Abstract：
:The possible interference of nitric oxide (NO) in glucose metabolism was studied in activated astrocytes. Lipopolysaccharide (LPS) treatment triggered a NO-mediated increase in glucose consumption and lactate production, suggesting an enhanced rate of glycolysis. Active glycogen synthesis was also observed after LPS treatment, but NO synthase inhibition was unable to prevent this effect. These results strongly suggest that endogenously-formed NO stimulates glycolysis through a glycogenolysis-independent mechanism in astrocytes.
journal_name
Brain Resjournal_title
Brain researchauthors
Almeida A,Cidad P,Bolaños JPdoi
10.1016/s0006-8993(02)02877-9subject
Has Abstractpub_date
2002-07-26 00:00:00pages
131-4issue
1eissn
0006-8993issn
1872-6240pii
S0006899302028779journal_volume
945pub_type
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