Hippocampal kindling alters the concentration of glial fibrillary acidic protein and other marker proteins in rat brain.

Abstract:

:The effect of hippocampal kindling on neuronal and glial marker proteins was studied in the rat by immunochemical methods. In hippocampus, pyriform cortex and amygdala there was an increase in glial fibrillary acidic protein (GFAP), indicating reactive gliosis, and an increase in the glycolytic enzyme NSE, suggesting increased anaerobic metabolism. Neuronal cell adhesion molecule (NCAM) decreased in pyriform cortex and amygdala of kindled rats, indicating neuronal degeneration.

journal_name

Brain Res

journal_title

Brain research

authors

Hansen A,Jørgensen OS,Bolwig TG,Barry DI

doi

10.1016/0006-8993(90)90791-9

subject

Has Abstract

pub_date

1990-10-29 00:00:00

pages

307-11

issue

1-2

eissn

0006-8993

issn

1872-6240

pii

0006-8993(90)90791-9

journal_volume

531

pub_type

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