Ipsiversive turning behaviour after discrete unilateral lesions of the dorsal mesencephalic reticular formation by kainic acid.

Abstract:

:Discrete axon-sparing lesions were placed unilaterally in the mesencephalon by the local injection of kainic acid. Unilateral lesions of the dorsal reticular formation just beneath the superior colliculus and lateral to the periacqueductal grey resulted in consistent ipsiversive apomorphine-induced circling. Only weak motor asymmetries were observed after unilateral lesions restricted to the superior colliculus or to the periacqueductal grey. The results indicate that the dorsal mesencephalic reticular formation plays an essential role as an output station for striatal postural functions.

journal_name

Brain Res

journal_title

Brain research

authors

Mulas A,Longoni R,Spina L,Del Fiacco M,Di Chiara G

doi

10.1016/0006-8993(81)90579-5

subject

Has Abstract

pub_date

1981-03-16 00:00:00

pages

468-72

issue

2

eissn

0006-8993

issn

1872-6240

pii

0006-8993(81)90579-5

journal_volume

208

pub_type

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