Abstract:
:We have identified an inhibitory neuron (RPL4) in the right pleural ganglion of Aplysia, which produced hyperpolarization of the sensory and motor neurons involved in the tail withdrawal reflex. Activation of RPL4 significantly reduced the amplitude of excitatory postsynaptic potentials produced in tail motor neurons by action potentials triggered in sensory neurons. This example of heterosynaptic inhibition was due, at least in part, to an increase in membrane input conductance in the motor neuron. Since the synaptic strength of the sensory-to-motor neuron connection has been associated with the strength of the tail withdrawal reflex, RPL4 may contribute to modulation of that reflex.
journal_name
Brain Resjournal_title
Brain researchauthors
Buonomano DV,Cleary LJ,Byrne JHdoi
10.1016/0006-8993(92)90548-nsubject
Has Abstractpub_date
1992-04-10 00:00:00pages
147-50issue
1eissn
0006-8993issn
1872-6240pii
0006-8993(92)90548-Njournal_volume
577pub_type
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