Distribution of [3H]AMPA binding sites in rat brain as determined by quantitative autoradiography.

abstract：:The effects of diazepam, nitrazepam, clonazepam, and Ro5-4864 on transient (type I) and long-lasting (type II) calcium channels associated with low-affinity benzodiazepine receptors were investigated using the whole-cell patch-clamp technique. Clonazepam (100 microM), a specific agonist for the central-type benzodiaze...

journal_title：Brain research

authors： Watabe S,Yoshii M,Ogata N,Tsunoo A,Narahashi T

更新日期：1993-03-26 00:00:00

abstract：:The opposing actions of diphenylhydantoin (DPH) and calcium on the level of [32P]phosphate incorporation into particular rat and human brain proteins have been demonstrated in this study by employing the techniques of acrylamide gel electrophoresis and autoradiography. In the presence of calcium several brain proteins...

journal_title：Brain research

authors： DeLorenzo RJ

更新日期：1977-09-23 00:00:00

abstract：:The location and morphological characteristics of gamma-aminobutyric acid (GABA)-immunopositive cells and their processes were studied in rat and mouse first somatosensory (SI) cortex (including 'barrels') in layer IV, and layers above (I-III), and below (V and VI). In coronal sections of SI cortex of both species GAB...

journal_title：Brain research

authors： Chmielowska J,Stewart MG,Bourne RC

更新日期：1988-01-26 00:00:00

abstract：:MicroRNAs (miRNAs) are abundantly expressed in the brain and play an important role in disorders of the brain, including Alzheimer's diseases (AD). Growing body of evidence suggests that the TGF-β signaling pathway plays a key role in the pathogenesis of AD. However, it is unclear whether miRNAs involved in AD pathoge...

journal_title：Brain research

authors： Wang H,Liu J,Zong Y,Xu Y,Deng W,Zhu H,Liu Y,Ma C,Huang L,Zhang L,Qin C

更新日期：2010-10-21 00:00:00

abstract：:High (2.5-5 micrograms) doses of ventral tegmental morphine, which normally facilitate brain stimulation reward, were found to cause a complete cessation of bar pressing for brainstem stimulation in animals pretreated with systemic pimozide (0.175-0.35 mg/kg). It was hypothesized that the behavioral failure was due to...

journal_title：Brain research

authors： Rompré PP,Wise RA

更新日期：1989-01-16 00:00:00

abstract：:The location of stapedius motoneurons in the rat was determined with horseradish peroxidase (HRP) retrograde tracing techniques. After injection of free HRP or wheat germ agglutinin-horseradish peroxidase (WGA-HRP) in the stapedius muscle on one side, labeled neurons were seen ipsilaterally in a region ventromedial to...

journal_title：Brain research

authors： Rouiller EM,Capt M,Dolivo M,De Ribaupierre F

更新日期：1989-01-02 00:00:00

abstract：:The localization of immunoreactive glutamic acid decarboxylase (GAD) and enkephalin-like immunoreactivity was examined in serial, 4-micron frozen sections of the caudate nucleus from rats pretreated with colchicine. Colocalization was found in numerous caudate neurons of medium size. Cell counts of corresponding label...

journal_title：Brain research

authors： Aronin N,Difiglia M,Graveland GA,Schwartz WJ,Wu JY

更新日期：1984-05-23 00:00:00

abstract：:Carbonic anhydrase (CA) and cholinesterase (CE) histochemical staining of rabbit spinal nerve roots and dorsal root ganglia demonstrated that among the reactive myelinated axons, with minor exceptions, sensory axons were CA positive and CE negative whereas motor axons were CA negative and CE positive. The high specifi...

journal_title：Brain research

authors： Riley DA,Sanger JR,Matloub HS,Yousif NJ,Bain JL,Moore GH

更新日期：1988-06-21 00:00:00

abstract：:The distribution of avian pancreatic polypeptide (APP)-like immunoreactivity (APP-IR) in the chicken retina was investigated by means of immunohistochemistry. The observation from frozen sections showed that APP-IR is localized in the stratified amacrine cells of the first sublayer. Examination of whole-mounts reveale...

journal_title：Brain research

authors： Katayama Y,Kiyama H,Arai Y,Tohyama M

更新日期：1984-09-17 00:00:00

abstract：:Focal cerebral ischemia elicits an inflammatory response characterized by the infiltration and accumulation of leukocytes, as well as the secretion of inflammatory mediators (Clark et al., Brain Res. Bull., 35 (1994) 387-392; Garcia et al., Am. J. Pathol., 144 (1994) 188-199; Wang et al., J. Neurochem. 71 (1998) 1194-...

journal_title：Brain research

authors： Che X,Ye W,Panga L,Wu DC,Yang GY

更新日期：2001-06-01 00:00:00

abstract：:Tetanization of commissural-CA1 input to the apical dendrites of the dorsal hippocampal CA1 area was found to produce a marked long-term potentiation of the field EPSP. Whereas by concurrent tetanization of the commissural pathway and medial septo-CA1 input, this potentiation was significantly reduced. Thus a negative...

journal_title：Brain research

authors： Xie XP

更新日期：1988-04-05 00:00:00

abstract：:Three types of hyperpolarization in response to applied acetylcholine (ACh) were observed in 4 identified neurones (RP1, RP2, RP3 and RP4) in the right parietal ganglion of the African giant snail, Achatina fulica Férussac. In order to clarify the ionic mechanisms of these responses, the neurones were voltage-clamped ...

journal_title：Brain research

authors： Furukawa Y,Kobayashi M

更新日期：1986-05-28 00:00:00

abstract：:Dissociated striatal neurons exhibited increased neurite outgrowth when co-cultured with myenteric plexus explants. Enriched enteric neurons or enriched enteric glia produced a less marked response; non-ganglionic cells had no effect. Increases in striatal neuron and glial cell numbers were seen in all co-cultures. Te...

journal_title：Brain research

authors： Höpker VH,Saffrey MJ,Burnstock G

更新日期：1994-06-20 00:00:00

abstract：:A possible functional relationship between corticotropin-releasing factor (CRF) and opiate peptide neuronal systems (beta-endorphin, dynorphin1-17 and Met-enkephalin) and their interactions with gonadotropin releasing hormone (GnRH) in the mesencephalic central gray (MCG) for the regulation of lordosis behaviour was a...

journal_title：Brain research

authors： Sirinathsinghji DJ

更新日期：1985-06-10 00:00:00

abstract：:The vomeronasal organ of rat was cultured from embryonic 15-day littermates. During 4-8 days in vitro, vomeronasal axons originating from the explants of vomeronasal organ formed 2-3 large fascicles. When Vicia villosa agglutinin (VVA) was added to the culture medium, fasciculation of the vomeronasal axons was inhibit...

journal_title：Brain research

authors： Ichikawa M,Osada T,Graziadei PP

更新日期：1994-12-30 00:00:00

abstract：:This study used microdialysis to monitor extracellular levels of 5-HT and its metabolite, 5-hydroxyindole acetic acid (5-HIAA) in the lateral hypothalamus (LH) and hippocampus of freely moving rats that had developed a CTA to a 2.5 mM saccharin solution (CS) following its pairing with illness induced by lithium chlori...

journal_title：Brain research

authors： West HL,Mark GP,Hoebel BG

更新日期：1991-08-09 00:00:00

abstract：:The hypothesis according to which BoTx and TeTx block neuromuscular transmission by impairing Ca2+ influx was tested by recording presynaptic membrane currents at motor endplates of the mouse by means of external electrodes. The use of K-channel blockers allowed us to observe inward Ca current which was unaffected by ...

journal_title：Brain research

authors： Dreyer F,Mallart A,Brigant JL

更新日期：1983-07-04 00:00:00

abstract：:Benzodiazepine (BZ) site ligands affect vigilance, anxiety, memory processes, muscle tone and epileptogenic propensity through modulation of neurotransmission at GABA(A) receptors containing alpha1, alpha2, alpha3 or alpha5 subunits, and may have numerous experimental and clinical applications. The ability of non-sele...

journal_title：Brain research

authors： Savić MM,Clayton T,Furtmüller R,Gavrilović I,Samardzić J,Savić S,Huck S,Sieghart W,Cook JM

更新日期：2008-05-07 00:00:00

abstract：:Practical utilization of in vivo electrochemistry for brain studies has been impeded by difficulties with specificity and quantitative measurements. Studies in brain slices combined with similar data from intact animals have provided important new information on the nature of the electrochemical studies. Using the enz...

journal_title：Brain research

authors： Schenk JO,Miller E,Rice ME,Adams RN

更新日期：1983-10-24 00:00:00

abstract：:Close to 20% of the patients infected with the AIDS virus develops neurological deficit; eventhough HIV does not invade neurons. Consistently with the neurological deficit, HIV(+) subjects show abnormalities in brainstem auditory and visual evoked potentials (BSAEP and VEP) and in sleep patterns. The HIV-derived glyco...

journal_title：Brain research

authors： Prospéro-García O,Huitrón-Resendiz S,Casalman SC,Sánchez-Alavez M,Díaz-Ruiz O,Navarro L,Lerner DL,Phillips TR,Elder JH,Henriksen SJ

更新日期：1999-07-31 00:00:00

abstract：:Intraperitoneal (i.p.) administration of sulfated CCK octapeptide (CCK-8S) has been shown to induce changes in neuronal activity in the nucleus of the solitary tract (NTS) and area postrema (AP), sensory parts of the dorsal vagal complex (DVC), and in the paraventricular nucleus of the hypothalamus (PVN), as determine...

journal_title：Brain research

authors： Mönnikes H,Lauer G,Arnold R

更新日期：1997-10-03 00:00:00

abstract：:We investigated the localization of components of translational machinery and their regulators in the postsynaptic region. We examined several components, especially those involved in translational regulation: components of (1) MAPK-Mnk-eIF4E, (2) PI3-kinase-PDK-Akt/PKB-FRAP/mTOR-PHAS/4EBP, (3) p70S6K-S6 ribosomal pro...

journal_title：Brain research

authors： Asaki C,Usuda N,Nakazawa A,Kametani K,Suzuki T

更新日期：2003-05-16 00:00:00

abstract：:The purpose of this study was to determine the effects of aging and gender on the volumes of total brain, brainstem, cerebellum and lateral ventricle of healthy Koreans by magnetic resonance imaging (MRI). Using three-dimensional MRI volumetry, we compared the volumes of various brain regions according to age and gend...

journal_title：Brain research

authors： Lee NJ,Park IS,Koh I,Jung TW,Rhyu IJ

更新日期：2009-06-18 00:00:00

abstract：:Responses of antennal olfactory receptors of the Colorado potato beetle (Leptinotarsa decemlineata Say) to stimulation with 5 general green odour components, i.e. cis-3-hexen-1-ol, trans-2-hexenal, cis-3-hexenyl acetate, trans-2-hexen-1-ol and 1-hexanol, were recorded extracellularly. Response spectra derived from the...

journal_title：Brain research

authors： De Jong R,Visser JH

更新日期：1988-04-26 00:00:00

abstract：:The present study was designed to determine the types of acetylcholine receptors involved in the initiation of epileptic seizures from the zona incerta and surrounding structures by cholinergic stimulation in rats. Unilateral intracerebral microinjection of the mixed muscarinic and nicotinic agonist carbachol (3 micro...

journal_title：Brain research

authors： Cruickshank JW,Brudzynski SM,McLachlan RS

更新日期：1994-04-18 00:00:00

abstract：:In addition to synaptic remodeling, formation of new neurons is increasingly acknowledged as an important cue for plastic changes in the central nervous system. Whereas all vertebrates retain a moderate neuroproliferative capacity, phylogenetically younger mammals become dramatically impaired in this potential during ...

journal_title：Brain research

authors： Alpár A,Künzle H,Gärtner U,Popkova Y,Bauer U,Grosche J,Reichenbach A,Härtig W

更新日期：2010-05-12 00:00:00

abstract：OBJECTIVE:This study aimed to investigate whether β-amyloid (Aβ) was able to enhance neurocan expression in a Sox9 dependent manner in astrocytes. METHODS AND MATERIALS:Astrocytes were incubated with Aβ at different concentrations, the expression of Sox9 and neurocan was detected by Western blot assay. Meanwhile, the ...

journal_title：Brain research

authors： Yan H,Zhu X,Xie J,Zhao Y,Liu X

更新日期：2016-09-01 00:00:00

abstract：:Rapid skin indentations can produce strong tap-like sensations that contain little information about skin indentation depth. Although slower stimuli produce weaker sensations, subjects can more accurately identify how the position of the skin surface changes with respect to the deeper tissues. This dissociation betwee...

journal_title：Brain research

authors： Horch KW,Tuckett RP,Burgess PR

更新日期：1984-09-10 00:00:00

abstract：:The development of hypertension in spontaneously hypertensive rats (SHR) and hyperactive voiding in rats with urethral obstruction are characterized by abnormal smooth muscle growth, increased tissue levels of nerve growth factor (NGF) and altered patterns of innervation. The present study was undertaken to determine ...

journal_title：Brain research

authors： Spitsbergen JM,Clemow DB,McCarty R,Steers WD,Tuttle JB

更新日期：1998-04-20 00:00:00

abstract：:Lesions of the anterior hypothalamus-medial preoptic area (AH-MPOA) impair courtship and copulatory behavior in male Cnemidophorus inornatus, a sexually reproducing species of whiptail lizard, and male-like pseudosexual behaviors in C. uniparens, an all-female species. These results suggest that, since C. inornatus is...

journal_title：Brain research

authors： Kingston PA,Crews D

更新日期：1994-04-18 00:00:00