Abstract：
:The development of bombesin-like peptides and their receptors was determined in 9 different rat brain regions. The concentration of immunoreactive bombesin increased dramatically in all brain regions examined during the third week after birth. In contrast, the density of [125I-Tyr4]bombesin binding sites was near maximal in all brain regions examined by the second postnatal week. These data indicate that the development of receptors precede bombesin-like peptide production.
journal_name
Brain Resjournal_title
Brain researchauthors
Gillati MT,Moody TWdoi
10.1016/0165-3806(84)90107-xsubject
Has Abstractpub_date
1984-08-01 00:00:00pages
286-9issue
2eissn
0006-8993issn
1872-6240journal_volume
317pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract：:Choline acetyltransferase (ChAT) and glutamic acid decarboxylase (GAD) activities were measured in various visual structures of the pigeon brain after long-term monocular deprivation followed by short-term binocular presence or absence of light stimulation. The short-term phase (45 min) was coupled with a 2-deoxygluco...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(82)91253-7
更新日期：1982-09-16 00:00:00
abstract：:We reported earlier that overnight change in explicit memory is positively related to the change in sleep spindle activity (between a control and a learning night). However, it remained unclear whether this effect was restricted to good memory performers and whether a general association of sleep spindles and a "sleep...
journal_title：Brain research
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.brainres.2007.10.106
更新日期：2008-01-29 00:00:00
abstract：:Parkinson's disease (PD) is a common neurodegenerative disease characterized by progressive loss of midbrain dopaminergic neurons. To gain an insight into the mechanisms underlying the progression of PD, gene expression analysis was performed using two different brain regions, the substantia nigra pars compacta (SN) a...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2010.05.066
更新日期：2010-07-30 00:00:00
abstract：:As previously demonstrated, spontaneously firing bulbar inspiratory neurones are periodically inhibited either at the beginning of, or throughout expiration, while bulbar expiratory neurones are inhibited during inspiration. The aim of the present study was to test the hypothesis that amino acids act as transmitters o...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(82)90447-4
更新日期：1982-04-15 00:00:00
abstract：:The trisomy-16 mouse is considered to be a model of human trisomy-21 (Down syndrome). We have examined the electrical membrane properties of cultured dorsal root ganglion (DRG) neurons from normal and trisomy-16 fetuses. Trisomy-16 neurons had significantly accelerated rates of action potential depolarization and repo...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(89)90678-1
更新日期：1989-04-17 00:00:00
abstract：:Electrical activities of thin hippocampal sections of the guinea pig were studied in vitro during and after administration of black widow spider venom (BSV). In CA3 neurons, BSV induced spontaneous discharges which were suppressed by Co2+ or Mn2+. During BSV administration, trains of potential changes resembling excit...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(82)90103-2
更新日期：1982-07-29 00:00:00
abstract：:Previous studies have shown that chronic morphine increases levels of the G-protein subunits Gia and Goa, adenylate cyclase, cyclic AMP-dependent protein kinase, and certain phosphoproteins in the rat locus coeruleus, but not in several other brain regions studied, and that chronic morphine decreases levels of Gia and...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(91)91111-d
更新日期：1991-05-10 00:00:00
abstract：:Estrogens exert a wide variety of actions on reproductive and non-reproductive functions. These effects are mediated by slow and long lasting genomic as well as rapid and transient non-genomic mechanisms. Besides the host of studies demonstrating the role of genomic actions at the physiological and behavioral level, m...
journal_title：Brain research
pub_type： 杂志文章,评审
doi：10.1016/j.brainres.2006.07.098
更新日期：2006-12-18 00:00:00
abstract：:Stroke is the third leading cause of death in the US, with a prevalence of 750,000 patients per year, and a social cost estimated at $50 billion. Current therapeutics are targeted at restoring blood flow rather than on preventing the actual mechanisms associated with neuronal cell death. Here, we show that, following ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(02)02922-0
更新日期：2002-08-30 00:00:00
abstract：:The properties of 5 beta-reductase, 5 alpha-reductase and aromatase, 3 testosterone metabolizing enzymes, were studied in the quail brain by an in vitro incubation technique. The results describe the changes in time of metabolite production and the effects of temperature, enzyme and cofactor concentrations. The appare...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(84)91118-1
更新日期：1984-07-02 00:00:00
abstract：:Accumulating evidence suggests that the neuropeptide substance P (SP) and its principal receptor neurokinin 1 (NK1) play a specific role in the behavioral response to opioids and stress that may help to initiate and maintain addictive behavior. In animal models, the NK1 receptor is required for opioids to produce thei...
journal_title：Brain research
pub_type： 杂志文章,评审
doi：10.1016/j.brainres.2009.11.014
更新日期：2010-02-16 00:00:00
abstract：:Homer1a is implicated in depression in humans and depression-like behavior in mice. To further understand the role of Homer1a in stress-induced emotional changes, we applied very mild stress to Homer1a knockout (H1a KO) mice. The wild-type (WT) and H1a KO mice were restrained for 2h daily for 7 consecutive days at the...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2015.02.008
更新日期：2015-04-24 00:00:00
abstract：:Previous studies have demonstrated that increased mesolimbic dopamine (DA) activity disrupts sensorimotor gating as measured by prepulse inhibition (PPI) of the acoustic startle response (ASR) in rats. Other behavioral changes following mesolimbic DA activation are mediated through GABAergic efferent projections from ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(90)91754-5
更新日期：1990-11-05 00:00:00
abstract：:In rats kainic acid-induced seizures were accompanied by time-dependent cerebral cysteinyl-leukotriene (LT) and prostaglandin (PG) F2 alpha formation. Cysteinyl-LT were identified in the rat brain tissue extracts by their immunoreactive properties and their retention times upon reversed phase HPLC profiling. In perfus...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(90)90579-z
更新日期：1990-05-07 00:00:00
abstract：:The suprachiasmatic nuclei receive photic input information directly through a retinohypothalamic tract (RHT) and indirectly through a projection from the intergeniculate leaflet of the lateral geniculate complex, the geniculohypothalamic tract (GHT). Prior work has established that the RHT is sufficient for entrainme...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(88)90374-5
更新日期：1988-09-20 00:00:00
abstract：:It has recently been shown that the immunosuppressant cyclosporin A (CsA) dramatically ameliorates the selective neuronal necrosis which results from 10 min of forebrain ischemia in rats. Since CsA is a virtually specific blocker of the mitochondrial permeability transition (MPT) pore which is assembled under adverse ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(97)00005-x
更新日期：1997-04-04 00:00:00
abstract：:Sex hormone binding globulin (SHBG) is produced in brain where it is often co-localized with oxytocin. Infusions of SHBG into the medial preoptic area-anterior hypothalamus facilitate female sexual receptivity. SHBG has receptors on plasma membranes of the prostate gland where binding of the 5alpha-reduced androgen di...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(02)02956-6
更新日期：2002-09-06 00:00:00
abstract：:Immunohistochemical and retrograde tracing techniques were combined to demonstrate the occurrence of displaced ganglion cells (DGCs) exhibiting substance P-like immunoreactivity (SP-LI) in the pigeon retina. Following injections of rhodamine-labeled latex microspheres into the nucleus of the basal optic root (accessor...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(91)91159-x
更新日期：1991-04-12 00:00:00
abstract：:Basic fibroblast growth factor (FGF-2) isoforms of the adrenal medulla are differentially expressed during rat postnatal development. While the 18 and 23 kDa isoforms continuously rise towards the adult expression level, the 21 kDa isoform displays a peak expression at postnatal day 28. The peak expression of the 21 k...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(97)00341-7
更新日期：1997-05-23 00:00:00
abstract：:Single neurons in culture express a heterogeneity of neurotransmitter receptor subtypes. The study of the effects of neurotransmitters on neuronal function is complicated by this heterogeneity. It would therefore be useful to be able to identify live neurons that express the receptors of interest and then use these ne...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(96)00436-2
更新日期：1996-08-26 00:00:00
abstract：:Microtubule-associated protein 1B (MAP1B) is expressed at high levels during development of the nervous system and is localized primarily in neurons while specific phosphorylated isoforms of MAP1B are localized exclusively in growing axons. The levels of MAP1B are down regulated in most regions of the adult CNS, but r...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(99)01148-8
更新日期：1999-03-27 00:00:00
abstract：:In a previous study, we demonstrated that cholera toxin-A subunit, as well as the whole toxin, selectively blocks opioid-induced prolongation of the Ca2+ component of the action potential duration (APD) in dorsal root ganglion (DRG) neurons, indicating mediation of this excitatory effect by Gs-linked opioid receptors....
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(90)90751-v
更新日期：1990-10-29 00:00:00
abstract：:We measured the release of neuropeptide Y (NPY) from hippocampal slices of rats at various times after limbic seizures induced by a subcutaneous injection of 12 mg/kg kainic acid (KA). Two days after KA, 100 mM KCl induced a 1.6 +/- 0.2-fold increase in NPY release compared to saline-injected rats (P < 0.05), while sp...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(94)90847-8
更新日期：1994-10-10 00:00:00
abstract：:To determine whether oculomotor internuclear neurons (INOs) establish unilateral or bilateral connections with the abducens nucleus (nVI), horseradish peroxidase (HRP) and either DAPI or Nuclear Yellow (NY) were injected into nVI and the oculomotor complex (nIII) examined for retrogradely labeled cells. Such injection...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(83)90464-x
更新日期：1983-02-28 00:00:00
abstract：:The modulation of serotonin (5-HT) release by opioid receptors in the hippocampus of the awake, unrestrained rat was evaluated by use of in vivo microdialysis. The hippocampus was perfused with Ringer's solution (2 microliters/min), and extracellular levels of 5-HT and its major metabolite, 5-hydroxyindoleacetic acid ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)90456-w
更新日期：1993-06-04 00:00:00
abstract：:The calcium channel antagonists omega-agatoxin IIIA (omega-Aga-IIIA) and omega-conotoxin GVIA (omega-CgTx) were radioiodinated and used to locate binding sites in the rat brain by receptor autoradiography. While patterns of regional binding to sagittal sections of rat brain were generally similar for the 2 toxins, not...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(92)91034-c
更新日期：1992-10-23 00:00:00
abstract：:The effects of Morris water maze training on brain metabolism and behavior were compared between aged (20-22 months) and young (2-4 months) Fischer 344 male rats. Each group had yoked controls, which swam the same amount of time as the trained rats but without the platform. This was followed after 9 days by quantitati...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(02)02545-3
更新日期：2002-06-07 00:00:00
abstract：:Neonatal hypoxia-ischemia (HI) has been extensively studied in a rat model characterized by unilateral brain damage (Rice-Vannucci Model). However, as well as in humans, each rat brain hemisphere is distinctly involved in cognitive functions, as for example retrieval of emotionally based memory, and neurochemical asym...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(03)02436-3
更新日期：2003-05-30 00:00:00
abstract：:A major function of the dopamine in the striatum is to control the activity of its efferent systems which contain primarily GABAergic neurons. Direct intracerebral injections of haloperidol into the corpus striatum impaired the performance of rats trained to depress a lever in a sensitive reaction time task. Rats were...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(89)90186-8
更新日期：1989-04-03 00:00:00
abstract：:In order to investigate the interplay between visuo-spatial attention and central attention, we varied the relative probability (25% vs. 75%) of the responses to lateralized targets in an attentional blink paradigm. When the first target was associated with a less probable response, we observed a larger attentional bl...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2007.09.004
更新日期：2007-12-14 00:00:00
