Abstract：
:As a means of probing the chemotransducer, impulse sequences from in vitro, superfused sinus nerve-carotid body preparations were analyzed for departures from randomness. Twelve of 17 spike trains showed interval histograms that did not differ significantly from exponential. Thus these sequences resembled a Poisson (random) process with respect to time-independence of probability of occurrence of an event. However, 5 spike trains departed significantly from the exponential distribution forcing rejection of the Poisson model in these cases. Furthermore, mean interval vs standard deviation analysis revealed a significant positive correlation among intervals. These data suggest that the carotid body impulse generator possesses an intrinsic regularity and that the Poisson model does not accurately describe the in vitro sinus nerve interspike interval sequence.
journal_name
Brain Resjournal_title
Brain researchauthors
Nolan WF,Donnelly DF,Smith EJ,Dutton REdoi
10.1016/0006-8993(84)90908-9subject
Has Abstractpub_date
1984-01-30 00:00:00pages
194-7issue
1eissn
0006-8993issn
1872-6240pii
0006-8993(84)90908-9journal_volume
292pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract：:(1) Visual, auditory and olfactory input were not necessary for the performance of the lordosis reflex by female rats. Since taste is not involved in this behavior, somatosensory input must be sufficient for triggering the lordosis reflex. (2) Surgical cutaneous denervation markedly reduced the frequency and strength ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(76)90987-2
更新日期：1976-01-09 00:00:00
abstract：:To elucidate the intracellular mechanism of seizure discharge, phosphorylation of cellular protein during pentylenetetrazole (PTZ)-induced bursting activity in snail neurons was investigated. PTZ markedly enhanced the phosphorylation of proteins of 34,000 and 50,000 molecular weight. Similar effects were observed by a...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(86)91395-8
更新日期：1986-01-01 00:00:00
abstract：:Estrogen effects on tyrosine hydroxylase (TH), monoamine oxidase types A and B (MAO), and dopamine (DA) in microdissected regions of the hypothalamus, preoptic area and substantia nigra (SNR) of the female rat brain were investigated. Ovariectomized (OVX) young adult female rats were implanted with single silastic cap...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(90)90730-y
更新日期：1990-02-26 00:00:00
abstract：:Sprague-Dawley dams were treated with 3 v/v % ethanol in liquid diet from the 8th day gestation through 3 weeks nursing period. Offsprings, ages 1, 2 and 3 weeks, and their dams were studied. Brain weights and their total proteins were not affected by this ethanol treatment. Total enolase activity/mg protein and its i...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(92)90963-a
更新日期：1992-05-15 00:00:00
abstract：:The hippocampal formation of the rat contains two types of membrane-bound cholinergic binding sites, as revealed by specific binding of [3H]quinuclidinyl benzilate (QNB) or of a-[125I]bungarotoxin (a-Btx). The sites differ in pharmacological profile, sensitivity to detergents and ontogenesis. The major binding site (a...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(79)90211-7
更新日期：1979-04-27 00:00:00
abstract：:High levels of neurotensin/neuromedin N precursor mRNA, but few if any NT-positive perikarya have been detected in the dorsal subiculum of the adult rat or human hippocampus. This apparent discrepancy was tentatively ascribed to a lack of precursor mRNA translation or to a poor precursor posttranslational processing i...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(95)01083-3
更新日期：1995-12-08 00:00:00
abstract：:Accumulating evidence suggests that the neuropeptide substance P (SP) and its principal receptor neurokinin 1 (NK1) play a specific role in the behavioral response to opioids and stress that may help to initiate and maintain addictive behavior. In animal models, the NK1 receptor is required for opioids to produce thei...
journal_title：Brain research
pub_type： 杂志文章,评审
doi：10.1016/j.brainres.2009.11.014
更新日期：2010-02-16 00:00:00
abstract：:It has recently been shown that the immunosuppressant cyclosporin A (CsA) dramatically ameliorates the selective neuronal necrosis which results from 10 min of forebrain ischemia in rats. Since CsA is a virtually specific blocker of the mitochondrial permeability transition (MPT) pore which is assembled under adverse ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(97)00005-x
更新日期：1997-04-04 00:00:00
abstract：:The distribution of 125I-melatonin binding sites in 6 discrete brain regions of female rats at the estrous stage and the effects of ovariectomy and subsequent 17 beta-estradiol treatment on these binding sites were studied. Specific binding of 125I-melatonin was found in the hypothalamus, medulla-pons, hippocampus, ce...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(87)91057-2
更新日期：1987-01-27 00:00:00
abstract：:Mounting evidence suggests that sleep loss negatively affects learning and memory processes through disruption of hippocampal function. In the present study, we examined whether sleep loss alters the generation, differentiation, and survival of new cells in the dentate gyrus. Rats were sleep restricted by keeping them...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2005.10.020
更新日期：2005-12-14 00:00:00
abstract：:In the present study, uptake of glutamine by rat cerebellar granule cells, a predominantly glutamatergic nerve cell population, has been investigated. Glutamine is taken up by granule cells via at least three transport systems, A, ASC and L. The L-type low affinity system (K(m) = 2.6 mM) is the major transport system ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(97)00139-x
更新日期：1997-05-16 00:00:00
abstract：:The neurotoxic effects produced by ibotenic acid (IA) induced chemical lesions of the central nervous system (CNS) cholinergic system were examined on the opioid peptidergic system in adult rats. Forebrain cholinergic systems were bilaterally lesioned by the infusion of IA (1 or 5 micrograms/site) into the nucleus bas...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(92)90668-y
更新日期：1992-02-07 00:00:00
abstract：:It has been shown that 2-deoxy-D-glucose (2-DG) inhibits glucose utilization and elicits feeding through the lateral hypothalamus. In contrast, 2,5-anhydro-D-mannitol (2,5-AM), blocking glycogenolysis and/or gluconeogenesis, elicits feeding through the ventromedial hypothalamus. The aim of the present study was to det...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(96)00138-2
更新日期：1996-05-06 00:00:00
abstract：:Calcitonin gene-related peptide (CGRP) and substance P (SP) immunoreactivity was examined in neurons of the monkey trigeminal ganglion. Moreover, CGRP- and SP-positive varicose nerve fibers were found, occasionally forming pericellular arborizations around trigeminal somata, which, at light microscopic level, suggeste...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)91337-r
更新日期：1993-12-03 00:00:00
abstract：:The respiratory function of cerebral mitochondria harvested from genetically diabetic (BB/W) and streptozotocin-diabetic rats deprived of insulin for 3-4 weeks was found to be unchanged from control values. Furthermore, insulin-deprived BB/W rats subjected to 30 min of insulin-induced hypoglycemic coma demonstrated a ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(89)91624-7
更新日期：1989-02-13 00:00:00
abstract：:Metabolic dysfunction in the relay nuclei of the rat vibrissa circuit follows traumatic brain injury (TBI). This study examined the effects of mild (1.4-1.5 atm) parasagittal fluid-percussion injury on the electrophysiology of this circuit. TBI caused significant reductions in slope and increases in latency of vibriss...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(01)02424-6
更新日期：2001-06-15 00:00:00
abstract：:Computer-assisted morphometrics were used to characterize mature somatodendritic architecture in Golgi-stained neurons of the entopeduncular nucleus (EN) of the adult cat. Only one form of adult EN neuron was apparent and characterized by common features including: relatively large conical somata, long aspiny and mode...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(86)90766-3
更新日期：1986-06-11 00:00:00
abstract：:Rats anticipate a scheduled daily meal by entrainment of a circadian pacemaker separate from the light-entrainable circadian pacemaker located in the suprachiasmatic nuclei (SCN). The site and molecular mechanisms of the food-entrainable pacemaker are unknown. The intrinsic period (tau) of the SCN pacemaker is signifi...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(01)03042-6
更新日期：2001-11-23 00:00:00
abstract：:In the present research the role of gender in MDMA-induced hyperthermia and serotonin depletion is studied by injecting male and female male rats with MDMA or saline 3 times (i.p.) with 3h interval at dosages of 0.3, 1, 3 or 9 mg/kg at an ambient temperature of 25°C. The acute hyperthermia following the higher dosages...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2011.04.039
更新日期：2011-06-29 00:00:00
abstract：:Pretreatment with the alpha(2)-adrenoceptor agonist clonidine (31.25, 62.5, or 125 microg/kg, i.p.) dose-dependently reduced long-term potentiation (LTP) elicited in vivo in the occipital cortex of anesthetized rats, whereas pretreatment with the alpha(2)-adrenoceptor antagonist yohimbine (0.133, 0.4, or 1.2 mg/kg, i....
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2004.07.020
更新日期：2004-09-24 00:00:00
abstract：:We tested the hypothesis that intravenous infusion of human marrow stromal cells (hMSC) with a nitric oxide donor, (Z)-1-[N-(2-aminoethyl)-N-(2-ammonioethyl) aminio] diazen-1-ium-1,2-diolate (DETA/NONOate), enhances angiogenesis, neurogenesis and neurological functional recovery after stroke in rats compared to indivi...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2003.11.080
更新日期：2004-04-16 00:00:00
abstract：:The possible interference of nitric oxide (NO) in glucose metabolism was studied in activated astrocytes. Lipopolysaccharide (LPS) treatment triggered a NO-mediated increase in glucose consumption and lactate production, suggesting an enhanced rate of glycolysis. Active glycogen synthesis was also observed after LPS t...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(02)02877-9
更新日期：2002-07-26 00:00:00
abstract：:The effects of 3 different non-noxious stressors on body temperature (Tb) were investigated in the rat: (1) loose restraint in cylinders, (2) removal of the rats from cylinders, exposure to a novel environment and replacement in cylinders, a stressor called here 'novelty', and (3) gentle holding of the rats by the nap...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(84)90537-7
更新日期：1984-04-09 00:00:00
abstract：:The effect of neuroprotective drugs on the early and late electrophysiological manifestations of photothrombotic occlusion of distal branches of middle cerebral artery was studied in rats treated with MK-801 and Cerebrolysin (CL). DC potentials were recorded from the irradiated cortex (ischemic core), from the adjacen...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(97)01448-0
更新日期：1998-03-09 00:00:00
abstract：:In a previous study, we have demonstrated that an ovalbumin-like antigen is present within approximately one-half of all neurons of chicken spinal ganglia. The current study demonstrates this antigen co-localizes absolutely with neural intermediate filament protein (Peripherin) in small to medium-sized neurons of spin...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)90342-k
更新日期：1993-11-12 00:00:00
abstract：:Morphologic and metabolic aspects of androgen effects on the developing spinal cord were studied in organotypic cultures of the E13 (embryonic day 13) fetal mouse lumbosacral spinal cord, maintained as either hemisected, homologous explant pairs co-cultured with bulbocavernosus muscle (morphologic studies), or as whol...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(87)90769-4
更新日期：1987-03-17 00:00:00
abstract：:While genetic predisposition is a major factor, it is not known how development of attention-deficit/hyperactivity disorder (ADHD) is modulated by early life stress. The spontaneously hypertensive rat (SHR) displays the behavioral characteristics of ADHD (poorly sustained attention, impulsivity, hyperactivity) and is ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2015.11.019
更新日期：2016-06-15 00:00:00
abstract：:Norepinephrine (NE), acting on brain adrenoceptors, plays an important role in barrel field neuronal activity and plasticity. For this reason, the distribution of alpha 1- and alpha 2-adrenoceptors in the somatosensory cortex barrel field was studied by autoradiographic techniques in rats undergoing plastic change or ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)90005-8
更新日期：1993-09-24 00:00:00
abstract：:The bioelectric activity of the rat superior cervical ganglion (SCG) infected with pseudorabies virus (PRV) was examined in vitro 30-38 h after inoculation. Simultaneous intra- and extracellular recordings on the internal (ICN) and external carotid nerves (ECN) revealed a synchronized spontaneous activity. This synchr...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(82)90642-4
更新日期：1982-05-20 00:00:00
abstract：:Surgical microscopy and electrophysiological techniques were used to standardize the nomenclature for the pudendal nerve and sacral plexus according to their somatic axonal composition in the male rat. We conclude that the pudendal nerve is the segment running from the L6-S1 trunk to the sacral plexus, carrying effere...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(97)00408-3
更新日期：1997-07-25 00:00:00
