Demonstration of calcitonin gene-related peptide immunoreactive axons contacting dynorphin A(1-8) immunoreactive spinal neurons in a rat model of peripheral inflammation and hyperalgesia.

abstract：:Electrophysiological studies have suggested that the excitatory actions of opioids in the hippocampal formation are mediated by inhibition of interneurons containing GABA; however, an anatomical basis for this interaction has never been established. Thus, we sought to determine the relationship between leu-enkephalin ...

journal_title：Brain research

authors： Commons KG,Milner TA

更新日期：1996-06-10 00:00:00

abstract：:The convulsant compounds bicuculline (BICUC) and penicillin (PCN) are antagonists of GABA-mediated synaptic inhibition. In addition, we have shown that BICUC and PCN produced membrane depolarization of mouse spinal cord neurons in primary dissociated cell culture by blocking a potassium conductance, a non-synaptic dir...

journal_title：Brain research

authors： Heyer EJ,Nowak LM,Macdonald RL

更新日期：1982-01-28 00:00:00

abstract：:The aim of this study was to determine if a prolonged period (7 or 14 days) of hypodynamia-hypokinesia (HH) affects the conduction of afferent input and the cortical and spinal responsiveness. Acute recordings of cortical and spinal somatosensory evoked potentials (SEPs) were performed after stimulation of the sciatic...

journal_title：Brain research

authors： Canu MH,Langlet C,Dupont E,Falempin M

更新日期：2003-07-18 00:00:00

abstract：:The L-isomer of beta-N-methylamino-L-alanine (BMAA), present in free form in seed of Cycas circinalis, elicits in spinal cord cultures a pattern of acute postsynaptic neuronal vacuolation comparable to that induced by beta-N-oxalylamino-L-alanine (BOAA), an excitotoxic amino acid of greater potency isolated from seed ...

journal_title：Brain research

authors： Nunn PB,Seelig M,Zagoren JC,Spencer PS

更新日期：1987-05-05 00:00:00

abstract：:The results of a WGA-HRP and HRP study in the cat indicated that some neurons in the marginal zone (lamina I) of the caudal spinal trigeminal nucleus sent their axons contralaterally to the striatum; mainly to the dorsal part of the putamen, and additionally to the ventrolateral part of the caudate nucleus, at the ste...

journal_title：Brain research

authors： Yasui Y,Itoh K,Mizuno N

更新日期：1987-04-07 00:00:00

abstract：:Analysis of rat hypothalamic extracts by gel filtration and HPLC revealed the presence of a form of substance P-like immunoreactivity with a molecular weight of approximately 5,700 (6k-SP). 6k-SP is probably an N-terminally extended form of substance P; the peptide may be an intermediate in SP biosynthesis, or may fun...

journal_title：Brain research

authors： Harmar AJ,Armstrong A,Lee CM,Emson PC

更新日期：1984-12-10 00:00:00

abstract：:Ion channels are integral membrane proteins that allow passive diffusion of ions across membranes. In neurons and in other excitable cells, the harmonious coordination between the numerous types of ion channels shape and propagate electrical signals. Increased accumulation of reactive oxidative species (ROS), and subs...

journal_title：Brain research

authors： Patel R,Sesti F

更新日期：2016-05-15 00:00:00

abstract：:The purpose of this work was to characterize the gap junctions between cultured glomus cells of the rat carotid body and to assess the effects of acidity and accompanying changes in [Ca(2+)](i) on electric coupling. Dual voltage clamping of coupled glomus cells showed a mean macrojunctional conductance (G(j)) of 1.16 ...

journal_title：Brain research

authors： Abudara V,Jiang RG,Eyzaguirre C

更新日期：2001-10-19 00:00:00

abstract：:The projections of putative dopamine containing cells within the dorsal raphe nucleus (DR) were studied using a combination of tyrosine hydroxylase (TH) immunocytochemistry and fluorescent retrograde tracing. Substantial numbers of TH-immunoreactive cells in the DR were found to project to the nucleus accumbens. Progr...

journal_title：Brain research

authors： Stratford TR,Wirtshafter D

更新日期：1990-03-12 00:00:00

abstract：:Systemic administration of the protein synthesis inhibitor, cycloheximide, induced both phase advances and phase delays in the circadian rhythm of wheel-running activity in hamsters (Mesocricetus auratus) maintained in constant darkness or constant light. The magnitude and direction of the phase shifts were dependent ...

journal_title：Brain research

authors： Wollnik F,Turek FW,Majewski P,Takahashi JS

更新日期：1989-09-04 00:00:00

abstract：:Extracellular recordings of action potentials were made from neurones antidromically identified as neurosecretory cells in the paraventricular and supraoptic nuclei of urethane-anesthetized female rats. Eighty-six neurones were examined for their responsiveness to 10 ng of angiotensin II (AII) injected into the third ...

journal_title：Brain research

authors： Akaishi T,Negoro H,Kobayasi S

更新日期：1980-04-28 00:00:00

abstract：:We compared the effect of mecamylamine and fluoxetine on the hippocampal noradrenaline (NA) release evoked by nicotine in vitro. Nicotine (100 microM) increased the basal release of [3H]NA from rat hippocampal slices. This effect was blocked by the potent nicotinic antagonist mecamylamine in a dose-dependent manner (I...

journal_title：Brain research

authors： Hennings EC,Kiss JP,Vizi ES

更新日期：1997-06-13 00:00:00

abstract：:Application of the cholinergic agonist, carbachol, produced theta-like rhythmical waveforms, recorded in the stratum moleculare of the dentate gyrus in the cat hippocampal formation slices. This effect of carbachol was antagonized by atropine but not D-tubocurarine. These results provide first direct evidence that the...

journal_title：Brain research

authors： Konopacki J,Gołebiewski H,Eckersdorf B

更新日期：1992-04-24 00:00:00

abstract：:It has been shown that 2-deoxy-D-glucose (2-DG) inhibits glucose utilization and elicits feeding through the lateral hypothalamus. In contrast, 2,5-anhydro-D-mannitol (2,5-AM), blocking glycogenolysis and/or gluconeogenesis, elicits feeding through the ventromedial hypothalamus. The aim of the present study was to det...

journal_title：Brain research

authors： Morita H,Fujimoto K,Sakata T,Kurokawa M,Yoshimatsu H,Noda T,Iwakiri R,Sakai T

更新日期：1996-05-06 00:00:00

abstract：:Intracerebroventricular microinjection of thyrotropin-releasing hormone (TRH) potently blocked the development of, as well as promptly reversed, epinephrine-stimulated hyperglycemia in mice. The central antihyperglycemic effect was dose-related (0.1-10 micrograms), could be reproduced by an intravenous injection of a ...

journal_title：Brain research

authors： Amir S,Harel M,Rivkind AI

更新日期：1987-12-01 00:00:00

abstract：:Little is known about the movement of 5-aminolevulinic acid (delta-aminolevulinic acid; ALA) between blood and brain. This is despite the fact that increases in brain ALA may be involved in generating the neuropsychiatric symptoms in porphyrias and that systemic administration of ALA is currently being used to delinea...

journal_title：Brain research

authors： Ennis SR,Novotny A,Xiang J,Shakui P,Masada T,Stummer W,Smith DE,Keep RF

更新日期：2003-01-10 00:00:00

abstract：:The cholinergic innervation of the mediodorsal (MD) nucleus of the thalamus was visualized immunohistochemically in human brain postmortem, using an antibody against human choline acetyltransferase (ChAT). The ChAT staining of the MD nucleus was more intense than in the surrounding thalamic nuclei but weaker than that...

journal_title：Brain research

authors： Brandel JP,Hirsch EC,Hersh LB,Javoy-Agid F

更新日期：1990-05-07 00:00:00

abstract：:We have identified an inhibitory neuron (RPL4) in the right pleural ganglion of Aplysia, which produced hyperpolarization of the sensory and motor neurons involved in the tail withdrawal reflex. Activation of RPL4 significantly reduced the amplitude of excitatory postsynaptic potentials produced in tail motor neurons ...

journal_title：Brain research

authors： Buonomano DV,Cleary LJ,Byrne JH

更新日期：1992-04-10 00:00:00

abstract：:Immunocytochemical and immunoblotting technique have been used to characterize the antigens recognized by two monoclonal antibodies (MAbs C6 and D5) produced against dissociated cells from punches of neonatal supraoptic (SON) and paraventricular (PVN) hypothalamic nuclei of the rat. Peroxidase immunocytochemistry reve...

journal_title：Brain research

authors： Paden CM,Hapner SJ

更新日期：1991-04-05 00:00:00

abstract：:We sought to further elucidate signal transduction pathways for the I(1)-imidazoline receptor in PC12 cells and their interaction with the well-characterized signaling events triggered by nerve growth factor (NGF) in these cells. Stimulation of the I(1)-imidazoline receptor with moxonidine, a centrally acting antihype...

journal_title：Brain research

authors： Edwards L,Ernsberger P

更新日期：2003-08-01 00:00:00

abstract：:Intracellular Ca2+, measured in NCB-20 cells with the fluorescent indicator fura-2, was elevated by K(+)-depolarization and by ethanol, but not by the excitatory amino acids L-glutamate and N-methyl-D-aspartate. These amino acids failed to raise intracellular Ca2+ levels even in the presence of elevated extracellular ...

journal_title：Brain research

authors： Chan J,Greenberg DA

更新日期：1991-01-25 00:00:00

abstract：BACKGROUND:Previous studies have shown that regulating the target region by real-time fMRI-based neurofeedback training can influence the activation of other regions and the functional connectivity between them. However, it is not clear whether the training effect of neurofeedback, especially in emotion regulation, is ...

journal_title：Brain research

authors： Liu N,Yao L,Zhao X

更新日期：2020-08-01 00:00:00

abstract：:The immunosuppressive macrolide FK-506 has been shown to protect neurons in culture against glutamate excitotoxicity. This effect was attributed to the binding of immunosuppressants to calcineurin-inhibiting immunophilins. We now report that also the non-immunosuppressive macrolide antibiotics protect neurons in cultu...

journal_title：Brain research

authors： Manev H,Favaron M,Candeo P,Fadda E,Lipartiti M,Milani D

更新日期：1993-10-08 00:00:00

abstract：:We compared changes in levels of substance P-like immunoreactivity (SPLI) in L4-6 dorsal root ganglia (DRG), L4-6 dorsal roots, sciatic nerve, tibial nerve and hind foot skin in rats following resection or crush injury of the sciatic nerve. The initial depletion of SPLI, which occurred in all areas sampled, was simila...

journal_title：Brain research

authors： Bisby MA,Keen P

更新日期：1986-02-12 00:00:00

abstract：:In seven female alpha-chloralose-anesthetized cats, 52 lateral thalamic neurons were tested with noxious distension of the urinary bladder, the distal colon and the lower esophagus. In addition, the neurons were characterized with innocuous and noxious mechanical stimulation of the skin and deep structures. Of the 52 ...

journal_title：Brain research

authors： Horn AC,Vahle-Hinz C,Brüggemann J,Petersen M,Kniffki KD

更新日期：1999-12-18 00:00:00

abstract：:Amitriptyline, a representative tricyclic antidepressant, has been widely used for the treatment of neuropathic pain, such as post-herpetic and trigeminal neuralgia. In the present study, we investigated the effect of amitriptyline on glycinergic spontaneous miniature inhibitory postsynaptic currents (mIPSCs) in acute...

journal_title：Brain research

authors： Cho JH,Choi IS,Lee MG,Jang IS

更新日期：2012-05-21 00:00:00

abstract：:Region-specific noradrenergic inputs to the bed nuclei of the stria terminalis (BST) from the caudal medulla were studied using combined Fast Blue injections and tyrosine hydroxylase immunoreactivity (TH-ir). Injections into the rostral, dorsal, ventral and lateral BST resulted in predominantly ipsilateral retrograde ...

journal_title：Brain research

authors： Terenzi MG,Ingram CD

更新日期：1995-02-20 00:00:00

abstract：:In terrestrial gastropod mollusks (slugs and snails), olfaction is the dominant sensory modality guiding various kinds of behavior. Anatomical studies indicate that olfactory information is processed in the brain (the cerebral ganglion) in two lobes in particular: the procerebrum (PC) and the metacerebrum (MtC). This ...

journal_title：Brain research

authors： Makinae H,Makino Y,Obara T,Yano M

更新日期：2008-09-22 00:00:00

abstract：:The present study aimed to evaluate the therapeutic potential of apocynin, an NADPH oxidase assembly inhibitor, on traumatic brain injury. Rat traumatic brain injury (TBI) was performed using a weight drop model. Apocynin (100mg/kg) was injected into the intraperitoneal space 15 min before TBI. Reactive oxygen species...

journal_title：Brain research

authors： Choi BY,Jang BG,Kim JH,Lee BE,Sohn M,Song HK,Suh SW

更新日期：2012-10-24 00:00:00

abstract：:Treatment of castrated quail with testosterone (T) reliably activates male copulatory behavior and, at the same time, increases the aromatase activity (AA), the number of aromatase-immunoreactive (ARO-ir) cells and the concentration of aromatase mRNA as measured by RT-PCR in the brain. All these effects can be mimicke...

journal_title：Brain research

authors： Foidart A,Tlemçani O,Harada N,Abe-Dohmae S,Balthazart J

更新日期：1995-12-01 00:00:00