The enteric nervous system in tissue culture. II. Ultrastructural studies of cell types and their relationships.

Abstract:

:Tissue culture preparations of the myenteric plexus from the guinea pig taenia coli have been studied by electron microscopy. Three main cell types can be identified: neurons, enteric glial cells and fibroblasts. The ultrastructure of these cells resembles that of the same cells in situ. Neuronal processes form close associations with other neurons and glial cells, but not with fibroblasts. After extended periods in culture, neurons and glial cells form aggregates of cells which resemble ganglia of the myenteric plexus in situ, having a compact neuropil and synapses between neuronal elements. Aggregates are connected to each other by thick bundles of neurites. Vesicle-containing nerve profiles are common; the majority contain a predominance of small agranular vesicles, but some contain many large granular or large opaque vesicles; profiles may also contain variable mixtures of these kinds of vesicles.

journal_name

Brain Res

journal_title

Brain research

authors

Bałuk P,Jessen KR,Saffrey MJ,Burnstock G

doi

10.1016/0006-8993(83)90467-5

subject

Has Abstract

pub_date

1983-02-28 00:00:00

pages

37-47

issue

1

eissn

0006-8993

issn

1872-6240

pii

0006-8993(83)90467-5

journal_volume

262

pub_type

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