Abstract：
:With the aim of determining a possible role of the entorhinal cortex (EC) in the processing of olfactory information, its electrical activity was recorded during different types of odour sampling behaviour. The EC spontaneous field potentials (EEGs) were related to those recorded simultaneously from the more rostrally lying olfactory bulb (OB) and prepiriform cortex (PPC), using coherence functions. The coherence values are measures of coupling between two neuronal populations. Auto- and coherence spectra were characterized by a peak in the beta-band (35-36 Hz) and another in the 16-20 Hz band. For the beta-peak of the PPC-EC coherence it was shown that both the maximal values and the median frequency decrease during the first 0.5-1.0 s of a trial in a two-choice odour discrimination task. These transients differed significantly for CS+ and CS- trials. However, no such difference was observed during exploratory sniffing at the same pair of odorants. It was concluded that during sniffing the degree of coupling of the EC with the PPC depends on the behavioural context but not on the quality of the odorants. As regards the 16-20 Hz components it was shown, using bispectral analysis, that these components represent the 1/2 subharmonic of the beta-components. The subharmonic components were enhanced during the initiation of sniffing. This means that the neural networks of OB, PPC and EC have non-linear dynamic properties. These networks show different modes of oscillatory behaviour, characteristic of the restful state and of the active sniffing state. Theoretical implications of these experimental results are discussed. In conclusion, it was demonstrated that modulations with sniffing behaviour are present in the beta-EEG components and their subharmonics in the olfactory brain areas including the EC. This indicates that the latter is involved in processes of the evaluation of olfactory cues in relation to the animal's behaviour.
journal_name
Brain Resjournal_title
Brain researchauthors
Boeijinga PH,Lopes da Silva FHdoi
10.1016/0006-8993(89)91506-0subject
Has Abstractpub_date
1989-01-30 00:00:00pages
257-68issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(89)91506-0journal_volume
478pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract：:Endogenous long-duration burst-organizing potentials (driver potentials, DPs) generated by neurons in the lobster cardiac ganglion play a critical role in the ability of the system to generate rhythmic bursts of nerve impulses. The DPs are normally terminated by a voltage-dependent potassium current, but when this is ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)90854-g
更新日期：1993-04-23 00:00:00
abstract：:Experiments were carried out to determine if stimuli which augment preganglionic nerve activity to sympathetic neurons, and thereby cause trans-synaptic induction, increase the retrograde transport of nerve growth factor (NGF). It was found that nerve activity had no effect on retrograde transport of [125I]NGF. It was...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(79)90701-7
更新日期：1979-12-14 00:00:00
abstract：:β-Amyloid peptide (Aβ) plays a central role in the pathogenesis of Alzheimer׳s disease, but in lower amounts it is found in normal brains where it participates in physiological processes and probably regulates synaptic plasticity. This study investigated the effects of physiologically relevant concentrations of Aβ (1 ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2014.02.031
更新日期：2014-04-16 00:00:00
abstract：:Animal models of cerebral infarction are crucial to understanding the mechanisms of neuronal survival following ischemic brain injury and to the development of therapeutic interventions for victims of all types of stroke. Rodents have been used extensively in such research. One rodent model of stroke utilizes either p...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2005.02.021
更新日期：2005-04-25 00:00:00
abstract：:Patches excised from fields CA1 and CA3 of the hippocampus were used to study AMPA receptor responses to repetitive application of brief pulses of agonist. AMPA receptors in field CA1 exhibited a larger degree of paired-pulse depression and a slower recovery rate from desensitization than those from CA3 patches. Respo...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(96)00030-3
更新日期：1996-04-15 00:00:00
abstract：:Oxidative stress plays an important role in the pathogenesis of neurodegeneration after the acute central nervous system injury. We reported previously that increased nitric oxide (NO) production following spinal cord hemisection tends to lead to neurodegeneration in neurons of the nucleus dorsalis (ND) that normally ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2005.07.003
更新日期：2005-09-07 00:00:00
abstract：:This study has examined the retinal synapses of the cat superior colliculus using electron microscope autoradiography and morphometric techniques. The depth of each retinal synapse was measured using a computer-based EM plotter. The area, perimeter, and synapse contact density of selected synapses were calculated usin...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(83)90130-0
更新日期：1983-06-20 00:00:00
abstract：:Early environmental factors can modulate the development of the hypothalamic-pituitary-adrenal (HPA) axis response to stress, together with subsequent brain functions and emotional behaviors. Two rat strains, Sprague-Dawley (SD) and Fischer 344 (F344), are known to exhibit differences in HPA axis reactivity and anxiet...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2009.11.070
更新日期：2010-02-26 00:00:00
abstract：:The development of bombesin-like peptides and their receptors was determined in 9 different rat brain regions. The concentration of immunoreactive bombesin increased dramatically in all brain regions examined during the third week after birth. In contrast, the density of [125I-Tyr4]bombesin binding sites was near maxi...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0165-3806(84)90107-x
更新日期：1984-08-01 00:00:00
abstract：:The senescence-accelerated mouse prone 8 (SAMP8) is a novel aging model characterized by early onset and rapid advancement of senescence. In the present study, 6-month-old male SAMP8 mice were orally administered icariin (75, 150mg/kg) for 15weeks. Mice were submitted to passageway water maze test and step-down passiv...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2010.03.084
更新日期：2010-06-02 00:00:00
abstract：:Our recent results showed that angiotensin II or III (AII, AIII) microinjected into the zona incerta (ZI) significantly increased water intake. The most effective doses of AII and AIII were also defined. The two neuropeptides had their effects differently on drinking via different receptors. AII bound to AT(1) that wa...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2004.01.002
更新日期：2004-03-26 00:00:00
abstract：:The acute stroke phase is a critical time frame used to evaluate stroke severity, therapeutic options, and prognosis while also serving as a major tool for the development of diagnostics. To further understand stroke pathophysiology and to enhance the development of treatments, our group developed a translational pig ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2020.146778
更新日期：2020-06-01 00:00:00
abstract：:Previous studies have reported that schizophrenia (SZ) patients showed selective reinforcement learning deficits and abnormal feedback-related event-related potential (ERP) components. However, how the brain networks and their topological properties evolve over time during transient feedback-related cognition processi...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2020.146979
更新日期：2020-11-01 00:00:00
abstract：:The disector method was used to estimate the numerical density of neurons (number per unit volume) and their actual number per column (number under a given area of pial surface), in the occipital (monocular segment of the primary visual area, Oc1M), the parietal (somatosensory barrelfield area, Par1) and the frontal c...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)90884-p
更新日期：1993-04-23 00:00:00
abstract：:Using in vivo microdialysis, we examined the ability of choline (Ch) chloride (120 mg/kg i.p.) to amplify basal and stimulated acetylcholine (ACh) release from rat striatum in the presence of high (10(-5) M) and low (5 x 10(-8) M) neostigmine concentration. High concentrations might suppress ACh release, and thus Ch d...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)91330-u
更新日期：1993-12-03 00:00:00
abstract：:The pedunculopontine tegmental nucleus (PPT) has been implicated in the generation and/or maintenance of both active sleep (AS) and wakefulness (W). GABAergic neurons are present within this nucleus and recent studies have shown that these neurons are active during AS. In order to examine the role of mesopontine GABAe...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(02)02475-7
更新日期：2002-07-19 00:00:00
abstract：:We utilized nylon arrays to measure gene expression in mouse brains after various postmortem intervals (PMIs). Gene expression after overnight refrigeration or 4 h at room temperature then overnight refrigeration correlated highly and approximately equivalently to that in brains processed immediately. After 8-24 h at ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(02)02644-6
更新日期：2002-06-28 00:00:00
abstract：:The effects of a conditioning lesion on the rate of sudomotor axon regeneration were judged by the recovery of sweat gland (SG) secretion after cholinergic stimulation. Three groups of mice were given a conditioning lesion by crushing the sciatic nerve at mid-thigh 4, 7, and 14 days before a test lesion. A 4th group r...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(90)90547-o
更新日期：1990-02-19 00:00:00
abstract：:The effects of 4 anaesthetics, halothane, alpha-chloralose, chloral hydrate and pentobarbitone, on rat striatal extracellular dihydroxyphenylacetic acid (DOPAC) levels were determined using in vivo voltammetry. Stable baseline levels of DOPAC were maintained under halothane/N2O and alpha-chloralose while the extracell...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(86)90270-2
更新日期：1986-07-30 00:00:00
abstract：:To date several circuities in supraspinal site of the central nervous system have been known to engage in pain modulation. Lateral hypothalamus (LH) is known as part of the circuit of pain modulation among supraspinal sites. Its role in several animal pain models has been well defined. In this study, we examined the r...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2020.146674
更新日期：2020-04-01 00:00:00
abstract：:Glycine is taken up twice as rapidly by neurons R3-R14 as by other identified neurons in the Aplysia parietovisceral ganglion. Earlier studies had shown that R3-R14 have much higher glycine concentrations than other Aplysia neurons. Most of the glycine taken up by R3-R14 was biochemically untransformed for at least 1 ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(78)91049-1
更新日期：1978-10-06 00:00:00
abstract：:In the past few years a steadily increasing number of substances have been suggested to qualify as sleep-inducing factors. Most 'sleep factors' appear to exert their effects on slow-wave sleep. Recently, however, it has been shown that the cerebrospinal fluid (CSF) of sleep-deprived cats may contain a rapid eye moveme...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(86)91561-1
更新日期：1986-10-15 00:00:00
abstract：:Diverse neuropsychiatric diseases were recently linked to specific anti-neuronal autoantibodies targeting synaptic proteins. Symptoms can range from epileptic seizures to cognitive impairment to movement disorders, commonly responding to treatment with immunotherapy. Several of these autoantibodies target inhibitory s...
journal_title：Brain research
pub_type： 杂志文章,评审
doi：10.1016/j.brainres.2018.09.009
更新日期：2018-12-15 00:00:00
abstract：:The distribution of S-100-immunoreactive material was examined in the central nervous system of the gastropod snail. Helix pomatia, and electrophysiological properties of S-100-positive neurons were characterized. Immunocytochemical studies revealed S-100-like protein to be present in neurons localized in the cerebral...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(95)01584-1
更新日期：1996-04-15 00:00:00
abstract：:The morphological characteristics, distribution and neurochemical phenotype of striatal neuronal subtypes expressing the GABA(A) receptor alpha3-subunit were investigated using immunocytochemical and immunofluorescent techniques with an antibody specific for this subunit. alpha3-immunopositive neurons were infrequent ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(00)02636-6
更新日期：2000-09-08 00:00:00
abstract：:Within 5 days after reduction of activity of the rat soleus muscle, there was remodelling of the neuromuscular junction. Post-synaptic clefts were shorter, wider, and flatter, whereas nerve terminals showed sprouting and longitudinal distortion. The results, which differ from those found after denervation or total dis...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(86)90039-9
更新日期：1986-09-24 00:00:00
abstract：:Inorganic mercury (Hg2+) reduced voltage-gated calcium channel currents irreversibly in two different preparations. In cultured rat dorsal root ganglion (DRG) neurons, studied with the whole cell patch clamp technique, a rapid concentration-dependent decrease in the L/N-type currents to a steady state was observed wit...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)91146-j
更新日期：1993-12-31 00:00:00
abstract：:This study was designed to describe renal afferent information with respect to its intraspinal projections, convergence with cutaneous inputs, ascending projections, and modulation by descending fiber tracts. Extracellular recordings were made from neurons in the spinal gray while electrically stimulating the renal ne...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(88)91292-9
更新日期：1988-04-12 00:00:00
abstract：:Regulation of tyrosine hydroxylase (TH) by second messenger pathway activators was examined in rat olfactory bulb cell cultures. The number of TH-immunoreactive neurons was increased 2-3-fold by 36 h treatments with forskolin (Fsk, 10(-6) M) or phorbol myristate acetate (PMA, 10(-7) M), but was not significantly incre...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(09)90015-4
更新日期：1994-09-26 00:00:00
abstract：:Dynamin-1 is a multi-domain GTPase that is crucial for the fission stage of synaptic vesicle recycling and vesicle trafficking. In this study, we constructed prokaryotic expression plasmids for the four functional domains of dynamin-1, which are pGEX-4T-2-PH, pGEX-4T-2-PRD, pGEX-4T-2-GED and pGEX-4T-2-GTPase. Glutathi...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2013.10.053
更新日期：2014-01-16 00:00:00
