Abstract:
:Interactive-activation models posit that visual word recognition involves co-activation of orthographic neighbors (e.g., note, node) and competition among them via lateral inhibitory connections. Behavioral evidence of this lexical competition comes from masked priming paradigms, in which target words elicit slower responses when preceded by a neighbor (e.g., note-NODE) than when preceded by an unrelated word (e.g., kiss-NODE). In the present study, we used ERPs to investigate how masked high frequency word primes influence processing of low frequency word and pseudoword targets. Word targets preceded by a neighbor prime elicited larger negativities within the N400 window than those preceded by an unrelated prime across bilateral anterior sites, which we call a reversed N400 priming effect. Consistent with the behavioral literature, the size of the reversed N400 priming effect was larger for targets from high-density orthographic neighborhoods and for participants who scored higher on a behavioral measure of spelling recognition. Indeed, the opposite effect (i.e., smaller negativities within the N400 window for word targets preceded by a neighbor) was observed for words from low-density orthographic neighborhoods and for less-skilled spellers. Traditional priming was also observed within the N250 window for word targets and within both the N250 or N400 windows for pseudoword targets. The specificity of the reversed N400 priming effect to situations in which both words have precise lexical representations suggests that it, like the behavioral interference effect, indexes lexical competition during visual word recognition.
journal_name
Brain Resjournal_title
Brain researchauthors
Meade G,Grainger J,Midgley KJ,Emmorey K,Holcomb PJdoi
10.1016/j.brainres.2018.01.029subject
Has Abstractpub_date
2018-04-15 00:00:00pages
29-41eissn
0006-8993issn
1872-6240pii
S0006-8993(18)30044-1journal_volume
1685pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract::The aim of the present study was to elucidate the effects of granulocyte colony-stimulating factor (G-CSF)-mediated mobilization of bone marrow-derived stem cells on the injured spinal cord. Bone marrow cells of green fluorescent protein (GFP) transgenic mice were transplanted into lethally irradiated C57BL/6 mice. Fo...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2007.02.058
更新日期:2007-05-29 00:00:00
abstract::Horeradish peroxidase was injected at multiple sites in the mandibular and sublingual salivary glands in order to label the preganglionic salivatory neurons in the brain stem. The same injections resulted in retrograde labeling of the sympathetic and sensory neurons that project to these glands. Labeled fusiform and m...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90092-x
更新日期:1980-05-12 00:00:00
abstract::We used two approaches to test the possibility that changes in presynaptic calcium currents might be responsible for the long-term potentiation (LTP) effect induced by high-frequency stimulation in area CA1 of hippocampal slices. In a first series of experiments, we compared the effect of LTP induction on paired-pulse...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(89)91631-4
更新日期:1989-02-13 00:00:00
abstract::We have previously reported progressive reactive astrocytes in the cerebellum of taiep rats, one of the most regions affected by demyelination, and activation of cerebellar glial cells in vitro. Based on the hypothesis that activated glial cells produce high levels of reactive nitrogen intermediates, we assessed the p...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2006.08.097
更新日期:2006-11-22 00:00:00
abstract::During a simple reaction time task using auditory or visual stimuli, a total of 96 single units were recorded from the dorsolateral prefrontal cortex of macaque monkeys. These monkeys were trained to depress a lever for a fixed period which produced a tone burst or a small spot of light. After a variable period, the s...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(82)91025-3
更新日期:1982-09-09 00:00:00
abstract::Swimmeret mechanostimulation initiates an abdominal extension program which includes flexion inhibition. Agonists and antagonists were used to examine the GABAergic nature of inhibitory responses recorded intracellularly from a flexion producing interneuron (FPI 303) and flexor motor neuron (f3) pair, and extracellula...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(91)90440-7
更新日期:1991-01-11 00:00:00
abstract::The trisomy-16 mouse is considered to be a model of human trisomy-21 (Down syndrome). We have examined the electrical membrane properties of cultured dorsal root ganglion (DRG) neurons from normal and trisomy-16 fetuses. Trisomy-16 neurons had significantly accelerated rates of action potential depolarization and repo...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(89)90678-1
更新日期:1989-04-17 00:00:00
abstract::Natural stimulation was used to map the receptive fields of single cells recorded from the rostral medial portion of the dorsal accessory olive (rDAO) and the subjacent principal olive (PO) of the barbiturate anesthetized cat. Previous reports indicated a somatotopic mapping of the entire contralateral body within the...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(93)91742-b
更新日期:1993-03-12 00:00:00
abstract::In rats kainic acid-induced seizures were accompanied by time-dependent cerebral cysteinyl-leukotriene (LT) and prostaglandin (PG) F2 alpha formation. Cysteinyl-LT were identified in the rat brain tissue extracts by their immunoreactive properties and their retention times upon reversed phase HPLC profiling. In perfus...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(90)90579-z
更新日期:1990-05-07 00:00:00
abstract::Melanotropinergic neurons in the brain may mediate the known modulatory effects of alpha-melanocyte stimulating hormone (alpha-MSH) and adrenocorticotropic hormone (ACTH) on brain functions including thermoregulation, pituitary regulation, learning and behavior. To determine the distribution of brain melanotropin rece...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(90)90016-5
更新日期:1990-12-17 00:00:00
abstract::Repeated cocaine exposure alters medial prefrontal cortex (mPFC) function to allow for enhanced excitatory transmission to the nucleus accumbens and ventral tegmental area (VTA). Previous studies have demonstrated changes in receptor function in the mPFC in animals repeatedly exposed to cocaine that produced increased...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2018.07.029
更新日期:2018-11-01 00:00:00
abstract::High-affinity uptake of norepinephrine (NE) and dopamine (DA) were determined in synaptosomes of brain regions from four genetically related inbred rat strains, all derived from the Wistar-Kyoto rat: SHR, WKY, WKHA and WKHT strains. SHRs express hypertension and hyperactivity, WKHAs express hyperactivity alone, WKHTs ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(92)91369-p
更新日期:1992-07-17 00:00:00
abstract::The location of stapedius motoneurons in the rat was determined with horseradish peroxidase (HRP) retrograde tracing techniques. After injection of free HRP or wheat germ agglutinin-horseradish peroxidase (WGA-HRP) in the stapedius muscle on one side, labeled neurons were seen ipsilaterally in a region ventromedial to...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(89)91532-1
更新日期:1989-01-02 00:00:00
abstract::The effects of chronic administration of naloxone, morphine and met-enkephalin on benzodiazepine (BDZ) receptor binding in rat brain were determined 2 and 50 days after treatments were accomplished. Two days after naloxone treatment (75 micrograms/h s.c. for 14 days), enhanced BDZ receptor binding was observed in cing...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(93)91668-i
更新日期:1993-05-28 00:00:00
abstract::Selective lesions of the noradrenergic systems of the paraventricular nucleus (PVN) of the hypothalamus with 6-hydroxydopamine (6-OHDA) lengthen the periodicity of the migrating myoelectric complex (MMC), an index of intestinal motility, in rats. These lengthening effects resemble those obtained after lesions of the l...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(10)80045-9
更新日期:1992-06-26 00:00:00
abstract::Responsiveness of single inferotemporal (IT) neurons to a tone as a start or warning signal in each test trial was investigated in monkeys performing visual discrimination of 4 patterns. It was found that the same IT neurons were responsive to both auditory signal and visual discriminanda with different response chara...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(87)80031-8
更新日期:1987-04-28 00:00:00
abstract::Male Wistar rats were anaesthetized, injected intracisternally (i.c.) with saline or colchicine and were decapitated at various time intervals. Trunk blood was collected for the determination of immunoreactive adrenocorticotropic hormone (ACTHi) by radioimmunoassay (RIA) and of corticosterone by a fluorometric assay. ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(88)91517-x
更新日期:1988-03-01 00:00:00
abstract::The synaptic relationship between neuronal structures reacting with antibodies to tyrosine hydroxylase (TH) and Leu- or Met-enkephalin (ENK) was studied by the 'mirror technique' in adjacent sections of rat neostriatum. TH-immunoreactive (TH-IR) axonal boutons surrounding the neural perikarya and proximal dendrites of...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(86)91622-7
更新日期:1986-03-05 00:00:00
abstract::Regeneration of severed hypothalamic peptidergic neurosecretory axons into the ventral pia-arachnoid was observed in rats at the light microscopic and fine-structural levels. A temporal increase occurred in the number of neurophysin-positive axons regenerating into the leptomeninges for distances up to 3.3 mm by 40 da...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(88)91557-0
更新日期:1988-05-31 00:00:00
abstract::A substantial part of language understanding depends on our previous experiences, but part of it consists of the creation of new meanings. Such new meanings cannot be retrieved from memory but still have to be constructed. The goals of this article were: first, to explore the nature of new meaning creation, and second...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2007.09.014
更新日期:2007-12-05 00:00:00
abstract::Following codepletion of endogenous serotonin (5-HT, greater than 90%) and thyrotropin-releasing hormone (TRH, 66%) by neonatal treatment with the serotonergic neurotoxin, 5,7-dihydroxytryptamine (DHT), a 33% (n = 12, P less than 0.01) increase in specific TRH receptor binding was observed in adult rat spinal cord (SC...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(89)90209-6
更新日期:1989-02-20 00:00:00
abstract::Metabotropic glutamate receptors (mGluRs) are thought to mediate diverse processes in brain including synaptic plasticity and excitotoxicity. These receptors are often divided into three groups by their pharmacological profiles. [3H]Glutamate binding in the presence of compounds selective for ionotropic glutamate rece...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(97)00818-4
更新日期:1997-10-31 00:00:00
abstract::The choroid plexus epithelium constitutes the structural basis of the blood-cerebrospinal fluid barrier. We previously demonstrated that Streptococcus suis (S. suis), a relevant cause of bacterial meningitis in pigs and humans, affects porcine choroid plexus epithelial cell (PCPEC) barrier function and integrity. We n...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2006.05.041
更新日期:2006-07-19 00:00:00
abstract::Recent studies have confirmed the presence of insulin receptors in the rat brain although their function has still not been well defined. The present study explores the possibility that insulin receptors in the brain can alter or contribute to central neurotransmission. Insulin caused a dose-dependent inhibition of hi...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(84)91028-x
更新日期:1984-08-20 00:00:00
abstract::Presumptive neurons, immature neurons and degenerating structures were found in the intermediate and deep layers of the superior colliculus of normal cats over the age range 7-45 days postnatal. Electron microscopical analysis revealed these structures to be unexpectedly frequent in the early postnatal period. There w...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0165-3806(84)90013-0
更新日期:1984-05-01 00:00:00
abstract::Activation of immune cells by pathogens induces the release of a variety of proinflammatory cytokines, including IL-1 beta and TNF-alpha. Previous studies using IL-1 beta have demonstrated that this cytokine can alter brain function, resulting in a variety of 'illness responses' including increased sleep, decreased fo...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(95)00715-3
更新日期:1995-09-18 00:00:00
abstract::Immunohistochemical localization of brain-derived neurotrophic factor (BDNF) in the monkey brain was investigated using a polyclonal anti-BDNF antibody produced in our laboratory. The antibody recognized a single band in monkey brain homogenates, and the estimated molecular weight was approximately 14 kDa, which corre...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(99)01082-3
更新日期:1999-03-13 00:00:00
abstract::The effect of intracerebroventricular (i.c.v.) infusion of various iso- and hypertonic saccharide solutions on water intake stimulated by intracarotid (i.c.) infusion of hypertonic NaCl was studied in sheep. Without an i.c.v. infusion, water intake during a 10-min period following an i.c. infusion of 4 M NaCl (1.4 ml/...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(89)91006-8
更新日期:1989-07-24 00:00:00
abstract::Electrophysiological studies using rats were performed to examine the influence of locus coeruleus (LC) on nucleus accumbens (Acc) neurons. Spike generation by hippocampal stimulation was inhibited by both LC conditioning stimulation and iontophoretic application of noradrenaline, but spikes elicited by stimulation of...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(85)90172-6
更新日期:1985-07-15 00:00:00
abstract::With the use of [3H]p-aminoclonidine (PAC), alpha 2-adrenergic binding sites were mapped in the brain of the Japanese quail (Coturnix coturnix japonica). The sites were labeled with the use of in vitro quantitative autoradiography. Special attention was given to areas implicated in the control of sexually dimorphic re...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(89)90088-7
更新日期:1989-07-03 00:00:00