Abstract：
:We examined the effect of CP-154,526 on cardiovascular changes elicited in conscious rabbits by stressful stimuli (loud sound, cage move, pinprick, formaldehyde vapour and air-jet stress). CP-154,526 substantially reduced pressor and heart rate responses to these stimuli (both vagally and sympathetically mediated), and reduced QT shortening during air-jet stress. Blocking of central CRF1 receptors attenuates cardiovascular responses to environmental stimuli, presumably by affecting brain centres that control cardiovascular functions.
journal_name
Brain Resjournal_title
Brain researchauthors
Nalivaiko E,Blessing WWdoi
10.1016/j.brainres.2004.05.062subject
Has Abstractpub_date
2004-08-13 00:00:00pages
234-7issue
1-2eissn
0006-8993issn
1872-6240pii
S0006899304008443journal_volume
1017pub_type
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