Population spike facilitation in the dentate gyrus following glutamate to the lateral supramammillary nucleus.

Abstract:

:Glutamate stimulation of the lateral supramammillary nucleus (SUL) in urethane anaesthetized rats produced a substantial increase in the amplitude of the perforant path-evoked population spike in the dentate gyrus, without affecting the population EPSP slope. One third of the spike enhancements lasted longer than 20 min. These data suggest that SUL afferents provide a mechanism for both short- and long-lasting heterosynaptic modulation of hippocampal throughput.

journal_name

Brain Res

journal_title

Brain research

authors

Carre GP,Harley CW

doi

10.1016/0006-8993(91)91415-w

subject

Has Abstract

pub_date

1991-12-24 00:00:00

pages

307-10

issue

1-2

eissn

0006-8993

issn

1872-6240

pii

0006-8993(91)91415-W

journal_volume

568

pub_type

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