Osmotic stimulation induces changes in the expression of beta-adrenergic receptors and nuclear volume of astrocytes in supraoptic nucleus of the rat.

abstract：:These experiments examine the dependence of medial hypothalamic alpha 2-receptor binding on the availability of circulating glucose. Food deprivation and tolbutamide-induced hypoglycemia both diminished alpha 2-binding. These binding results were highly correlated with serum glucose levels. Prevention of tolbutamide h...

journal_title：Brain research

authors： Chafetz MD,Parko K,Diaz S,Leibowitz SF

更新日期：1986-10-08 00:00:00

abstract：BACKGROUND:Diminished dopaminergic neurotransmission contributes to decreased reward and negative eating behaviors in obesity. Bariatric surgery is the most effective therapy for obesity and rapidly reduces hunger and improves satiety through unknown mechanisms. We hypothesized that dopaminergic neurotransmission would...

journal_title：Brain research

authors： Dunn JP,Cowan RL,Volkow ND,Feurer ID,Li R,Williams DB,Kessler RM,Abumrad NN

更新日期：2010-09-02 00:00:00

abstract：:Five pairs of neurosecretory cells in the subesophageal ganglion of the silkmoth Bombyx mori discharge action potentials in (near) synchrony to release a pheromone biosynthesis-activating neuropeptide (PBAN). Waveforms of compound action potentials recorded extracellularly from axonal tracts were analyzed to determine...

journal_title：Brain research

authors： Ichikawa T

更新日期：2002-03-08 00:00:00

abstract：:In an attempt to determine the basis for apparently conflicting reports of the effects of noradrenaline (NA) on the neurohypophyseal system and its effects on the parvocellular periventricular region of the paraventricular nucleus (PVN), recordings were made from the neurons in the supraoptic nucleus (SON) and the per...

journal_title：Brain research

authors： Inenaga K,Dyball RE,Okuya S,Yamashita H

更新日期：1986-03-26 00:00:00

abstract：:In the present functional magnetic resonance imaging (fMRI) study, we aimed to evaluate whether distinct regions of the hippocampus were associated with spatial memory for items presented in different locations of the visual field. In Experiment 1, during the study phase, participants viewed abstract shapes in the lef...

journal_title：Brain research

authors： Jeye BM,MacEvoy SP,Karanian JM,Slotnick SD

更新日期：2018-05-15 00:00:00

abstract：:The present study was undertaken in order to study the rate of maturation of the cochlear action potential sensitivity, latency, and tuning curves for various stimulus frequencies and to correlate the development of latency and frequency selectivity with threshold development. This study showed a two-stage model of ma...

journal_title：Brain research

authors： Puel JL,Uziel A

更新日期：1987-12-15 00:00:00

abstract：:Benzodiazepine (BZ) site ligands affect vigilance, anxiety, memory processes, muscle tone and epileptogenic propensity through modulation of neurotransmission at GABA(A) receptors containing alpha1, alpha2, alpha3 or alpha5 subunits, and may have numerous experimental and clinical applications. The ability of non-sele...

journal_title：Brain research

authors： Savić MM,Clayton T,Furtmüller R,Gavrilović I,Samardzić J,Savić S,Huck S,Sieghart W,Cook JM

更新日期：2008-05-07 00:00:00

abstract：:It has been confirmed that gabapentin (GBP) induced a inhibition of the voltage-gated persistent sodium current in chronically compressed dorsal root ganglion (DRG) neurons. The persistent sodium current is found in excitable DRG neurons of painful diabetic neuropathy (PDN) rats where it is mediated by tetrodotoxin (T...

journal_title：Brain research

authors： Zhang JL,Yang JP,Zhang JR,Li RQ,Wang J,Jan JJ,Zhuang Q

更新日期：2013-02-01 00:00:00

abstract：:When N-methyl-D,L-aspartic acid was injected into the A5 catecholamine cell group of the rat, a dose-dependent decrease in blood pressure and heart rate was obtained. These cardiovascular changes were subsequently blocked by the (-) and (+) isomers of the aspartate receptor blocker 2-amino-5-phosphonovalerate (2-amino...

journal_title：Brain research

authors： Close JM,Neil JJ,Loewy AD

更新日期：1982-10-14 00:00:00

abstract：:In a study of the capacity of neural grafts to promote functional recovery in rats with fimbria-fornix lesions, 5 groups of rats were studied behaviourally and with acetylcholinesterase (AChE) histochemistry: (1) sham-operated controls; (2) bilateral fimbria-fornix lesions; (3) bilateral lesions plus bilateral solid e...

journal_title：Brain research

authors： Dunnett SB,Low WC,Iversen SD,Stenevi U,Björklund A

更新日期：1982-11-18 00:00:00

abstract：:The ability of diphenylhydantoin (DPH) to protect against hypoxia-induced neuronal damage was examined using electrophysiological recordings of extracellular evoked potentials from CA1 pyramidal neurons of rat hippocampal slices in vitro. In normal medium, a 15-min hypoxic insult (95% N2/5% CO2) produced rapid and com...

journal_title：Brain research

authors： Stanton PK,Moskal JR

更新日期：1991-04-19 00:00:00

abstract：:Simulated networks of excitatory and inhibitory neurons have previously been shown to reproduce critical features of experimental data regarding neural coding in V1, such as a positive relationship between thalamic input spike rate and the power of gamma frequency oscillations. This effect, referred to as modulated ga...

journal_title：Brain research

authors： McDonnell MD,Mohan A,Stricker C,Ward LM

更新日期：2012-01-24 00:00:00

abstract：:Developmental delay, cognitive impairment, and refractory epilepsy are the most frequent consequences found in patients suffering from malformations of cortical development (MCD). However, therapeutic options for these psychiatric and neurological comorbidities are currently limited. The development of white matter un...

journal_title：Brain research

authors： Ma L,Yang F,Zhao R,Li L,Kang X,Xiao L,Jiang W

更新日期：2015-10-05 00:00:00

abstract：:This study is focused to learn about the cellular localization of transcription factors binding to the cAMP response element-CREBs-in the brain of normal rats and in animals subjected to excitotoxic cell damage. For this purpose, CREB-1 and CREB-2 immunoreactivity is examined in the developing and adult rat brain unde...

journal_title：Brain research

authors： Ferrer I,Blanco R,Rivera R,Carmona M,Ballabriga J,Olivé M,Planas AM

更新日期：1996-03-11 00:00:00

abstract：:Alterations in neurotrophic signaling pathways may contribute to the changes in the mesolimbic dopamine system induced by chronic morphine exposure. In a rat model of morphine dependence, we previously identified increased levels of phospholipase C gamma-1 (PLCgamma1) immunoreactivity specifically within the ventral t...

journal_title：Brain research

authors： Wolf DH,Nestler EJ,Russell DS

更新日期：2007-07-02 00:00:00

abstract：:Rab3A is a small GTP-binding synaptic vesicle protein, shown to dissociate from synaptic vesicle membranes upon depolarization-induced exocytosis. Using an antiserum raised against rab3A, we found that the antigen was localized to the neuropil of specific brain regions, but was not present in major fiber tracts or mos...

journal_title：Brain research

authors： Moya KL,Tavitian B,Zahraoui A,Tavitian A

更新日期：1992-09-11 00:00:00

abstract：:The relationship between fiber tract formation and transverse and longitudinal borders of the diencephalon was investigated in Alligator embryos beginning when this structure was a single unit and continuing until internal subgroups were present within individual segments. At all stages of development, distinct bundle...

journal_title：Brain research

authors： Pritz MB

更新日期：2010-02-08 00:00:00

abstract：:Rhesus monkeys were taught to make identical wrist flexion and extension movements in response to either a visual cue or to vibratory cues. Changes in firing rates that were not stimulus-associated but preceded the movements were measured for each primary somatosensory cortical neuron recorded under the two stimulus c...

journal_title：Brain research

authors： Nelson RJ,Douglas VD

更新日期：1989-04-10 00:00:00

abstract：:Cytochemistry was used to examine the distribution of two pathways of utilization of hydrogen (Type I and Type II H) generated by glucose-6-phosphate dehydrogenase (G6PD) in circumventricular organs (CVOs) and the hypothalamo-neurohypophysial system in cryostat sections of rat brain. Type I H is defined as that portio...

journal_title：Brain research

authors： Summy-Long JY,Salisbury R,Marietta MP,Hartman RD,Weisz J

更新日期：1984-02-27 00:00:00

abstract：:Early adverse events have been shown to increase the incidence of interstitial cystitis/painful bladder syndrome in adulthood. Despite high clinical relevance and reports of stress-related symptom exacerbation, animal models investigating the contribution of early life stress to female urological pain are lacking. We ...

journal_title：Brain research

authors： Pierce AN,Di Silvestro ER,Eller OC,Wang R,Ryals JM,Christianson JA

更新日期：2016-05-15 00:00:00

abstract：:The localization of the two Ca-activated extralysosomal proteases m-calpain and mu-calpain in the eye of the adult rabbit was examined by immunohistochemistry, using poly- and monoclonal antibodies against the corresponding rabbit antigens. Immunoreactivity against the two forms of calpains was observed in the epithel...

journal_title：Brain research

authors： Persson H,Kawashima S,Karlsson JO

更新日期：1993-05-21 00:00:00

abstract：:Kallikrein hydrolyzes various biologically active peptides, other than kininogens, such as vasoactive intestinal polypeptide (VIP), in vitro. Since kallikrein and VIP have been immunohistochemically shown to be present in the perivascular areas of the pineal gland, this study was designed to determine their topographi...

journal_title：Brain research

authors： Kudo M,Yamazaki I,Suzuki T,Ebihara Y,Iwadate H,Kizuki K

更新日期：1998-06-29 00:00:00

abstract：:Circumstantial evidence suggests that binding sites for the plant lectin Bandeiraea simplicifolia I-isolectin B(4) are expressed by nociceptive primary sensory neurones. In order to test this hypothesis directly, we have used a combination of intracellular staining of functionally characterised primary sensory neurone...

journal_title：Brain research

authors： Gerke MB,Plenderleith MB

更新日期：2001-08-17 00:00:00

abstract：:Huntington׳s Disease (HD) is a fatal neurodegenerative disorder caused by expanded polyglutamine repeats in the Huntingtin (HTT) gene. While the gene was identified over two decades ago, it remains poorly understood why mutant HTT (mtHTT) is initially toxic to striatal medium spiny neurons (MSNs). Models of HD using n...

journal_title：Brain research

authors： Mattis VB,Svendsen CN

更新日期：2017-02-01 00:00:00

abstract：:Afferent pathways innervating the urinary bladder consist of myelinated Adelta- and unmyelinated C-fibers, the neuronal cell bodies of which correspond to medium and small-sized cell populations of dorsal root ganglion (DRG) neurons, respectively. Since hyperpolarization-activated cyclic nucleotide-gated cation (HCN) ...

journal_title：Brain research

authors： Matsuyoshi H,Masuda N,Chancellor MB,Erickson VL,Hirao Y,de Groat WC,Wanaka A,Yoshimura N

更新日期：2006-11-13 00:00:00

abstract：:The amide-type local anesthetic (LA) lidocaine activates transient receptor potential (TRP) ankyrin-1 (TRPA1) channels to facilitate spontaneous l-glutamate release onto spinal substantia gelatinosa (SG) neurons, which play a crucial role in regulating nociceptive transmission. In contrast, the ester-type LA procaine ...

journal_title：Brain research

authors： Piao LH,Fujita T,Yu T,Kumamoto E

更新日期：2017-02-15 00:00:00

abstract：:In a previous study, male rats showed behavioural deficits after a single restraint stress but not after 5 daily restraint periods (i.e. adaptation had developed): female rats although less affected by single restraint failed to adapt over the same time course. This sex difference was associated with the male but not ...

journal_title：Brain research

authors： Haleem DJ,Kennett G,Curzon G

更新日期：1988-08-23 00:00:00

abstract：:Peroxisome proliferator-activated receptor gamma (PPAR-gamma) has been described to have a role in the modulation of various genes involved in Abeta homeostasis, inflammation, and energy metabolism, making it a candidate gene for risk of Alzheimer's disease (AD). A functional polymorphism in exon 2 of the PPAR-gamma g...

journal_title：Brain research

authors： Yao L,Li K,Zhang L,Yao S,Piao Z,Song L

更新日期：2009-09-29 00:00:00

abstract：:The object of this study was to quantify and compare the degree of control monkeys may assert over firing patterns of normal and epileptic neurons. Thirty-seven epileptic and 70 normal neurons were studied in detail. The operant task was for the monkey to generate specified consecutive interspike intervals (ISI). The ...

journal_title：Brain research

authors： Wyler AR,Finch CA,Burchiel KJ

更新日期：1978-08-04 00:00:00

abstract：:The effects of caffeine ingestion and exposure to bright light, both separately and in combination, on salivary melatonin and tympanic temperature were assessed in humans. Four treatments during a 45.5 h sleep deprivation period were compared: Dim Light-Placebo, Dim Light-Caffeine, Bright Light-Placebo and Bright-Ligh...

journal_title：Brain research

authors： Wright KP Jr,Badia P,Myers BL,Plenzler SC,Hakel M

更新日期：1997-01-30 00:00:00