Abstract:
:During the re-entrainment of the rat pineal N-acetyltransferase (NAT) rhythm to an 8-h advance of a light-dark (LD) cycle accomplished by shortening of one dark period, the advanced light period phase-delayed the evening NAT rise and phase-advanced the morning decline. The phase-relationship between the rise and the decline became so compressed that after the second and the third light period the NAT rhythm was not expressed even in constant darkness and reappeared only within another cycle at the time of the original night. Only after the fourth advanced light period, the NAT rhythm phase-jumped into the advanced night.
journal_name
Brain Resjournal_title
Brain researchauthors
Illnerová Hdoi
10.1016/0006-8993(89)90605-7subject
Has Abstractpub_date
1989-08-14 00:00:00pages
365-8issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(89)90605-7journal_volume
494pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract::Repeated administration of high doses of methamphetamine produced long-term decreases in dopamine (DA) levels and in the number of DA uptake sites in the rat striatum. These two effects were dose-related and did not appear to be due to the continued presence of drug in striatal tissue. Long-lasting depletions induced ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)91265-2
更新日期:1980-01-06 00:00:00
abstract::Insular cortex (INS) plays a critical role in pain processing and shows sex differences in functional activation during noxious visceral stimulation. Less is known regarding functional interactions within the INS and between this structure and other parts of the brain. Cerebral blood flow mapping was performed using [...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2019.04.005
更新日期:2019-08-15 00:00:00
abstract::Individual vulnerability to the reinforcing effects of drugs appear to be a crucial factor in the development of addiction in humans. In the rat, individuals at risk for psychostimulant self-administration (SA) may be identified from their locomotor reactivity to a stress situation such as exposure to a novel environm...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(91)91452-7
更新日期:1991-12-13 00:00:00
abstract::The effects of amphetamine were examined in a brain stimulation reward paradigm in which response rate was measured across a range of stimulation frequencies. Both low (0.0625 and 0.125 mg/kg) and high (1.0, 2.0 and 4.0 mg/kg) doses of systemic amphetamine decreased the stimulation frequency needed to sustain low rate...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(88)90653-1
更新日期:1988-09-06 00:00:00
abstract::The sites of action of lidocaine on the responses evoked by stimulation of lateral column (LC) and dorsal root (DR) were studied in the isolated, intra-arterially perfused spinal cord of the bullfrog. When the ventral root volley produced by stimulation was abolished by lidocaine, the presynaptic focal potential was a...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(82)90172-x
更新日期:1982-10-07 00:00:00
abstract::Melatonin is synthesized rhythmically under control of circadian oscillators by the retinas of non-mammalian vertebrates. Here we report that the retinas of some strains of laboratory mice exhibit robust circadian rhythms of melatonin synthesis which can be entrained by light in vitro. The rd mutation results in progr...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(97)01446-7
更新日期:1998-04-13 00:00:00
abstract::Chemokine receptors, and in particular CXCR4 and CCR5 play a key role in the neuropathogenesis of Human Immunodeficiency Virus-1 (HIV)4 associated dementia (HAD). Thus, new insight into the expression of CXCR4 in the central nervous system may help develop therapeutic compounds against HAD. Brain-derived neurotrophic ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2008.05.086
更新日期:2008-08-28 00:00:00
abstract::Cerebral venous thrombosis (CVT) is a rare form of cerebral stroke that causes a variety of symptoms, ranging from mild headache to severe morbidity or death in the more severe forms. The use of anti-coagulant or thrombolytic agents is the classical treatment for CVT. However, the development of new therapies for the ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2018.06.029
更新日期:2018-11-15 00:00:00
abstract::Dopamine-beta-hydroxylase (DBH), the enzyme that converts dopamine to norepinephrine, has been localized in light and electron microscopic preparations of rat brain by an immunocytochemical method using a peroxidase--anti-peroxidase Fab complex. In light microscopic preparations, DBH-specific reaction product was obse...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(79)90755-8
更新日期:1979-02-16 00:00:00
abstract::Hydrogen-rich water (HRW) has anti-oxidant activities, and it exerts neuroprotective effects during ischemia-reperfusion brain injury. Parvalbumin and hippocalcin are two calcium buffering proteins, which are involved in neuronal differentiation, maturation and apoptosis. The aim of this study was to investigate wheth...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2015.04.038
更新日期:2015-07-30 00:00:00
abstract::Transport of fragmented DNA in apical dendrites of the CA1 pyramidal neurons of gerbil hippocampus is observed in the apoptotic process following transient forebrain ischemia. The time-course of specific DNA fragmentation was examined after the ischemic insult by in situ nick-end-labeling method and fluorescence detec...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(98)00753-7
更新日期:1998-09-28 00:00:00
abstract::Serotonin (5HT) is thought to reset the biological clock in the suprachiasmatic nuclei (SCN) in vitro through a postsynaptic 5HT-1a receptor. Thus we examined 5HT receptor gene expression in the SCN by in situ hybridization. On film autoradiograms, 5HT-1c receptor mRNA showed intense SCN hybridization, while 5HT-1b re...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(93)90789-p
更新日期:1993-04-09 00:00:00
abstract::Brain cortico-striatal circuits have consistently been implicated in the pathology of addiction related disorders. We applied a reliable seed-based analysis of the resting-state brain activity to comprehensively delineate the subdivisions of striatal functional connectivity implicated in internet gaming disorder. Amon...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2014.12.042
更新日期:2015-03-30 00:00:00
abstract::The effect of intrathecal (i.t.) galanin (GAL) on the prolonged increase of spinal reflex excitability produced by conditioning stimulation (CS) of unmyelinated muscle afferents was studied in decerebrate, spinalized, unanesthetized rats. A CS train (1 Hz, 20 s) applied to the unmyelinated fibers in the gastrocnemius ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(91)91037-2
更新日期:1991-02-15 00:00:00
abstract::The presence of calretinin and calbindin immunoreactivity is studied in the retina of larval and adult lamprey and their respective distributions are compared. Calretinin distribution is also studied in the retina of transforming stages. Western blot analysis in brain extracts showed a 29-kDa band with both polyclonal...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2005.11.014
更新日期:2006-01-12 00:00:00
abstract::During aging, estrogen production and circulating levels of estrogen are markedly decreased in females. Although several differences exist in the process of reproductive aging between women and female rats, the results of many studies suggest that the female rat, especially the middle-aged or aged ovariectomized femal...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2013.11.010
更新日期:2014-01-16 00:00:00
abstract::A recent physiological report suggested that neurotensin could inhibit the vasopressin releasing from vasopressin-producing neurons in the hypothalamic paraventricular nucleus but not in the supraoptic nucleus. In the present study, the synaptic relationship between the neurotensin-like immunoreactive and vasopressin-...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(99)01455-9
更新日期:1999-07-10 00:00:00
abstract::In vitro quantitative autoradiography of high-affinity [3H]desmethylimipramine (DMI) binding sites was performed on 24 human brains postmortem. Highest densities of binding sites were found in portions of the amygdala, the granular layer of the dentate gyrus, the pyramidal layer of CA4. Next, in descending order were ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(88)90353-8
更新日期:1988-07-19 00:00:00
abstract::Kindling of the amygdaloid complex in rats results in an enhanced emotionality frequently expressed by an elevated anxiety and defensive attitude toward other animals. Defensive attitude may have important consequences in social context and if tested in a large space it may eventually lead to social withdrawal. To tes...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(01)03162-6
更新日期:2001-12-13 00:00:00
abstract::Estrogens exert a wide variety of actions on reproductive and non-reproductive functions. These effects are mediated by slow and long lasting genomic as well as rapid and transient non-genomic mechanisms. Besides the host of studies demonstrating the role of genomic actions at the physiological and behavioral level, m...
journal_title:Brain research
pub_type: 杂志文章,评审
doi:10.1016/j.brainres.2006.07.098
更新日期:2006-12-18 00:00:00
abstract:OBJECTIVE:The modern brain imaging studies in patients with eating disorders have shown that neurotransmitting regulation differs distinctly from control groups. These disturbances have involved serotonin and dopamine system can be inherited and conditioned by genes. The aim of this work has been the analysis of associ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2009.10.035
更新日期:2010-01-11 00:00:00
abstract::Increasing evidences show that hippocampal synaptic plasticity plays a crucial role in the pathogenesis of depression. The objective of this study was to determine whether electroacupuncture (EA) in the Wistar Kyoto (WKY) rat model of depression would exert antidepressant effects and whether this effect would be assoc...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2015.10.033
更新日期:2015-12-10 00:00:00
abstract::Chronic pain conditions such as rheumatoid arthritis and fibromyalgia are associated with profound hypothalamo-pituitary-adrenal (HPA) axis dysfunction which may exacerbate symptoms of chronic pain. HPA axis dysfunction has also been well documented in animal models of chronic inflammatory pain. However, the role of t...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2005.03.005
更新日期:2005-05-24 00:00:00
abstract::A combined retrograde transport and immunocytochemical study was carried out to determine the projections of the large glycine-immunoreactive neurons in the ventral cochlear nucleus of the guinea pig. Horseradish peroxidase (HRP) was injected into the contralateral cochlear nucleus, and cochlear nucleus sections were ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(87)90285-x
更新日期:1987-07-07 00:00:00
abstract::Dopamine neurons are overstimulated by drugs of abuse and suffer molecular alterations that lead to addiction behavior. Nurr1 is a transcription factor crucial for dopamine neurons survival and dopamine production, activating the transcription of key genes like tyrosine hydroxylase (TH). Interestingly, nuclear factor-...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2016.09.031
更新日期:2016-12-01 00:00:00
abstract::Cell number and proliferation of reactive astrocytes were studied quantitatively in the stabbed cerebral cortex of adult mice, using immunohistochemistry for glial fibrillary acidic protein (GFAP) and [3H]thymidine autoradiography. GFAP-positive astrocytes increased in cell number gradually from 24 to 96 h after stabb...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(88)90757-3
更新日期:1988-06-07 00:00:00
abstract::Tritiated thymidine ([3H]TdR) autoradiography revealed a correlation between the rate of cell proliferation of rod precursor cells in the outer nuclear layer (ONL) of the goldfish retina and the postoperative interval after crush of the optic nerve (ONC). Ten days after unilateral ONC there were more labeled nuclei in...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(89)90642-2
更新日期:1989-11-06 00:00:00
abstract::The role of subcortical input and/or output pathways in the development of cortical networks was examined in organotypic tissue cultures derived from neonatal mouse brain. Comparisons were made between cultures of cerebral neocortex grown with large amounts of subcortical tissue and those that were completely isolated...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(86)91631-8
更新日期:1986-02-19 00:00:00
abstract::Cholecystokinin-octapeptide-like-immunoreactivity (CCK-8-LI) is demonstrable by the indirect immunofluorescent technique in cerebral cortical neurons cultured from fetal rats. Prominent and widespread staining is seen in widely ramifying cellular processes throughout the cultures. Staining in neuronal cell bodies is e...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(84)91456-2
更新日期:1984-02-13 00:00:00
abstract::The retinoblastoma protein (pRb) is a key regulator of cell growth, differentiation and survival. pRb(-/-) mice show abnormal neuronal cell death in the developing brain. The function of pRb is regulated by its phosphorylation state. In this study, the phosphorylation of pRb during retinoic acid (RA)-induced neuronal ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(99)01844-2
更新日期:1999-09-25 00:00:00