chromatography were used to study the metabolism of dihydrotestosterone (DHT) into 3 alpha- and 3 beta-androstanediols by the brain and cloacal gland of Japanese quail. Kinetic studies showed that these 2 metabolites are produced in a linear fas...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(87)91280-7

    authors: Deviche P,Delville Y,Balthazart J

    更新日期:1987-09-22 00:00:00

  • Functional significance of projection from the cerebellar nuclei to the motor cortex in the cat.

    abstract::The functional organization of projections from the cerebellar subcortical nuclei to the motor cortex through the nucleus ventralis lateralis (VL) of the thalamus was studied using tungsten microelectrodes for stimulation and recordings in acute and chronic cats. The following results were obtained. (1) Microstimulati...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(75)90510-7

    authors: Asanuma H,Hunsperger RW

    更新日期:1975-11-07 00:00:00

  • DARPP-32 and CREB are present in type 2 iodothyronine deiodinase-producing tanycytes: implications for the regulation of type 2 deiodinase activity.

    abstract::Type 2 iodothyronine deiodinase, an enzyme involved in the conversion of thyroxin to the biologically active 3,5, 3'-triiodothyronine, is highly concentrated in a group of specialized ependymal cells, tanycytes, lining the wall and floor of the third ventricle. As this distribution is highly reminiscent of the distrib...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(00)02105-3

    authors: Fekete C,Mihály E,Herscovici S,Salas J,Tu H,Larsen PR,Lechan RM

    更新日期:2000-04-17 00:00:00

  • Maternal alcoholism and neonatal hypoxia-ischemia: Neuroprotection by stilbenoid polyphenols.

    abstract::The impact of maternal nutrition on neurodevelopment and neonatal neuroprotection is a research topic with increasing interest. Maternal diet can also have deleterious effects on fetal brain development. Fetal exposure to alcohol is responsible for poor neonatal global development, and may increase brain vulnerability...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2020.146798

    authors: Dumont U,Sanchez S,Olivier B,Chateil JF,Deffieux D,Quideau S,Pellerin L,Beauvieux MC,Bouzier-Sore AK,Roumes H

    更新日期:2020-07-01 00:00:00

  • Influence of non-neuronal cells on regeneration of the rat sciatic nerve.

    abstract::The ability of the rat sciatic nerve to regenerate into a previously frozen distal nerve segment was studied and compared to regeneration after a crush lesion. The regeneration rate in the frozen segment was 1.9 mm/day, which was approximately half of that observed after a crush lesion (3.3 mm/day). If an unfrozen ner...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(88)90161-8

    authors: Sjöberg J,Kanje M,Edström A

    更新日期:1988-06-21 00:00:00

  • The response of rabbit ciliary nerve to luminance intensity.

    abstract::Using cervical sympathectomized and immobilized rabbits, the relationship between the luminance intensity and the magnitude of the response in pupillo-constrictor units of the ciliary nerve was investigated. It was revealed that the intensity--response relationship of the units closely resembled that of retinal recept...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(80)90787-8

    authors: Inoue T

    更新日期:1980-11-10 00:00:00

  • Heterosynaptic stimulation modulates the duration of post-tetanic potentiation at an Aplysia synapse without affecting other aspects of synaptic transmission.

    abstract::Repetitive stimulation of an axon in the right visceropleural connective to the abdominal ganglion of Aplysia californica produces post-tetanic potentiation (PTP) of a unitary monosynaptic EPSP recorded from cell R15. PTP decays within one half hour following cessation of repatitive stimulation. Stimulation of the lef...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(80)91262-7

    authors: Newlin SA,Schlapfer WT,Barondes SH

    更新日期:1980-01-06 00:00:00

  • Release of excitatory and inhibitory amino acids from the locus coeruleus of conscious rats by cardiovascular stimuli and various forms of acute stress.

    abstract::The release of amino acids in the locus coeruleus (LC) of conscious, freely moving rats was studied in time periods of 3 min by use of push-pull superfusion under basal conditions and during application of various experimental stimuli known to influence the activity of the LC-noradrenergic system. Tail pinch for 3 min...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(95)01102-1

    authors: Singewald N,Zhou GY,Schneider C

    更新日期:1995-12-15 00:00:00

  • Regional differences in the effects of forced swimming on extracellular levels of 5-hydroxytryptamine and 5-hydroxyindoleacetic acid.

    abstract::The effects of forced swimming for 30 min on extracellular 5-hydroxytryptamine (5-HT) levels were examined in five brain regions in rats using in vivo microdialysis. A single dialysis probe was implanted under surgical anesthesia into either the striatum, ventral hippocampus, frontal cortex, amygdala, or lateral septu...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(95)00349-u

    authors: Kirby LG,Allen AR,Lucki I

    更新日期:1995-06-05 00:00:00

  • Wide therapeutic time window for nimesulide neuroprotection in a model of transient focal cerebral ischemia in the rat.

    abstract::Results from several studies indicate that cyclooxygenase-2 (COX-2) is involved in ischemic brain injury. The purpose of this study was to evaluate the neuroprotective effects of the selective COX-2 inhibitor nimesulide on cerebral infarction and neurological deficits in a standardized model of transient focal cerebra...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2004.01.078

    authors: Candelario-Jalil E,González-Falcón A,García-Cabrera M,León OS,Fiebich BL

    更新日期:2004-05-08 00:00:00

  • Opiate receptor binding in the brain of the hypertensive rat.

    abstract::Experimental and genetic hypertension in male rate is accompanied by a lower specific [3H]naloxone binding in the dorsal horn of the spinal cord, and in the hippocampus as compared to controls. Rats which are genetically resistant to hypertensive stimuli have a higher specific [3H]naloxone binding in the nucleus tract...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(81)91265-8

    authors: Zamir N,Segal M,Simantov R

    更新日期:1981-05-25 00:00:00

  • Inhibition by sodium valproate of the arginine vasopressin and adrenocorticotropin responses to angiotensin II in normal men.

    abstract::The present study was carried out in order to determine whether angiotensin II (ANG II) exerts its stimulatory effect on plasma concentration of arginine vasopressin (AVP) and adrenocorticotrophic hormone (ACTH) by interacting with a (gamma-aminobutyric acid) GABAergic pathway. For this purpose, the effect of the GABA...

    journal_title:Brain research

    pub_type: 临床试验,杂志文章

    doi:10.1016/0006-8993(89)90100-5

    authors: Coiro V,Chiodera P

    更新日期:1989-07-03 00:00:00

  • Sex differences in striatal dopamine: in vivo microdialysis and behavioral studies.

    abstract::Experiments were conducted to examine sex differences in striatal dopamine function using in vivo microdialysis in freely moving rats. We report here a sex difference in basal extracellular striatal dopamine determined by quantitative microdialysis (the no net flux method) when castrated and ovariectomized rats were c...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(93)91225-h

    authors: Castner SA,Xiao L,Becker JB

    更新日期:1993-04-30 00:00:00

  • Nitric oxide involvement in the trigeminal hyperalgesia in diabetic rats.

    abstract::Trigeminal hyperalgesia frequently appears in diabetic neuralgia altering the transmission of orofacial sensory information. This study was designed to explore the effects of trigeminal hyperalgesia in streptozotocin-induced diabetes monitoring the expression of nitric oxide synthase in the trigeminal ganglion cells. ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(00)02235-6

    authors: Rodella L,Rezzani R,Corsetti G,Bianchi R

    更新日期:2000-05-19 00:00:00

  • Cholinergic modulation of neocortical long-term potentiation in the awake, freely moving rat.

    abstract::The neocortex has proven resistant to LTP induction using standard in vitro and acute, in vivo preparations. Because the neocortex is widely thought to be involved in long-term information storage, this resistance raises questions about the validity of LTP as a memory model. Recently, we have shown that the neocortex ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(00)02720-7

    authors: Boyd TE,Trepel C,Racine RJ

    更新日期:2000-10-20 00:00:00

  • Spectral interactions in horizontal and ganglion cells of the isolated and arterially-perfused rabbit retina.

    abstract::Intracellular and extracellular recordings in the arterially-perfused eye cup of pigmented and albino rabbits show the presence of blue cones, green cones and rods. Among the ganglion cells, a fraction shows spectral opponency. Two main types were found. In one, on-depolarizing responses and on-hyperpolarizing respons...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(78)90278-0

    authors: De Monasterio FM

    更新日期:1978-07-14 00:00:00

  • S-100 protein synthesis in cultured glioma cell is G1-phase of cell cycle dependent.

    abstract::The kinetics of S-100 protein synthesis was studied in synchronized cultured glioma (C6) cells. The peak of the synthesis was detected at G1-phase of the cell cycle and apparently was not population density-dependent, since sparsely cultured G1-phase cells synthesized the same proportion of the protein per cell as tha...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(82)90462-0

    authors: Fan K

    更新日期:1982-04-15 00:00:00

  • Effects of gonadal steroids on the in vivo binding of [125I]alpha-bungarotoxin to the suprachiasmatic nucleus.

    abstract::The radioligand [125I]alpha-bungarotoxin (alpha-BTX) has been used to test receptor binding to putative nicotinic cholinergic receptors in the hypothalamus. Using light microscopic autoradiography following third ventricular infusion of the radioligand we have previously demonstrated that in normally cycling rats and ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(84)90736-4

    authors: Miller MM,Silver J,Billiar RB

    更新日期:1984-01-02 00:00:00

  • Hemispheric asymmetry in behavioral response to D1 and D2 receptor agonists in the nucleus accumbens.

    abstract::The present study examined the locomotor response of rats to unilateral injections of the mixed D1/D2 agonist apomorphine, the D2 agonist quinpirole, and the D1 agonist SKF 38393 into the left or right nucleus accumbens (NA) of male Sprague-Dawley rats. There were 2 main findings. First, unilateral (left or right) inj...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(90)91351-g

    authors: Belcheva I,Bryer JB,Starkstein SE,Honig M,Moran TH,Robinson RG

    更新日期:1990-11-19 00:00:00

  • Repeated maternal separation of male Wistar rats alters glutamate receptor expression in the hippocampus but not the prefrontal cortex.

    abstract::Stress early in life puts the individual at a greater risk for developing mental disorders in adulthood. The animal model of maternal separation involves daily removal of pups from their mother over the early postnatal period and leads to several behavioral deficits in adults. Since this period corresponds to a time o...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2006.04.136

    authors: Pickering C,Gustafsson L,Cebere A,Nylander I,Liljequist S

    更新日期:2006-07-12 00:00:00

  • Long-term potentiation in the dentate gyrus is preferentially induced at theta rhythm periodicity.

    abstract::In urethane-anesthetized rats, high frequency stimulation was applied to the medial perforant pathway at various time intervals (50, 100, 200, 350 and 500 ms) following stimulation of the same pathway by a single pulse of equal intensity. Recordings of dentate gyrus granule cell evoked responses were made to investiga...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(88)91358-3

    authors: Greenstein YJ,Pavlides C,Winson J

    更新日期:1988-01-12 00:00:00

  • Alpha 1-adrenoceptors in the adult rat barrel field: effects of deafferentation and norepinephrine removal.

    abstract::Norepinephrine (NE), acting on brain adrenoceptors, plays an important role in barrel field neuronal activity and plasticity. For this reason, the distribution of alpha 1- and alpha 2-adrenoceptors in the somatosensory cortex barrel field was studied by autoradiographic techniques in rats undergoing plastic change or ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(93)90005-8

    authors: Dunn-Meynell AA,Levin BE

    更新日期:1993-09-24 00:00:00

  • Method of administration determines the effect of naloxone on pain.

    abstract::The opiate antagonist, naloxone, produces dose-dependent biphasic changes in clinical pain. The mechanism of the analgesia produced by low dose naloxone is unknown. To study the analgesic effect of naloxone, we have used a programmable infusion pump, which eliminates placebo-induced endorphin-mediated analgesia, to ad...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(86)91653-7

    authors: Levine JD,Gordon NC

    更新日期:1986-02-19 00:00:00

  • Non-invasive in vivo spectrophotometric monitoring of brain cytochrome aa3 revisited.

    abstract::Cytochrome aa3 (cyt aa3) is the main catalyst of cellular oxygen consumption. The properties of cyt aa3 will define the tissue oxygen requirements and provide an insight into energy supply and demand. Currently dual-wavelength (605-590 or 605-620 nm) reflectance spectrophotometry is used to monitor cyt aa3 redox state...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(85)91236-3

    authors: Kariman K,Burkhart DS

    更新日期:1985-12-23 00:00:00

  • Direct relation of long-term synaptic potentiation to phosphorylation of membrane protein F1, a substrate for membrane protein kinase C.

    abstract::One hour after long-term potentiation (LTP) in the intact hippocampus, a selective increase in protein F1 in vitro phosphorylation was observed in homogenate prepared from dorsal hippocampus. Protein F1 phosphorylation was directly related to the magnitude and persistence of potentiation. No other phosphoprotein studi...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(86)91510-6

    authors: Lovinger DM,Colley PA,Akers RF,Nelson RB,Routtenberg A

    更新日期:1986-12-10 00:00:00

  • Behavioral effects of N-desmethylclozapine on locomotor activity and sensorimotor gating function in mice-Possible involvement of muscarinic receptors.

    abstract::N-desmethylclozapine (NDMC), a major circulating metabolite of the atypical antipsychotic drug, clozapine, and has M(1) muscarinic receptor partial agonistic property. The purpose of the present study was to examine whether in vivo behavioral effects of NDMC were elicited through the activation of muscarinic receptors...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2011.08.056

    authors: Maehara S,Hikichi H,Ohta H

    更新日期:2011-10-18 00:00:00