Abstract：
:Dissociated striatal neurons exhibited increased neurite outgrowth when co-cultured with myenteric plexus explants. Enriched enteric neurons or enriched enteric glia produced a less marked response; non-ganglionic cells had no effect. Increases in striatal neuron and glial cell numbers were seen in all co-cultures. Tetrodotoxin abolished the neuritogenic response of myenteric plexus explants but did not affect increases in cell numbers. These observations suggest that spontaneous neuronal activity within the myenteric plexus is involved in the release of a neuritogenic factor(s), possibly from glial cells, and that this is distinct from the factor(s) affecting striatal cell numbers.
journal_name
Brain Resjournal_title
Brain researchauthors
Höpker VH,Saffrey MJ,Burnstock Gdoi
10.1016/0006-8993(94)91137-1subject
Has Abstractpub_date
1994-06-20 00:00:00pages
332-6issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(94)91137-1journal_volume
648pub_type
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