NMDA receptor antagonist blocks the bradycardic but not the pressor response to L-glutamate microinjected into the nucleus tractus solitarius (NTS) of unanesthetized rats.

abstract：:Following acute intracerebroventricular injections of 1 ng of apamin and chronic apamin infusion (0.4 ng/microl, 0.5 microl/h, 14 days), the rat brains exhibited bilateral damage only in the cerebellum. The argyrophilic cells were Purkinje cells in copula pyramis, flocculus, paraflocculus, and paramedian lobules. Thes...

journal_title：Brain research

authors： Mourre C,Fournier C,Soumireu-Mourat B

更新日期：1997-12-19 00:00:00

abstract：:The innervation of the tensor tympani muscle of the middle ear in Macaca fascicularis (cynomolgus monkey) was studied using the horseradish peroxidase (HRP) neural tracing technique. A compact column of small trigeminal motoneurons was labeled ipsilaterally following intramuscular application of HRP to the tensor tymp...

journal_title：Brain research

authors： Gannon PJ,Eden AR

更新日期：1987-02-24 00:00:00

abstract：:Putative serotonergic dorsal raphe (DRN) neurons display a dramatic state-related change in behaviour, discharging regularly at a high rate during waking and at progressively slower rates during slow-wave sleep (SWS) and ceasing firing during paradoxical sleep (PS). Using the antidromic latency technique and extracell...

journal_title：Brain research

authors： Sakai K,Crochet S

更新日期：2001-04-20 00:00:00

abstract：:During the re-entrainment of the rat pineal N-acetyltransferase (NAT) rhythm to an 8-h advance of a light-dark (LD) cycle accomplished by shortening of one dark period, the advanced light period phase-delayed the evening NAT rise and phase-advanced the morning decline. The phase-relationship between the rise and the d...

journal_title：Brain research

authors： Illnerová H

更新日期：1989-08-14 00:00:00

abstract：:Extracellular action potentials were recorded from 691 neurons in the ventromedial hypothalamus (VMH) of urethane anesthetized female rats under acute and chronic sham-operated and hyperprolactinemic conditions. Hyperprolactinemia was produced by transplanting pituitaries under the kidney capsules. Neuronal excitabili...

journal_title：Brain research

authors： Moss RL,Chan A,Dudley CA

更新日期：1985-11-04 00:00:00

abstract：:Poor sleep and insomnia have been recognized to be strongly correlated with the development of depression. The exploration of the basic mechanism of sleep disturbance could provide the basis for improved understanding and treatment of insomnia and prevention of depression. In this study, 31 subjects with insomnia symp...

journal_title：Brain research

authors： Liu CH,Liu CZ,Zhang J,Yuan Z,Tang LR,Tie CL,Fan J,Liu QQ

更新日期：2016-10-01 00:00:00

abstract：:The purpose of this study was to determine the effects of specific proinflammatory cytokines interleukin-6 (Il-6), interleukin-1beta (Il-1beta), interferon-gamma (IFN), and tumor necrosis factor-alpha (TNFalpha), on content and distribution of alpha-synuclein (alpha-synuclein), tau and ubiquitin in human derived cultu...

journal_title：Brain research

authors： Bick RJ,Poindexter BJ,Kott MM,Liang YA,Dinh K,Kaur B,Bick DL,Doursout MF,Schiess MC

更新日期：2008-06-27 00:00:00

abstract：:The response of trunk neural crest cells taken from precise levels of the neural axis and cultured together with adjacent somites to Brain-derived neurotrophic factor (BDNF), was examined in cultures grown in a chemically defined medium. In control cultures, the number of neural crest-derived neurons expressing the HN...

journal_title：Brain research

authors： Kalcheim C,Gendreau M

更新日期：1988-06-01 00:00:00

abstract：:Inoculation of the tail base of rats with Mycobacterium butyricum led to an arthritic swelling and inflammation of the limbs which displayed a hyperalgesia to noxious pressure: these effects peaked at 3 weeks postinoculation. In vitro autoradiography of coronal sections of rat brain was used for a parallel determinati...

journal_title：Brain research

authors： Millan MJ,Morris BJ,Colpaert FC,Herz A

更新日期：1987-07-28 00:00:00

abstract：:Previous studies resulted in conflicting conclusions that glutamate application either decreases or increases the activity of Ca2+ channels in hippocampal neurons. We studied whole-cell Ca2+ currents (ICa) in chick dorsal root ganglion neurons and rat hippocampal cells. For both cell types glutamate (1-30 microM) incr...

journal_title：Brain research

authors： Mironov SL,Lux HD

更新日期：1992-05-15 00:00:00

abstract：:The role of subcortical input and/or output pathways in the development of cortical networks was examined in organotypic tissue cultures derived from neonatal mouse brain. Comparisons were made between cultures of cerebral neocortex grown with large amounts of subcortical tissue and those that were completely isolated...

journal_title：Brain research

authors： Leiman AL,Seil FJ

更新日期：1986-02-19 00:00:00

abstract：:We assessed muscarinic M(1), M(2) and M(4) receptor subtypes in the hippocampus of Alzheimer's and control brains by receptor autoradiography using ligands such as [(125)I]muscarinic toxin-1 ([(125)I]MT-1, M(1) selective), [(3)H]AFDX-384 (M(2) partially selective) and [(125)I]muscarinic toxin 4 ([(125)I]M(4) toxin-1, ...

journal_title：Brain research

authors： Mulugeta E,Karlsson E,Islam A,Kalaria R,Mangat H,Winblad B,Adem A

更新日期：2003-01-17 00:00:00

abstract：:Several studies have recently shown that basal and stress-induced secretion of corticosterone may enhance vulnerability to drugs of abuse. In this report, we studied the effects of metyrapone, an inhibitor of the synthesis of corticosterone, on cocaine-induced locomotion and on the relapse of cocaine self-administrati...

journal_title：Brain research

authors： Piazza PV,Marinelli M,Jodogne C,Deroche V,Rougé-Pont F,Maccari S,Le Moal M,Simon H

更新日期：1994-09-26 00:00:00

abstract：:Methionine (Met) enkephalin is detectable in rat hypothalamic and neurointermediate lobe (NIL) tissue extracts using a specific radioimmunoassay. Reversed-phase HPLC revealed that only the pentapeptide form was present in the extracts. Total amounts of Met-enkephalin in extracts containing the median eminence (ME), su...

journal_title：Brain research

authors： Jessop D,Sidhu R,Lightman SL

更新日期：1990-05-14 00:00:00

abstract：:This paper reports studies on the biotransformation of the nonapeptide arginine-vasotocin (AVT) by both rat and chicken brain synaptic membranes. The fragments which were formed during digestion of AVT1-9, were isolated by high pressure liquid chromatography (HPLC) and chemically characterized by amino acid compositio...

journal_title：Brain research

authors： Wang XC,Burbach JP,Verhoef JC,De Wied D

更新日期：1983-09-19 00:00:00

abstract：:We tested the hypothesis that a single systemic injection of 380 mg/kg of the muscarinic agonist pilocarpine would produce more diffuse and severe seizure-induced brain damage than a single injection of lithium (3 mEq/kg) followed 4 h later by < 1/10 the dosage of pilocarpine. The hypothesis was not supported; the pat...

journal_title：Brain research

authors： Bureau YR,Peredery O,Persinger MA

更新日期：1994-06-20 00:00:00

abstract：:Several labeled neurotransmitter substances or precursors ( [3H]histamine, [3H]serotonin, and [3H]choline) were injected with pressure into the cell body of C2, an identified putative histaminergic neuron in the cerebral ganglion of Aplysia in order to study the selectivity of axonal transport. We examined transport o...

journal_title：Brain research

authors： Gotoh H,Schwartz JH

更新日期：1982-06-17 00:00:00

abstract：:Previous studies suggested the existence of two populations of cells in the mammalian sympathetic nervous system which differ in their ability to express phenylethanolamine N-methyltransferase (PNMT), the enzyme which specifically subserves the biosynthesis of epinephrine: (1) sympathoblasts and their progeny, the nor...

journal_title：Brain research

authors： Teitelman G,Skaper S,Baker H,Park DH,Joh TH,Adler R

更新日期：1984-04-01 00:00:00

abstract：:Glutamate stimulation of the lateral supramammillary nucleus (SUL) in urethane anaesthetized rats produced a substantial increase in the amplitude of the perforant path-evoked population spike in the dentate gyrus, without affecting the population EPSP slope. One third of the spike enhancements lasted longer than 20 m...

journal_title：Brain research

authors： Carre GP,Harley CW

更新日期：1991-12-24 00:00:00

abstract：:Alpha-synuclein is a natively unfolded protein playing a key role in the regulation of several neuronal synaptic functions in physiological and pathological conditions. Many studies, over the past years, have shown that it is actively involved in PD pathophysiology. Alpha-synuclein is integrated in a complex network o...

journal_title：Brain research

authors： Bellucci A,Zaltieri M,Navarria L,Grigoletto J,Missale C,Spano P

更新日期：2012-10-02 00:00:00

abstract：:The startle reflex is an unconditioned, quantifiable behavior used to study sensory modalities. We examined whether the acoustic startle reflex (ASR) was sensitive to lesions induced by focal cerebral ischemia. Sprague-Dawley rats were pre-screened for startle reflex responses 3-6 days prior to surgery and there were ...

journal_title：Brain research

authors： Maynard KI,Sukoff SJ,Ji Z,Wettstein JG,Black MD

更新日期：2005-01-25 00:00:00

abstract：:A histo-enzymatic technique for visualizing and quantifying endogenous NAD(H) in brain tissue was developed, based on coupled enzymatic cycling reactions that reduce nitrotetrazolium blue chloride to produce formazan. Conditions were used where the endogenous level of nicotinamide adenine dinucleotides (NAD(H)) was th...

journal_title：Brain research

authors： Balan IS,Fiskum G,Kristian T

更新日期：2010-02-26 00:00:00

abstract：:Studies of the subcellular localization of neuroreceptors in the rat brain have shown that most of them are associated with light and low density subcellular fractions. In two human brain areas, quite different subcellular distributions were observed. After fractionation by differential centrifugation of frontal corte...

journal_title：Brain research

authors： Maloteaux JM,Luabeya MK,Vanisberg MA,Jeanjean AP,Baudhuin P,Scherman D,Laduron PM

更新日期：1995-07-31 00:00:00

abstract：:The ability of crude cerebrum supernatant to stabilize, at a low temperature, cold-labile microtubules purified from beef brain was studied during development in the rat. The cold-stabilizing activity of the supernatant was low during the first postnatal week, rose significantly during the second postnatal week, and t...

journal_title：Brain research

authors： Faivre-Sarrailh C,Rabié A

更新日期：1988-08-01 00:00:00

abstract：:To characterize optical responses (ORs) evoked by white matter (WM) stimulation in slices of rat visual cortex (VC) stained with voltage sensitive dyes, time course of ORs in each layer was investigated by recording ORs with a linearly aligned photodiode array, and the spatial patterns of the ORs at specified time aft...

journal_title：Brain research

authors： Tanifuji M,Yamanaka A,Sunaba R,Terakawa S,Toyama K

更新日期：1996-10-28 00:00:00

abstract：:The excitatory amino acid L-glutamate injected into the nucleus of the solitary tract (NTS) in unanesthetized rats similar to peripheral chemoreceptor activation increases mean arterial pressure (MAP) and reduces heart rate. In this study, we investigated the effects of acute (1 day) and chronic (15 days) electrolytic...

journal_title：Brain research

authors： Vieira AA,Colombari E,De Luca LA Jr,de Almeida Colombari DS,Menani JV

更新日期：2004-10-29 00:00:00

abstract：:This study investigated the effects of the calcium channel blockers nicardipine, calcicludine, omega-conotoxin GVIA, omega-agatoxin IVA, SNX-482, and NiCl on spontaneous muscle action potential of a rat spinal cord-muscle co-culture system. Spontaneous muscle action potential of the innervated muscle cells was blocked...

journal_title：Brain research

authors： Taguchi K,Shiina M,Shibata K,Utsunomiya I,Miyatake T

更新日期：2005-02-09 00:00:00

abstract：:Electrical and pharmacological properties of currents induced by compounds having affinities for putative sigma receptors were investigated with NCB20 cells by use of the whole-cell patch-clamp technique. Antipsychotics and naloxone induced inward currents with a decrease in membrane conductance at a holding potential...

journal_title：Brain research

authors： Morio Y,Tanimoto H,Yakushiji T,Morimoto Y

更新日期：1994-02-21 00:00:00

abstract：:Cerebral blood flow (CBF) and blood flow (BF) in extracerebral head structures were measured during the sleep-wake cycle in rats using radioactive microspheres. While no statistically significant changes occurred in the transition from Waking to quiet sleep (also referred to as synchronized or non-REM Sleep), CBF incr...

journal_title：Brain research

authors： Zoccoli G,Bach V,Cianci T,Lenzi P,Franzini C

更新日期：1994-03-28 00:00:00

abstract：:In kittens, but not in adult cats, depriving one eye of pattern vision by suturing the lids shut (monocular deprivation or MD) for one week reduces the proportion of binocular units in the visual cortex. A sensitivity of cortical units in adult cats to MD can be produced by infusing exogenous monoamines into the visua...

journal_title：Brain research

authors： McCall MA,Tieman DG,Hirsch HV

更新日期：1982-11-04 00:00:00