Abstract：
:Horseradish peroxidase was injected intracellularly into motoneurons responding to cutaneous stimulation of the central foot pad of the hind limb in cats. Three motoneurons were selected for detailed analysis: two excited by foot pad stimulation, and one postsynaptically inhibited by such stimulation. The overall lengths of the dendritic trees of the 3 cells ranged from 15.2 to 20.4 mm; the total surface areas ranged from 0.161 to 0.185 mm2. One cell had 9 primary dendrites, 39 terminal dendrites, and 69 dendritic branches in all. The second cell had 8 primary dendrites, 44 terminal dendrites, and 80 dendritic branches in all. For the third cell, these numbers were 14, 76 and 136. 75.2% of the total dendritic length of one of the cells was accounted for by branches of 3 of its 9 primary dendrites; for the second, 69.1% by 3 of 8; and for the third cell, 47.9% by 3 of 14. In contrast to the marked disparity in overall length of branches of the various primary dendrites, when the lengths of dendrites were analyzed by order of branching, dendritic branches of orders II-V each included greater than 15% of overall dendritic length. All 3 motoneurons displayed an exponential overall loss of total dendritic width with distance from the cell body, as well as an exponential decrease in Rall's dendritic trunk parameter. Four different patterns of branching were observed. Mean estimated electronic dendritic lengths were 1.3 for two cells, and 1.2 for the third. However, 13% to 28% of the dendrites of the 3 cells terminated more than two space constants from the cell body. In spite of striking differences among these cells in first-order morphology, on many of the detailed measures characterizing the dendritic trees of these motoneurons, they proved to be strikingly similar.
journal_name
Brain Resjournal_title
Brain researchauthors
Egger MD,Egger LDdoi
10.1016/0006-8993(82)90669-2subject
Has Abstractpub_date
1982-12-16 00:00:00pages
19-30issue
1-2eissn
0006-8993issn
1872-6240pii
0006-8993(82)90669-2journal_volume
253pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract：:Our previous studies indicated that L-type calcium channel blocker diltiazem could potentiate pentobarbital-induced hypnosis through serotonergic system. In view of the important role of dorsal raphe nucleus (DRN) on the sleep regulation and the pharmacological actions of calcium channel blocker, we presumed that Ca(2...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2011.05.064
更新日期：2011-07-27 00:00:00
abstract：:In Long-Evans Cinnamon (LEC) rats of three different ages (7, 13 and 32 weeks old) concentrations of Cu, Zn and Fe were measured in 8 regions of the brain. The LEC groups aged 7 and 13 weeks showed low concentrations of Cu in all regions compared to Long-Evans Agouti (LEA) rats. In 32-week-old LEC rats, however, Cu co...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(92)91587-5
更新日期：1992-08-21 00:00:00
abstract：:The development of afferent projections to the cerebellum was studied by making small (20 nl) injections of True blue into the cerebella of neonatal rats under general anaesthesia. Neurones in all main precerebellar nuclei were labelled even in rats less than one day old. With the exception of the disappearance of sma...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0165-3806(88)90037-5
更新日期：1988-04-01 00:00:00
abstract：:Despite significant advancements in the understanding of the pathophysiological mechanisms of subarachnoid hemorrhage (SAH), little is known about the emotional consequences. The primary goal of this study was to describe the locomotor and behavioral patterns in rats following both a single-injection and double-inject...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2012.10.061
更新日期：2013-01-23 00:00:00
abstract：:Several neurologic illnesses in which excitotoxic mechanisms may play a role increase in prevalence with age. In the present study we examined the susceptibility of rats to quinolinic acid striatal lesions at 1, 4 and 20 months of age, and susceptibility to N-methyl-D-aspartate (NMDA) at 1 and 4 months of age. The ext...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(91)90631-5
更新日期：1991-10-25 00:00:00
abstract：:The properties of [3H]dihydropyridine (DHP), nitrendipine and (+)-PN 200-110, binding to rat cerebral membranes were investigated. In normotensive Wistar-Kyoto (WKY) adult rats, the highest densities of [3H]DHP binding sites were found in the hippocampus. Frontal cerebral cortex and hypothalamus had intermediate level...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(87)91446-6
更新日期：1987-05-26 00:00:00
abstract：:A complete gap of 3-4 mm was surgically created in the spinal cord of adult rats between the T8-T10 vertebral level, filled with a collagen matrix and closed with sutures. Animals were killed at weekly intervals from 14 to 42 days postimplantation. The collagen implant (CI) was evaluated for ingrowth of blood vessels ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(90)90227-3
更新日期：1990-03-12 00:00:00
abstract：:Antibodies were raised in rabbits against the neuropeptide N-acetyl-L-aspartyl-L-glutamate (NAAG) coupled to bovine serum albumin via a carbodiimide linkage. One of these rabbit antisera, which preferentially recognizes coupled NAAG-like immunoreactivity (LIR), has been previously used to immunocytochemically localize...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0169-328x(88)90045-9
更新日期：1988-06-01 00:00:00
abstract：:Monoclonal antibody N210 (mabN210) recognizes the 210 kdalton neurofilament protein in mammals and gives characteristic immunocytochemical staining of neurofilament-rich processes. For example, in the cerebellum it recognizes myelinated axons and the calyx formed by basket cell axon collaterals. The distribution of ma...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(86)90937-6
更新日期：1986-07-23 00:00:00
abstract：:Commissural and ipsilateral intrinsic connections of the vestibular nuclear complex of cats were investigated using retrograde transport of horseradish peroxidase (HRP). HRP was microiontophoretically injected into limited areas (0.2-0.5 mm in diameter) of the respective vestibular nuclei. In the commissural connectio...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(85)91474-x
更新日期：1985-08-19 00:00:00
abstract：:The aim of this study was to assess the effect of Alzheimer's disease has on the functional integrity of several signal transduction proteins. The relative levels of the G-protein alpha subunits Gs alpha-L, Gs alpha-S, Gi alpha-2 and G(o) alpha were measured by western blotting and found to be unchanged in membranes p...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)90798-r
更新日期：1993-09-17 00:00:00
abstract：:The nitric oxide (NO) metabolome and the NO metabolite-based neurovascular protective pathways are dysregulated after stroke. The major NO metabolite S-nitrosoglutahione (GSNO) is essential for S-nitrosylation-based signaling events and the inhibition of S-nitrosoglutahione (GSNO)-metabolizing enzyme GSNO reductase (G...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2020.146879
更新日期：2020-08-15 00:00:00
abstract：:We studied whether the antinociceptive effect produced by intracerebroventricular injection of delta-sleep-inducing peptide (DSIP) to mice involved the monoaminergic pathways that descended from brainstem to spinal cord (the descending inhibitory systems). In the tail-pinch test, the antinociceptive effect of DSIP was...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(89)91569-2
更新日期：1989-02-20 00:00:00
abstract：:An extensive exploration of the discriminating properties of olfactory receptors cells has been conducted in our laboratory through the statistical processing of single cell responses recorded in the frog's olfactory epithelium. Similarities between odorant stimulating properties could be demonstrated by comparing the...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(84)90764-9
更新日期：1984-02-06 00:00:00
abstract：:Event-related potentials (ERP) were measured when pleasant, neutral or unpleasant pictures were presented in the context of similarly valenced stimuli, and compared to ERPs elicited when the same pictures were viewed in an intermixed context. An early ERP component (150-300 ms) measured over occipital and fronto-centr...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2007.10.072
更新日期：2008-01-16 00:00:00
abstract：:We used triple-labeling immunohistochemistry in rat midbrain sections to identify dopaminergic neurons that contain either one or both of the calcium-binding proteins, calretinin (CR) and calbindin-D28k (CB). Midbrain dopaminergic neurons were immunohistochemically labeled for tyrosine hydroxylase (TH), CR, and CB. In...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(99)01950-2
更新日期：1999-10-30 00:00:00
abstract：:The present investigations were designed to assess the effect of the serotoninergic system on luteinizing hormone (LH) and LH-releasing hormone (LH-RH) secretion in female rats aged 14 and 30 days. The administration of 5-hydroxytryptophan (5-HTP; 75 mg/kg i.p.) increased hypothalamic serotonin (5-HT) concentrations i...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(90)91634-s
更新日期：1990-07-16 00:00:00
abstract：:The morphological basis of how visceral information from the nucleus of the solitary tract (NTS) is relayed from the parabrachial nucleus (PBN) to the central nucleus of the amygdala (Ce) was studied at the light and electron microscopic levels using the anterograde tracer, Phaseolus vulgaris leucoagglutinin (PHA-L), ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(94)91262-9
更新日期：1994-11-14 00:00:00
abstract：:The regulation of corticosteroid receptor expression in the rat brain by adrenal steroids remains controversial. The results of in vivo studies [Brinton and McEwen, 1988; Luttge et al., 1989] suggest that activation of type I receptors can modulate both mineralocorticoid (MR; type I) and glucocorticoid (GR; type II) r...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(94)90174-0
更新日期：1994-02-04 00:00:00
abstract：:Recent pharmacological and morphological studies have raised the likelihood of a regulatory link between the neuropeptide Y (NPY) and beta-endorphin (beta-END) networks in the hypothalamus. To evaluate this link we have examined the effects of NPY administration on the in vivo release of beta-END by push-pull perfusio...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(95)01284-2
更新日期：1995-12-24 00:00:00
abstract：:Early brain injury (EBI) plays a pivotal role in the prognosis of patients with subarachnoid haemorrhage (SAH). Dexmedetomidine (DEX), a highly selective α2 receptor agonist, is reported to exert multiple protective effects in many neurological diseases. This study was designed to investigate whether DEX had neuroprot...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2018.05.040
更新日期：2018-11-01 00:00:00
abstract：:Circular RNAs (circRNAs) are a class of covalently closed non-coding RNAs, and aberrant alteration of their expression patterns is studied in numerous diseases. This study aimed to investigate whether intracerebral hemorrhage (ICH) affected circRNA expression profiles in the rat brain. Adult male Sprague-Dawley rats w...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2019.146490
更新日期：2020-01-01 00:00:00
abstract：:In this research, we investigated striatal neurogenesis in 3-, 6-, 12-, and 18-month-old rats after cerebral ischemic injury. All rats were subjected to a 20-min middle cerebral artery occlusion (MCAO), given 5'-bromodeoxyuridine (BrdU, 30 mg/kg, i.p.) once daily during days 4-7 and sacrificed 2 weeks after MCAO. Neur...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2007.06.043
更新日期：2007-08-29 00:00:00
abstract：:Ion-selective microelectrode techniques were used to study extracellular K+ changes associated with penicillin-induced epileptogenesis in the CA3 region of hippocampal slices. Recordings were made in slices taken from rats 9-16 days of age, which have a pronounced capacity to undergo prolonged synchronized afterdischa...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(86)80203-7
更新日期：1986-12-01 00:00:00
abstract：:Qualitative and computer-assisted analyses were performed on Golgi-impregnated neurons which were serially reconstructed in 3 dimensions. Analysis of the temporal pattern of growth indicated that the initial outgrowth, formation of the adult number of dendrites and virtually all dendritic branching occurred in the pre...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0165-3806(86)90192-6
更新日期：1986-01-01 00:00:00
abstract：:We sought to characterize regional heterogeneity of astrocytes using adrenergic receptor sites as cellular markers. Primary cultures made from 6 regions of neonatal rat brain consisted almost exclusively of astrocytes. Membranes from astrocytes cultured 1-3 weeks were prepared for radioligand binding assays of beta- a...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(90)91027-e
更新日期：1990-05-28 00:00:00
abstract：:The 2009 influenza A(H1N1) pandemic led to a particularly high risk of morbidity and mortality among pregnant women. Therefore, inactivated influenza vaccines have been widely recommended for women in any period of gestation. Recent studies have shown that the peripheral adaptive immune system plays an important role ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2014.09.076
更新日期：2014-12-10 00:00:00
abstract：:Prolonged electrical stimulation of the perforant pathway in the rat evokes epileptiform discharges in dentate granule cells and irreversibly damages hilar neurons. In this in vivo study, we demonstrate that similar perforant path stimulation in C57Bl/6 mice causes the same pattern of hippocampal neuron loss. Therefor...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2006.02.055
更新日期：2006-04-26 00:00:00
abstract：:The mechanisms controlling the reorganisation of synaptic inputs to developing skeletal muscle fibres was studied using electrophysiological and histological methods. In the developing rat soleus muscle there is a rapid reduction of polyneuronal innervation between 9 and 12 days. Reducing the local concentration of ca...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0165-3806(86)90069-6
更新日期：1986-07-01 00:00:00
abstract：:Considerable disagreement exists concerning the degree to which sparing and/or recovery of function occurs following CNS damage at birth rather than in adulthood. To study this question, the spinal cord was hemisected in neonatal and adult cats and the motor behavior of the two groups was compared when the neonatal op...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0165-3806(83)90046-9
更新日期：1983-08-01 00:00:00
