Abstract：
:Five pairs of neurosecretory cells in the subesophageal ganglion of the silkmoth Bombyx mori discharge action potentials in (near) synchrony to release a pheromone biosynthesis-activating neuropeptide (PBAN). Waveforms of compound action potentials recorded extracellularly from axonal tracts were analyzed to determine the firing activity, timing of spikes and the combination of active cells. Analyses revealed a heterogeneous cellular organization of the neurosecretory cell system. There was a gradient in the firing activity among the cells and the activity of a cell was closely related to relative timing of firing: the most active cell was usually the first to fire and participated in about 90% of all synchronous firing events, while the least active unit was mostly the last to fire and contributed to only 40% of all firing events. A cell with a higher firing activity had a higher potential to mediate propagation of synchronous firing in the cell system. Firing activities of right and left cell groups usually differed and the difference increased in case of a low temperature. Synchronous firings occurred more frequently among the same subgroup of cells rather than different subgroups. Heterogeneous cellular organization and coupling may be important for producing a graded pattern of active cell numbers, which seems to be suitable for maintaining a stable firing (secretory) activity of the cell system for a long period of time.
journal_name
Brain Resjournal_title
Brain researchauthors
Ichikawa Tdoi
10.1016/s0006-8993(01)03349-2subject
Has Abstractpub_date
2002-03-08 00:00:00pages
156-65issue
2eissn
0006-8993issn
1872-6240pii
S0006899301033492journal_volume
929pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract：:Cytogenesis in the kitten retina has been investigated with [3H]thymidine autoradiography and a stain for mitotic figures. The nuclei of cells in S-phase are located adjacent to the inner margin of the cytoblast layer, near the inner plexiform layer. The nuclei then migrate toward the outer limiting membrane (OLM) to ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0165-3806(85)90235-4
更新日期：1985-03-01 00:00:00
abstract：:The hypothalamic response area for electrically induced locomotion was determined using moveable electrodes and discriminant analysis as an appropriate statistical technique. At 241 out of 641 stimulated sites locomotion was induced. The distribution of locomotion sites is relatively diffuse. Discriminant analysis of ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(88)91045-1
更新日期：1988-05-24 00:00:00
abstract：:We examined the brain uptake of prostaglandin D2 after its i.v. administration to mice. The determination of this prostaglandin in tissues was performed by a sensitive and rapid radioimmunoassay after purification of the prostaglandin by high-performance liquid chromatography. When 1.0 mg/kg of prostaglandin D2 was in...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(86)91079-6
更新日期：1986-10-22 00:00:00
abstract：:We have explored the potential neuroprotective effect of local lentiviraly-mediated overexpression of nerve growth factor (NGF) on in vivo long-term potentiation (LTP) in the rat hippocampus under pathological conditions. The suspension of lentiviral particles was prepared using a genetic construct containing the huma...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2015.07.051
更新日期：2015-10-22 00:00:00
abstract：:Several neurodevelopmental disorders, including schizophrenia, autism, ADD/ADHD and dyslexia are believed to originate during gestation and involve white matter abnormalities. Modulation of glutamate environments and glutamate receptors has also been implicated in alteration of oligodendrocytes, the myelin forming cel...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2008.06.126
更新日期：2008-10-09 00:00:00
abstract：:In monkeys (Macaca fuscata and mulatta), horseradish peroxidase (HRP) was injected in the cerebral cortices, areas 4 (medial and lateral parts), 5, 6 and 9 (a part just rostral to area 6), in which stimulation of cerebellar nuclei was known to elicit superficial or deep thalamocortical responses. Retrogradely labelled...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(83)90698-4
更新日期：1983-09-12 00:00:00
abstract：:Cytotoxic effects of L-glutamate and related compounds were investigated on rat glioma C6 cells in vitro. Within 12-24 h, addition of glutamate to the culture medium, resulted in degeneration of the C6 cells. The ED50 for glutamate-induced damage was about 4 mM. Seventeen structural analogues of glutamate, including a...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(84)91222-8
更新日期：1984-06-15 00:00:00
abstract：:We investigated the effect of losartan, a nonpeptide angiotensin II (Ang II)-type 1 (AT1) receptor antagonist, on the responses evoked by Ang II and L-glutamate (L-Glu) in the rostral ventrolateral medulla (RVLM). Adult spontaneously hypertensive rats (SHR) and Wistar-Kyoto (WKY) rats were anesthetized with halothane ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(94)91344-7
更新日期：1994-12-05 00:00:00
abstract：:A 'new' and orderly representation of the body surface was found in the cerebral cortex of the cat. This somatotopic map was located in the anterior ectosylvian sulcus (AES), an area known to represent several modalities, but believed to be distinguished from primary sensory cortex by its lack of sensory topographies....
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(82)90207-4
更新日期：1982-03-04 00:00:00
abstract：:Mapping studies with central drug injections in the hungry rat have identified the perifornical lateral hypothalamus as being uniquely sensitive to the feeding suppressive effects of exogenous dopamine, as well as anorexic drugs which release endogenous catecholamines. In the present study, the hypothalamic dopamine-r...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(79)90899-0
更新日期：1979-08-17 00:00:00
abstract：:Many lines of evidence support the importance of the nucleus accumbens (NAC) for ethanol-reinforced behavior. The nature of the neuronal activity that occurs in this region during ethanol self-administration is not known. We recorded from ensembles of single-units primarily located within the shell of the NAC during o...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(98)01245-1
更新日期：1999-01-30 00:00:00
abstract：:Corticotropin-releasing factor (CRF) in the brain plays an important role in regulations of physiological and behavioral processes, yet CRF distribution in tree shrew brain has not been thoroughly and systematically reported. Here we examined the distribution of CRF immunoreactivity in the brain of tree shrews (Tupaia...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2015.06.004
更新日期：2015-08-27 00:00:00
abstract：:Retinae taken from embryonic mice were transplanted to the brain of newborn rats. One eye was removed from the recipients at this time to promote innervation of host visual centers. After 4-6 weeks the optic nerve of the remaining eye was transected to eliminate all visual afferents of host origin and 4-6 days later t...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(90)91338-h
更新日期：1990-11-19 00:00:00
abstract：:Using previously characterized polyclonal antibody directed against dopamine beta-hydroxylase (DBH), immunoreactive fibers were demonstrable in pineals of 6 controls of various ages and of 3 individuals with Alzheimer's disease (AD). Abnormal, swollen axons were present in pineals from aged individuals and from indivi...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(89)90818-4
更新日期：1989-03-06 00:00:00
abstract：:Mitochondrial division inhibitor (mdivi-1), a selective inhibitor of a mitochondrial fission protein dynamin-related protein 1 (Drp1), has been shown to exert protective effects in heart and cerebral ischemia-reperfusion models. The present study was designed to investigate the beneficial effects of mdivi-1 against sp...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2015.03.033
更新日期：2015-09-04 00:00:00
abstract：:We examined regional cerebral metabolic rates for glucose (rCMRglc) and brain incorporation coefficients (k*) of each of three intravenously infused fatty acid radiotracers, [9,10-(3H)]palmitate ([3H]PAM), [1-(14C)]arachidonate ([14C]AA) and [1-(14C)]docosahe-xaenoate ([14C]DHA), in awake rats fully kindled by once-da...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(96)00854-2
更新日期：1996-12-16 00:00:00
abstract：:The activities of tyrosine hydroxylase and dopamine-beta-hydroxylase were measured in the medial basal hypothalamus and remaining hyothalamic tissue of female rats at various times during diestrus 2, proestrus and estrus. Tyrosine hydroxylase activity in the medial basal hypothalamus was significantly lower at 12.00 h...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(80)90407-2
更新日期：1980-09-08 00:00:00
abstract：:While much has been elucidated about the hypothalamic controls of energy balance, the epidemic of obesity continues to escalate. Recent work has suggested that extra-hypothalamic central nervous system structures may play a previously un-appreciated role in the control of ingestive behavior and body weight regulation....
journal_title：Brain research
pub_type： 杂志文章,评审
doi：10.1016/j.brainres.2010.06.009
更新日期：2010-09-02 00:00:00
abstract：:Hippocampal CA1 pyramidal cell neurons are sensitized to depolarization by L-2-amino-4-phosphonobutanoic acid (L-AP4) following exposure to L-quisqualic acid (QUIS). It has been proposed that induction of this 'QUIS-effect' involves uptake of L-QUIS by hippocampal cells. We have used o-phthaldialdehyde (OPA) derivatiz...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)91359-z
更新日期：1993-03-05 00:00:00
abstract：:Previous research has suggested the potential involvement of the hypothalamic-pituitary-adrenal (HPA) axis in psychostimulant reinforcement. In particular, we have found significant correlations between electric footshock-induced increases in plasma corticosterone and the acquisition, or lack thereof, of intravenous c...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(96)00206-5
更新日期：1996-05-25 00:00:00
abstract：:A study was undertaken of the role of the external lateral parabrachial subnucleus (PBNLe) in flavor preferences induced by the intragastric administration of predigested/cephalic food. These preferences were developed using two different learning procedures, concurrent and sequential. In the concurrent procedure, two...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(02)03032-9
更新日期：2002-09-20 00:00:00
abstract：:Converging evidence suggests that compromised motor abilities in hemiparetic cerebral palsy are not solely due to impairments in motor execution, but are also related to deficits in action planning. The present study had two aims. First, we compared grip planning in a sequential task between participants with left-sid...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2008.12.074
更新日期：2009-03-19 00:00:00
abstract：:It is known that transmitter release depends upon the entry of calcium ions into the synaptic terminal. Mitochondria have been suggested to play a key role on the regulation of intracellular Ca2+ concentration, thereby influencing transmitter liberation and synaptic transmission. Here we report the stimulatory effect ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(80)90618-6
更新日期：1980-01-13 00:00:00
abstract：:Five normal rats and four rats with bilateral lesions of auditory cortex were tested by the conditioned suppression procedure to determine their abilities to discriminate between spatially separated sound sources. The discrimination involved detection of a change in location of a train of clicks from a speaker on the ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(78)90865-x
更新日期：1978-04-28 00:00:00
abstract：:The effects of infusing N-methyl-d-aspartate (NMDA) into the raphe nuclei on release of 5-HT in this brain region and also the frontal cortex of the same animal were studied using in vivo microdialysis in freely moving rats. Infusion of 25 microM NMDA into the raphe led to a substantial decrease in dialysate 5-HT in t...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(97)01333-4
更新日期：1998-02-09 00:00:00
abstract：:The effect of intraocular injection of the neurotoxin, kainic acid, on the retinofugal pathway has been examined by anterograde transport of horseradish peroxidase. Although less peroxidase was present in all the primary optic centers after the intraocular injection of kainic acid than in the controls, the area occupi...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(84)90939-9
更新日期：1984-01-09 00:00:00
abstract：:Aging leads to a decrease in the number of neurons expressing vasopressin (VP) and vasoactive intestinal polypeptide (VIP) in the suprachiasmatic nucleus (SCN) of the rat. Similar results were observed following prolonged alcohol consumption and withdrawal. In the latter circumstances, the administration of nerve grow...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2005.04.066
更新日期：2005-06-28 00:00:00
abstract：:The reversible blockade of geniculate PGO waves was carried out by localized cooling of the ponto-geniculate pathways during paradoxical sleep in chronic cats. In parallel, long-term recordings of unit activity were performed in non-specific visuooculomotor thalamic structures where no PGO waves occurred. Blockade of ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(77)90341-9
更新日期：1977-12-02 00:00:00
abstract：:Thermoregulation is a complex intercommunicative function requiring coordination between core body temperature (CBT), the central nervous system, and peripheral vasculature. In menopausal women, dysregulation of thermoregulatory mechanisms leads to hot flushes and night sweats. A previous study in ovariectomized (OVX)...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2006.09.050
更新日期：2006-12-06 00:00:00
abstract：:Several studies have examined the activity of neurons in hypothalamic tissue slices. The present experiments studied relationships between neuronal activity (firing rate and thermosensitivity) and tissue survival as a function of time and slice thickness. Rat hypothalamic tissue slices were sectioned at different thic...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(97)00671-9
更新日期：1997-11-28 00:00:00
