Abstract:
:At various times after spinal nerve injury, dorsal root ganglia (DRGs) from injured segments were removed with attached dorsal roots and spinal nerves. In an in vitro recording chamber, spontaneously active units were recorded from teased dorsal root fascicles. Sustained spontaneous activity could first be recorded at 13 h after the ligation, but adrenergic sensitivity did not develop until 24 h after the injury. Almost all recorded activity originated from the DRG. Thus, the DRG is the most common site for ectopic discharge generation after spinal nerve injury and separate mechanisms seem to be involved in the development of ectopic discharges and adrenergic sensitivity.
journal_name
Brain Resjournal_title
Brain researchauthors
Liu X,Chung K,Chung JMdoi
10.1016/s0006-8993(99)02165-4subject
Has Abstractpub_date
1999-12-04 00:00:00pages
244-7issue
1-2eissn
0006-8993issn
1872-6240pii
S0006-8993(99)02165-4journal_volume
849pub_type
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