Abstract：
:Pineal glands of male Syrian hamsters stimulated in vivo with isoproterenol (ISO) for 4 h before the onset of darkness showed a 4-h advance in the timing of the nighttime increases in both N-acetyltransferase activity and melatonin levels. When ISO (1 mg/kg) was administered every 2 h to animals kept in light during the night, a significant increase in melatonin synthesis was observed after 4-6 h. The results suggest that the Syrian hamster pineal gland can respond in vivo to continuous beta-adrenergic stimulation, but a lag period of 4-6 h is required before there is an increase in melatonin synthesis.
journal_name
Brain Resjournal_title
Brain researchauthors
Gonzalez-Brito A,Reiter RJ,Santana C,Menendez-Pelaez A,Guerrero JMdoi
10.1016/0006-8993(88)90633-6subject
Has Abstractpub_date
1988-12-20 00:00:00pages
393-6issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(88)90633-6journal_volume
475pub_type
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