Abstract：
:Electrical activities of thin hippocampal sections of the guinea pig were studied in vitro during and after administration of black widow spider venom (BSV). In CA3 neurons, BSV induced spontaneous discharges which were suppressed by Co2+ or Mn2+. During BSV administration, trains of potential changes resembling excitatory postsynaptic potentials (EPSPs) were recorded intracellularly. The EPSP-like potentials were blocked by TTX. BSV seems to induce impulses in presynaptic fibers or terminals and thereby facilitates release of neurotransmitters.
journal_name
Brain Resjournal_title
Brain researchauthors
Yamamoto C,Matsui Hdoi
10.1016/0006-8993(82)90103-2subject
Has Abstractpub_date
1982-07-29 00:00:00pages
382-6issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(82)90103-2journal_volume
244pub_type
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