Abstract：
:Intracisternal administration of aluminum maltolate to rabbits produces a marked argyrophilic neurofibrillary degeneration (NFD) which is also immunoreactive for both phosphorylated and non-phosphorylated microtubule associated protein tau. Using tissue fixation in PBF, the monoclonal antibodies Tau-2 and AT8 stain the NFD. Dephosphorylation markedly reduces the positivity of AT8. Using PLP-fixed tissue, monoclonal antibody Tau-1 also immunostains aluminum-induced NFD.
journal_name
Brain Resjournal_title
Brain researchauthors
Savory J,Huang Y,Herman MM,Reyes MR,Wills MRdoi
10.1016/0006-8993(94)01297-usubject
Has Abstractpub_date
1995-01-16 00:00:00pages
325-9issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(94)01297-Ujournal_volume
669pub_type
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