Synaptic inhibition of phrenic motoneurones evoked by stimulation of the superior laryngeal nerve.

Abstract:

:Synaptic responses evoked in phrenic motoneurones (PMNs) by stimulation of the superior laryngeal nerve (SLN) were analysed in anaesthetised cats. Stimulation of the SLN was followed by inhibition of ipsilateral phrenic nerve discharge with the latency of 9.5 +/- 2.3 ms (mean +/- S.D.) and hyperpolarizations of ipsilateral PMN membrane potentials (latency, 8.4 +/- 2.1 ms) which were observed after stimuli applied both during inspiration and expiration. During the injection of Cl ions, the hyperpolarizations were either reversed or flattened in all 28 tested PMNs, thus indicating a direct inhibition. The possibility that the inhibitory postsynaptic potentials are produced by segmental respiratory interneurones is discussed.

journal_name

Brain Res

journal_title

Brain research

authors

Bellingham MC,Lipski J,Voss MD

doi

10.1016/0006-8993(89)90530-1

subject

Has Abstract

pub_date

1989-05-08 00:00:00

pages

391-5

issue

2

eissn

0006-8993

issn

1872-6240

pii

0006-8993(89)90530-1

journal_volume

486

pub_type

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