Somatosensory cortex: a 'new' somatotopic representation.


:A 'new' and orderly representation of the body surface was found in the cerebral cortex of the cat. This somatotopic map was located in the anterior ectosylvian sulcus (AES), an area known to represent several modalities, but believed to be distinguished from primary sensory cortex by its lack of sensory topographies. Auditory and visual cells were also found in the AES, but were not randomly intermixed with the somatic representation. These data, coupled with those from previous studies strongly suggest the necessity for a revision of the traditional distinctions between cortical regions.


Brain Res


Brain research


Clemo HR,Stein BE




Has Abstract


1982-03-04 00:00:00














  • Hypocretin/orexin in arousal and stress.

    abstract::Multiple lines of evidence indicate that hypocretin/orexin (HCRT) participates in the regulation of arousal and arousal-related process. For example, HCRT axons and receptors are found within a variety of arousal-related systems. Moreover, when administered centrally, HCRT exerts robust wake-promoting actions. Finally...

    journal_title:Brain research

    pub_type: 杂志文章,评审


    authors: Berridge CW,España RA,Vittoz NM

    更新日期:2010-02-16 00:00:00

  • Cysteamine-induced depletion of central somatostatin-like immunoactivity: effects on behavior, learning, memory and brain neurochemistry.

    abstract::The effects of a wide range of doses of systemically administered cysteamine were studied on locomotor behavior, passive avoidance memory, cortical and cerebrospinal fluid somatostatin-like immunoactivity and cortical levels of dopamine and norepinephrine. High doses of cysteamine (200 and 250 mg/kg s.c.) led to susta...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Haroutunian V,Mantin R,Campbell GA,Tsuboyama GK,Davis KL

    更新日期:1987-02-17 00:00:00

  • Effects of nucleus accumbens amphetamine on lateral hypothalamic brain stimulation reward.

    abstract::The effects of amphetamine were examined in a brain stimulation reward paradigm in which response rate was measured across a range of stimulation frequencies. Both low (0.0625 and 0.125 mg/kg) and high (1.0, 2.0 and 4.0 mg/kg) doses of systemic amphetamine decreased the stimulation frequency needed to sustain low rate...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Colle LM,Wise RA

    更新日期:1988-09-06 00:00:00

  • Time course of the elevation of nerve growth factor (NGF) content in the hippocampus and septum following lesions of the septohippocampal pathway in rats.

    abstract::Axotomy of cholinergic neurons in the medial septum-diagonal band and degeneration of their terminals in the hippocampus resulting from fornix-fimbria lesions induce elevation of NGF content in these two brain regions. Postlesion levels of cholinergic neuron-specific ChAT activity in the septum suggest that endogenous...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Gasser UE,Weskamp G,Otten U,Dravid AR

    更新日期:1986-06-25 00:00:00

  • Distribution of CaMKIIα expression in the brain in vivo, studied by CaMKIIα-GFP mice.

    abstract::To facilitate the study of the CaMKIIα function in vivo, a CaMKIIα-GFP transgenic mouse line was generated. Here, our goal is to provide the first neuroanatomical characterization of GFP expression in the CNS of this line of mouse. Overall, CaMKIIα-GFP expression is strong and highly heterogeneous, with the dentate gy...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Wang X,Zhang C,Szábo G,Sun QQ

    更新日期:2013-06-26 00:00:00

  • Sensitivity to seizure-like activity in Drosophila following acute hypoxia and hypercapnia.

    abstract::Human seizure disorders represent a heterogeneous collection of neuropathies, many of which are poorly understood. To investigate the etiology of seizure disorders, we have used a group of Drosophila mutants known as the bang-sensitive (BS) paralytics. The BS mutants exhibit seizure-like activity (SLA) following a wid...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Whelan J,Burke B,Rice A,Tong M,Kuebler D

    更新日期:2010-02-26 00:00:00

  • The prolonged hyperpolarizing afterpotential in an invertebrate photoreceptor: wavelength and ionic dependence.

    abstract::A single electrode voltage clamp was used to examine the prolonged hyperpolarizing afterpotential (PHA) which accompanies photoconversion of a substantial fraction of rhodopsin (lambda max = 500 nM) to metarhodopsin (lambda max = 575 nM) in distal photoreceptor cells in the retina of the bay scallop, Pecten irradians....

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Cornwall MC,Gorman AL

    更新日期:1982-05-13 00:00:00

  • Immunocytochemical study on cholera toxin binding sites by monoclonal anti-cholera toxin antibody in neuronal tissue culture.

    abstract::An indirect method of immunocytochemistry showed that cholera toxin and its B-subunit served as specific neuronal surface markers in conjunction with monoclonal anti-cholera toxin and FITC labeled anti-mouse Fab. The cell types which get specifically stained in culture were peripheral neurons from dorsal root ganglion...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Okada E,Maeda T,Watanabe T

    更新日期:1982-06-24 00:00:00

  • Site of interaction of serotonin and desglycinamide-arginine-vasopressin in maintenance of ethanol tolerance.

    abstract::Rats trained to walk in a moving belt apparatus were subjected to a partial (fornix-fimbria (FF] or total (fornix-fimbria + cingulum bundles (FF + CB] chemical denervation of the dorsal serotonergic afferent pathways to the hippocampus. After chronic alcohol treatment that resulted in tolerance development to the moto...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Speisky MB,Kalant H

    更新日期:1985-02-11 00:00:00

  • Glutamate induces the expression and release of tumor necrosis factor-alpha in cultured hypothalamic cells.

    abstract::Tumor necrosis factor-alpha (TNFalpha) affects several CNS functions such as regulation of sleep, body temperature, and feeding during pathology. There is also evidence for TNFalpha involvement in physiological sleep regulation, e.g., TNFalpha induces sleep and brain levels of TNFalpha increase during prolonged wakefu...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: De A,Krueger JM,Simasko SM

    更新日期:2005-08-16 00:00:00

  • Protein synthesis requirement for the formation of synaptic elements.

    abstract::The formation of synapses in cell cultures of rat cerebellum was examined in the presence of the protein synthesis inhibitor cycloheximide. First, cell survival in the presence of 25 micrograms/ml cycloheximide was determined by phase contrast microscopy, trypan blue exclusion, total protein and uptake of [3H]gamma-am...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Burry RW

    更新日期:1985-09-30 00:00:00

  • Functions of the frontal cortex of the rat: a comparative review.

    abstract::This review summarizes the anatomical and functional organization of the frontal cortex of the rat in comparison to primates. Lesions of the primary motor or of the prefrontal cortex of both primates and rodents produce a consistent constellation of symptoms that are strikingly similar across species as diverse as rat...

    journal_title:Brain research

    pub_type: 杂志文章,评审


    authors: Kolb B

    更新日期:1984-11-01 00:00:00

  • Chloride-dependent pH regulation in connective glial cells of the leech nervous system.

    abstract::We used double-barreled pH-sensitive microelectrodes to study the mechanisms by which the intracellular pH is regulated in the connective glial cells of the medicinal leech. The experiments indicate that a Cl(-)- and HCO3(-)-dependent mechanism mediates some recovery from intracellular alkalosis even in the absence of...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Szatkowski MS,Schlue WR

    更新日期:1994-11-28 00:00:00

  • Binding of [3H]flunitrazepam and [3H]Ro5-4864 to crude homogenates of amygdala-kindled rat brain: two months post-seizure.

    abstract::The binding of [3H]flunitrazepam and [3H]Ro5-4864 to crude homogenates of amygdala-kindled and 'yoked' control rat brains was evaluated in subjects sacrificed 60 days after the sixth generalized convulsion. Decreases in the Bmax for [3H]flunitrazepam binding to 'central-type' benzodiazepine receptors were observed in ...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Burnham WM,Niznik HB,Okazaki MM,Kish SJ

    更新日期:1983-11-21 00:00:00

  • The sexually dimorphic nucleus of the hypothalamus contains GABA neurons in rat and man.

    abstract::The sexually dimorphic nucleus of the preoptic area (SDN-POA) is the most striking structure displaying a morphological sex difference in the rat brain. A potentially homologous nucleus has been identified in the human hypothalamus. The objective of the present study was to pursue the putative homology of the rat and ...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Gao B,Moore RY

    更新日期:1996-12-02 00:00:00

  • Evidence that L-type calcium channels do not contribute to static vestibular function in the guinea pig vestibular nucleus.

    abstract::Labyrinthine-intact guinea pigs received unilateral, brainstem cannula injections of (1) 2.5 micrograms of the selective dihydropyridine L-type Ca2+ channel agonist, Bay K 8644 (n = 4 animals); (2) 10 micrograms Bay K 8644 (n = 4); 12.5 micrograms of the selective dihydropyridine L-type Ca2+ channel antagonist, nifedi...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Sansom AJ,Smith PF,Darlington CL

    更新日期:1993-12-10 00:00:00

  • Peripheral input pathways projecting to the motor cortex in the cat.

    abstract::The possibility that the motor cortex receives peripheral input directly from the thalamus was examined using the evoked potential method and the following results were obtained. Potentials in the motor cortex evoked by stimulation of superficial radial (SR) or group II deep radial (DR) nerve were neither abolished no...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Asanuma H,Larsen KD,Zarzecki P

    更新日期:1979-08-24 00:00:00

  • A pharmacogenetic evaluation of the role of local anesthetic actions in the cocaine kindling process.

    abstract::Repeated administration of subconvulsant doses of lidocaine or cocaine results in the development of an increased susceptibility to seizures induced by the two drugs (pharmacological kindling). It has been hypothesized that the local anesthetic properties of cocaine are responsible for its convulsant and epileptogenic...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Marley RJ,Witkin JM,Goldberg SR

    更新日期:1991-10-25 00:00:00

  • Ibotenate-induced neuronal degeneration in immature rat brain.

    abstract::Stereotaxic microinjections of the excitotoxin, ibotenic acid, were made into the striatum, hippocampus or cerebellum of the immature (7-day-old) rat. Two days later, pups were decapitated and the brains processed for light microscopic examination or neurochemical analyses. 10 micrograms ibotenate caused a complete lo...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Steiner HX,McBean GJ,Köhler C,Roberts PJ,Schwarcz R

    更新日期:1984-07-30 00:00:00

  • Adaptive modeling of the unattended acoustic environment reflected in the mismatch negativity event-related potential.

    abstract::The mismatch negativity (MMN) event-related potential is elicited by changes in repetitive auditory stimuli. The present paper suggests that: (1) an acoustic model of the auditory environment is maintained even in the absence of attention focussed on auditory stimuli, preattentively detecting repetitive features of th...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Winkler I,Karmos G,Näätänen R

    更新日期:1996-12-02 00:00:00

  • Glucocorticoid receptor-immunoreactivity in corticotrophin-releasing factor afferents to the locus coeruleus.

    abstract::The stress-related neurohormone, corticotropin-releasing factor (CRF), also acts as a neurotransmitter to activate the brain noradrenergic nucleus, locus coeruleus (LC). Previous electrophysiological findings demonstrating that tonic CRF secretion in the LC is increased in adrenalectomized rats suggest that activity o...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Lechner SM,Valentino RJ

    更新日期:1999-01-16 00:00:00

  • CRF1 receptor antagonist CP-154,526 reduces cardiovascular responses during acute psychological stress in rabbits.

    abstract::We examined the effect of CP-154,526 on cardiovascular changes elicited in conscious rabbits by stressful stimuli (loud sound, cage move, pinprick, formaldehyde vapour and air-jet stress). CP-154,526 substantially reduced pressor and heart rate responses to these stimuli (both vagally and sympathetically mediated), an...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Nalivaiko E,Blessing WW

    更新日期:2004-08-13 00:00:00

  • Mechanism of the re-entrainment of the circadian rhythm in the rat pineal N-acetyltransferase activity to an eight-hour advance of the light-dark cycle: phase-jump is involved.

    abstract::During the re-entrainment of the rat pineal N-acetyltransferase (NAT) rhythm to an 8-h advance of a light-dark (LD) cycle accomplished by shortening of one dark period, the advanced light period phase-delayed the evening NAT rise and phase-advanced the morning decline. The phase-relationship between the rise and the d...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Illnerová H

    更新日期:1989-08-14 00:00:00

  • Comparison processes in category learning: from theory to behavior.

    abstract::Recent studies stressed the importance of comparing exemplars both for improving performance by artificial classifiers as well as for explaining human category-learning strategies. In this report we provide a theoretical analysis for the usability of exemplar comparison for category-learning. We distinguish between tw...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Hammer R,Bar-Hillel A,Hertz T,Weinshall D,Hochstein S

    更新日期:2008-08-15 00:00:00

  • In vivo chronic lead exposure alters [3H]nitrendipine binding in rat striatum.

    abstract::The effect of lead as a neurotoxic agent has been associated with alterations in calcium metabolism. On this line, the present study shows that lead alters the characteristics of [3H]nitrendipine ([ 3H]NDP) binding to rat striatal membranes. In vitro, lead shares the action of calcium in enhancing [3H]NDP binding alth...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Rius RA,Lucchi L,Govoni S,Trabucchi M

    更新日期:1984-11-19 00:00:00

  • Thermal hyperalgesia and mechanical allodynia produced by intrathecal administration of the human immunodeficiency virus-1 (HIV-1) envelope glycoprotein, gp120.

    abstract::Astrocytes and microglia in the spinal cord have recently been reported to contribute to the development of peripheral inflammation-induced exaggerated pain states. Both lowering of thermal pain threshold (thermal hyperalgesia) and lowering of response threshold to light tactile stimuli (mechanical allodynia) have bee...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Milligan ED,Mehmert KK,Hinde JL,Harvey LO,Martin D,Tracey KJ,Maier SF,Watkins LR

    更新日期:2000-04-07 00:00:00

  • Transfer of accelerated presbycusis by transplantation of bone marrow cells from senescence-accelerated mice.

    abstract::Until now, there has been no effective therapy for chronic sensorineural hearing impairment. This study investigated the role of bone marrow cells (BMCs) in cochlear dysfunction. BALB/c mice (2 months of age), a non-presbycusis-prone mouse strain, were lethally irradiated and then transplanted with BMCs from SAMP1 mic...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Baba S,Iwai H,Inaba M,Kawamoto K,Omae M,Yamashita T,Ikehara S

    更新日期:2006-11-20 00:00:00

  • The population of the dorsal root ganglion cells which have central processes in ventral root and their immunoreactivity.

    abstract::Axonal transport of fluorescent dyes applied to the cut distal ends of rat L4 dorsal and ventral spinal roots was studied in order to characterize the population of dorsal root ganglion (DRG) neurons emitting axons entering the ventral root. Ca. 9% of DRG neurons, principally of small or medium size, can be labeled fr...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Fang XB

    更新日期:1987-02-03 00:00:00

  • Lateral parabrachial lesions impair intraperitoneal but not intraventricular methylscopolamine-induced taste aversion learning.

    abstract::The role of the lateral parabrachial area (lPB) in the acquisition of a delayed taste aversion learning task (TAL) was examined by delivering the peripherally acting aversive compound, methylscopolamine (MSP), through two different routes, intraperitoneal and intraventricular. Consistent with previous anatomical, beha...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Cubero I,Puerto A

    更新日期:2000-07-14 00:00:00

  • Non-oriented cells of the striate cortex activated during smooth pursuit eye movements and steady fixations in behaving monkeys.

    abstract::Extracellular recordings were carried out in the primary visual cortex of behaving monkeys. Neurons were activated by moving a visual stimulus on their receptive fields during periods of steady fixation and by moving their receptive fields (smooth pursuit eye movements) on a motionless visual stimulus. Regarding non-o...

    journal_title:Brain research

    pub_type: 杂志文章


    authors: Galletti C,Squatrito S,Battaglini PP,Maioli MG

    更新日期:1983-01-31 00:00:00