The effects of monocular visual deprivation: disuse or binocular interaction?

Abstract:

:Patches of transnueronal degeneration were produced in the lateral geniculate nucleus (LGN) by retinal laser burns and a tarsorrhaphy was performed in the contralateral eye of Macaca mulatta during infancy. The adverse effect of unilateral visual deprivation on geniculate cell growth was absent in those portions of deprived LGN laminae that were located opposite a degenerated patch. This finding supports the hypothesis that arrest of geniculate cell growth from unilateral visual deprivation is caused by abnormal binocular interaction. However, the concurrent findings of arrest of cell growth in the monocularly innervated LGN changes, since abnormal binocular interaction cannot take place in those parts of the LGN that receive input exclusively from one eye.

journal_name

Brain Res

journal_title

Brain research

authors

Von Noorden GK,Crawford ML,Middle-Ditch PR

doi

10.1016/0006-8993(76)90772-1

subject

Has Abstract

pub_date

1976-07-30 00:00:00

pages

277-85

issue

2

eissn

0006-8993

issn

1872-6240

pii

0006-8993(76)90772-1

journal_volume

111

pub_type

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