Abstract：
:The regional hemodynamic basis of the cardiovascular response to acute noise stress in spontaneously hypertensive (SHR) and Wistar-Kyoto (WKY) rats and the role of the central amygdaloid nucleus in mediating this response was investigated. Using the pulsed Doppler flow probe technique it was determined that in response to noise, SHR exhibit a significantly greater percent increase in renal and mesenteric vascular resistance than WKY. Vascular responses in the hindquarter were similar in both groups. Bilateral lesion of the central amygdaloid nucleus or its output pathways to the brainstem decreased the cardiovascular response to noise in both SHR and WKY, with SHR and WKY lesion rats responding similarly. The central amygdaloid nucleus appears to participate in the cardiovascular response to acute noise stress in SHR and WKY. Although other structures in the limbic system network may contribute to integration of responses that involve the amygdala the present data suggest that this structure may play a central role in mediating the exaggerated cardiovascular responsiveness of SHR to environmental stress.
journal_name
Brain Resjournal_title
Brain researchauthors
Galeno TM,Van Hoesen GW,Brody MJdoi
10.1016/0006-8993(84)91257-5subject
Has Abstractpub_date
1984-01-23 00:00:00pages
249-59issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(84)91257-5journal_volume
291pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract：:The Wistar Audiogenic Rat (WAR) is a genetic model of reflex epilepsy with seizures induced by high-intensity sound stimulation (120 dB SPL). In spite of the known neural substrates involved in WAR seizure phenotype, neuroendocrine hypothalamic neurons were never investigated. In this work, AVP immunohistochemistry in...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2004.12.030
更新日期：2005-03-15 00:00:00
abstract：:Recently, the kinetics of fast axonal transport of a single type of organelle, the serotonergic storage vesicle, was described in an identified axon of Aplysia using a pulsing technique combined with intracellular injection of [3H]serotonin. Here we extended the single axon studies by analyzing the movement of pulses ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(81)91006-4
更新日期：1981-12-21 00:00:00
abstract：:The motoneurons innervating the orbicularis oculi muscle from a subgroup within the facial nucleus, called the intermediate facial subnucleus. This makes it possible to study afferents to these motoneurons by means of autoradiographical tracing techniques. Many different injections were made in the brainstem and dienc...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(86)90425-7
更新日期：1986-05-28 00:00:00
abstract：:Phenotypic diversity is shaped by both genetic and epigenetic mechanisms that program tissue specific patterns of gene expression. Cells, including neurons, undergo massive epigenetic reprogramming during development through modifications to chromatin structure, and by covalent modifications of the DNA through methyla...
journal_title：Brain research
pub_type： 杂志文章,评审
doi：10.1016/j.brainres.2008.07.074
更新日期：2008-10-27 00:00:00
abstract：:Rats with electrodes in either the posterior medial forebrain bundle (MFB), the anterior MFB, the medial prefrontal cortex, or the locus coeruleus self-stimulated during a 45 min period following the injection of [14C]2-deoxyglucose. They were then sacrificed and their brains prepared for autoradiography. The autoradi...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(83)91307-0
更新日期：1983-04-25 00:00:00
abstract：:Ischemic-reperfusion injury in humans occurs in conditions such as stroke, cardiac arrest, subarachnoid hemorrhage or head trauma. Maximal tissue damage is observed during reperfusion, which is primarily attributed to oxidative injury resulting from production of oxygen free radicals. One of the major consequences of ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(96)00009-1
更新日期：1996-04-22 00:00:00
abstract：UNLABELLED:This study examines the effects of progesterone on blood-brain barrier (BBB) integrity following thrombin administration. Thrombin is expressed in many diseases which affect neural tissue and is associated with breakdown of the BBB. Progesterone has shown protective effects on the BBB in stroke and traumatic...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2015.04.002
更新日期：2015-07-10 00:00:00
abstract：:We observed temporal changes in NACP (precursor protein of non-Abeta component of Alzheimer's disease amyloid), a presynaptic protein a.k. a. alpha-synuclein, in the hippocampus after 5 min ischemia. Intense NACP immunoreactivity was seen transiently around cerebral blood vessels in the CA1 subfield on day 4, and NACP...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(98)00033-x
更新日期：1998-03-30 00:00:00
abstract：:Chronic hydrocephalus is one of the severe complications after subarachnoid hemorrhage (SAH). However, there is no efficient treatment for the prevention of chronic hydrocephalus, partially due to poor understanding of underlying pathogenesis, subarachnoid fibrosis. Transforming growth factor-β1(TGF-β1) is a potent fi...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2015.11.004
更新日期：2016-01-01 00:00:00
abstract：:The mechanisms controlling the reorganisation of synaptic inputs to developing skeletal muscle fibres was studied using electrophysiological and histological methods. In the developing rat soleus muscle there is a rapid reduction of polyneuronal innervation between 9 and 12 days. Reducing the local concentration of ca...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0165-3806(86)90069-6
更新日期：1986-07-01 00:00:00
abstract：:Several investigations have shown that the N-methyl-D-aspartate (NMDA) antagonist MK-801 interferes both with learning and a candidate neural mechanism for learning, the long-term potentiation (LTP) phenomenon. The low doses of MK-801 reported to block learning, however, may not be sufficient to block LTP. The present...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(92)90371-f
更新日期：1992-01-08 00:00:00
abstract：:After-effects of fusimotor action on dynamic sensitivity of spindle primary afferents from soleus resulted from low rate stimulation of both static and dynamic gamma-axons. Sensitivity to small sinusoidal stretches superimposed on triangles was enhanced during triangular lengthening but not during shortening. These af...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(82)90289-x
更新日期：1982-01-28 00:00:00
abstract：:Chicks of 1-8 days after hatching were submitted to unilateral visual deprivation and, in both optic lobes, muscarinic receptors, labeled with L-[3H]quinuclidinyl benzylate [( 3H]L-QNB) and acetylcholinesterase (AChE) were assayed. Between 1 and 6 days the number of [3H]L-QNB binding sites was lower in the contralater...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0165-3806(84)90313-4
更新日期：1984-06-01 00:00:00
abstract：:NMDA receptor (NMDAR) antagonists such as ketamine, can reproduce many of the symptoms of schizophrenia. A reliable indicator of NMDAR channel blocker action in vivo is the augmentation of neuronal oscillation power. Since the coordinated and rhythmic activation of neuronal assemblies (oscillations) is necessary for p...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2019.146571
更新日期：2020-01-15 00:00:00
abstract：:The objective of this study was to assess the influence of Ca2+ influx on intracellular pH (pHi) of neocortical neurons in primary culture. Neurons were exposed to glutamate (100-500 microM) or KCl (50 mM), and pHi was recorded with microspectrofluorometric techniques. Additional experiments were carried out in which ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(95)00056-v
更新日期：1995-04-10 00:00:00
abstract：:We investigated the effects of neonatal optic nerve transection on cortical acetylcholinesterase (AChE) activity in hooded rats during postnatal development and following behavioral manipulation after weaning. AChE reaction product was quantified on digitized images of histochemically stained sections in layer IV of p...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2006.12.080
更新日期：2007-03-30 00:00:00
abstract：:Environmental stressors can substantially affect the adaptive response of rats to novelty in a sexually dimorphic manner. Gender-related differences are also observed in neurochemical and behavioural patterns of adult rats following prenatal exposure to diazepam (DZ). In the present study the behavioural reactivity to...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(01)02462-3
更新日期：2001-06-22 00:00:00
abstract：:We examined the effect of CP-154,526 on cardiovascular changes elicited in conscious rabbits by stressful stimuli (loud sound, cage move, pinprick, formaldehyde vapour and air-jet stress). CP-154,526 substantially reduced pressor and heart rate responses to these stimuli (both vagally and sympathetically mediated), an...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2004.05.062
更新日期：2004-08-13 00:00:00
abstract：:Conflicting results concerning the issue of whether or not chronic morphine exposure induces an increase in CCK biosynthesis have been found in many CNS sites, including the spinal cord, where CCK activity may contribute to the facilitation of the development of opiate tolerance. The present study was undertaken in or...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(99)01068-9
更新日期：1999-03-06 00:00:00
abstract：:Stimuli such as noise or hypoxia can induce a release of ATP into the cochlear fluid spaces. At nanomolar concentrations, ATP affects neurotransmission and electrochemical regulation of sound transduction. At higher concentrations, ATP may exert cytotoxicity acting on specific P2X(7) receptor subunits, thus contributi...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2006.05.094
更新日期：2006-08-09 00:00:00
abstract：:Spinal muscular atrophy is caused by deletions or mutations in the SMN1 gene that result in reduced expression of the SMN protein. The SMN protein is an essential molecular chaperone that is required for the biogenesis of multiple ribonucleoprotein (RNP) complexes including spliceosomal small nuclear RNPs (snRNPs). Re...
journal_title：Brain research
pub_type： 杂志文章,评审
doi：10.1016/j.brainres.2018.02.022
更新日期：2018-08-15 00:00:00
abstract：:Little is known about the association between brain white matter (WM) structure and motor function in humans. This study investigated complexity of brain WM interior shape as determined by magnetic resonance imaging (MRI) and its relationship with upper-extremity (UE) motor function in patients post stroke. We hypothe...
journal_title：Brain research
pub_type： 杂志文章,多中心研究
doi：10.1016/j.brainres.2008.06.008
更新日期：2008-09-04 00:00:00
abstract：:The acquisition and retention of tolerance to the antinociceptive effect of supraspinal morphine on the tail withdrawal reflex was assessed in rats implanted with unilateral cannulae in the periaqueductal gray (PAG). Development of tolerance to daily microinjections of morphine was indicated by the return of the tail ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(87)91476-4
更新日期：1987-10-27 00:00:00
abstract：:Rd mutant mice are visually blind but they maintain the ability of synchronising their circadian rhythms to the external light-dark cycles. We used immunocytochemical procedures to detect light-induced Fos expression in the rd mice retina. We found that Fos is expressed in the rd retina in an unattenuated pattern thro...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(99)01604-2
更新日期：1999-07-10 00:00:00
abstract：:Although Rolling mouse Nagoya (RMN) has been considered to demonstrate cerebellar dysfunction, our previous metabolic and electrophysiological studies also revealed a dysfunction of the basal ganglia, with the presumable primary site of dysfunction being the striatum. In the present study, we investigated the neuroche...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(95)01577-9
更新日期：1996-04-01 00:00:00
abstract：:The effects of adaptation/stimulus temperature (25 degrees C vs. 35 degrees C) on taste nerve responses to salt stimulation and amiloride suppression were assessed in rats. We measured the integrated responses of the chorda tympani nerve to 500 mM concentrations of NaCl, Na2SO4, sodium acetate (NaAc), KCl, K2SO4, pota...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/S0006-8993(96)01118-3
更新日期：1997-01-09 00:00:00
abstract：:During aerobic incubation at 37 degrees C, active uptake of labeled non-metabolizable alpha-aminoisobutyric acid (AIB) into isolated nodose ganglia (NG) excised from adult rats was accelerated to nearly twice that of the control, by the addition of glia maturation factor (GMF, 5 micrograms/ml) in a dose-dependent mann...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(86)90350-1
更新日期：1986-05-14 00:00:00
abstract：:The discovery of glucagon biosynthesis and receptors within mammalian brain has led one to suspect a neurotransmitter role for glucagon. In order to address this hypothesis in birds, we investigated the existence of glucagon receptors in duck brain by radioligand binding on fresh tissue sections and radioautography. S...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(94)90469-3
更新日期：1994-11-07 00:00:00
abstract：:Different groups of rats received three injections of either D-amphetamine (2.5 micrograms/0.5 microliters/side) or saline into the ventral tegmental area (VTA), one injection every third day. Two weeks following the last injection, dopamine (DA) neurotransmission in the nucleus accumbens (N. Acc.) was assessed with i...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)91761-g
更新日期：1993-03-12 00:00:00
abstract：:Routine cell stains disclose abnormal, usually single, nests of ectopic neurons in neocortical layer I of New Zealand Black (NZB) and BXSB autoimmune mice. We have suggested that these anomalies represent only the most visible part of more widespread cortical disorganization. In an attempt to determine the true magnit...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(90)90828-y
更新日期：1990-10-08 00:00:00
