Abstract:
:Using previously characterized polyclonal antibody directed against dopamine beta-hydroxylase (DBH), immunoreactive fibers were demonstrable in pineals of 6 controls of various ages and of 3 individuals with Alzheimer's disease (AD). Abnormal, swollen axons were present in pineals from aged individuals and from individuals with AD. The pathology of noradrenergic axons in a structure innervated by the superior cervical ganglion suggests that peripheral noradrenergic systems may be affected in aging and in AD.
journal_name
Brain Resjournal_title
Brain researchauthors
Jengeleski CA,Powers RE,O'Connor DT,Price DLdoi
10.1016/0006-8993(89)90818-4subject
Has Abstractpub_date
1989-03-06 00:00:00pages
378-82issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(89)90818-4journal_volume
481pub_type
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