Evidence for a glycinergic pathway connecting the two cochlear nuclei: an immunocytochemical and retrograde transport study.

Abstract:

:A combined retrograde transport and immunocytochemical study was carried out to determine the projections of the large glycine-immunoreactive neurons in the ventral cochlear nucleus of the guinea pig. Horseradish peroxidase (HRP) was injected into the contralateral cochlear nucleus, and cochlear nucleus sections were developed for HRP activity followed by staining for glycine using affinity-purified anti-glycine antibodies. These studies show that glycine-immunoreactive neurons in the ventral cochlear nucleus project to the contralateral cochlear nucleus and suggest that this pathway may be glycinergic.

journal_name

Brain Res

journal_title

Brain research

authors

Wenthold RJ

doi

10.1016/0006-8993(87)90285-x

subject

Has Abstract

pub_date

1987-07-07 00:00:00

pages

183-7

issue

1

eissn

0006-8993

issn

1872-6240

pii

0006-8993(87)90285-X

journal_volume

415

pub_type

杂志文章
  • Induction of NADPH-diaphorase activity in the rat periaqueductal gray matter after nociceptive visceral stimulation.

    abstract::Nitric oxide (NO) is a neuronal messenger that it is thought to be involved in the nociceptive transmission modulation. The activity of nicotinamide adenine dinucleotide phosphate diaphorase (NADPH-d) was shown to be identical to NOS activity in the brain. Since the periaqueductal gray matter (PAG) plays an important ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(98)00255-8

    authors: Rodella L,Rezzani R,Agostini C,Bianchi R

    更新日期:1998-05-18 00:00:00

  • Ascending dopaminergic projections from the dorsal raphe nucleus in the rat.

    abstract::The projections of putative dopamine containing cells within the dorsal raphe nucleus (DR) were studied using a combination of tyrosine hydroxylase (TH) immunocytochemistry and fluorescent retrograde tracing. Substantial numbers of TH-immunoreactive cells in the DR were found to project to the nucleus accumbens. Progr...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(90)90239-8

    authors: Stratford TR,Wirtshafter D

    更新日期:1990-03-12 00:00:00

  • In vitro and in vivo interactions between glioma and marrow-isolated adult multilineage inducible (MIAMI) cells.

    abstract::The prognosis of patients with malignant glioma remains extremely poor despite surgery and improvements in radio- and chemo-therapies. We recently showed that marrow-isolated adult mutilineage inducible (MIAMI) cells, a subpopulation of human mesenchymal stromal cells (MSCs), can serve as cellular carriers of drug-loa...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2012.07.030

    authors: Roger M,Clavreul A,Sindji L,Chassevent A,Schiller PC,Montero-Menei CN,Menei P

    更新日期:2012-09-14 00:00:00

  • Physical aggression and attentional bias to angry faces: An event related potential study.

    abstract::This study aimed to identify the neural correlates of aggression-related attentional selectivity to angry faces in physical aggression. Physical aggression in a non-clinical sample of young men (N = 36) was measured using an aggression questionnaire. Visual attentional bias to angry faces was assessed using a dot-prob...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2019.146387

    authors: Crago RV,Renoult L,Biggart L,Nobes G,Satmarean T,Bowler JO

    更新日期:2019-11-15 00:00:00

  • The recovery of blood-nerve barrier in crush nerve injury--a quantitative analysis utilizing immunohistochemistry.

    abstract::The purpose of this study is to reveal whether the application of immunohistochemical examinations to the peripheral nervous system (PNS) can be a reliable method for the quantitative analysis of the blood-nerve barrier (BNB) and the relationship between restoration of BNB and nerve regeneration. Sciatic nerves in rat...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2003.10.067

    authors: Omura K,Ohbayashi M,Sano M,Omura T,Hasegawa T,Nagano A

    更新日期:2004-03-19 00:00:00

  • Effect of olfactory bulb kindling on evoked potentials in the pyriform cortex.

    abstract::The potential evoked in the pyriform cortex by single-pulse stimulation of the olfactory bulb was examined before and after single and repeated elicitation of an epileptiform afterdischarge produced by stimulation of the olfactory bulb. A single afterdischarge (AD) produced a rapid (i.e. within 5 min) increase in the ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(85)91275-2

    authors: Russell RD,Stripling JS

    更新日期:1985-12-30 00:00:00

  • Genetic correlations among inbred strain sensitivities to convulsions induced by 9 convulsant drugs.

    abstract::Inbred mouse strains differed significantly in sensitivity to convulsions induced by 9 convulsant drugs administered using a timed infusion procedure. Some strains (e.g. BALB/cJ, A/J) were generally seizure-susceptible, while some were generally seizure resistant (e.g. C57BL/6J, SWR/J). However, the overall pattern of...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(90)90243-5

    authors: Kosobud AE,Crabbe JC

    更新日期:1990-08-27 00:00:00

  • Stimulus-related correlations between medial gastrocnemius muscle tension and homonymous motoneuron membrane potential result from non-linearities.

    abstract::In anesthetized cats, medial gastrocnemius motor units (MUs) were electrically stimulated via their ventral-root axons with independent random patterns. Muscle tension and homonymous alpha-motoneuron (alpha-MN) membrane potential fluctuations in response to these stimuli were recorded simultaneously. Cross-correlating...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(85)90763-2

    authors: Koehler W,Hamm TM,Enoka RM,Stuart DG,Windhorst U

    更新日期:1985-09-23 00:00:00

  • Protection of nigral cell death by bilateral subthalamic nucleus stimulation.

    abstract::In Parkinson disease (PD), the subthalamic nucleus (STN) becomes hyperactive (disinhibited), which is reported to cause excitotoxic damage to midbrain dopaminergic neurons. Here, we examined whether silencing of the hyperactive STN by chronic bilateral deep brain stimulation (DBS) increased the survival of midbrain do...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2006.08.082

    authors: Temel Y,Visser-Vandewalle V,Kaplan S,Kozan R,Daemen MA,Blokland A,Schmitz C,Steinbusch HW

    更新日期:2006-11-20 00:00:00

  • Dopamine decreases the calcium-activated afterhyperpolarization in hippocampal CA1 pyramidal cells.

    abstract::The effect of dopamine (DA) on the calcium-activated potassium conductance underlying the slow afterhyperpolarization (AHP) which follows a train of action potentials in hippocampal pyramidal cells was studied utilizing the in vitro hippocampal slice preparation. Bath-applied DA (1-100 microM) significantly reduced th...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(86)90773-0

    authors: Malenka RC,Nicoll RA

    更新日期:1986-08-06 00:00:00

  • Protein kinase C gamma-like immunoreactivity of trigeminothalamic neurons in the medullary dorsal horn of the rat.

    abstract::We examined protein kinase C gamma-like immunoreactivity (PKCgamma-LI) of trigeminothalamic neurons in the rat medullary dorsal horn (MDH) after injecting a retrograde tracer, Fluoro-Gold (FG), into the thalamus. Over 90% of FG-labeled neurons in the marginal layer (lamina I) and a few FG-labeled neurons in the superf...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(01)02777-9

    authors: Li YQ,Li JL,Li H,Kaneko T,Mizuno N

    更新日期:2001-09-21 00:00:00

  • Studies on cellular toxicity of bilirubin: effect on brain glycolysis in the young rat.

    abstract::(1) The levels of glycolytic intermediates in the brain tissue of 15-day-old homozygous and heterozygous Gunn rats were determined with or without novobiocin treatment in vivo, and the inhibitory effects of bilirubin on the glycolytic activity and the key glycolytic enzyme activities were investigated in vitro. (2) t...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(76)90945-8

    authors: Katoh-Semba R

    更新日期:1976-08-27 00:00:00

  • The network-selective actions of quinoxalines on the neurocircuitry operations of the rabbit retina.

    abstract::We examined the contribution of N-methyl-D-aspartate (NMDA) and alpha-amino-3-hydroxy-5-methyl-4-isoxalole-4-propionic acid (AMPA)/kainate (KA) receptors to the light-responses of rabbit retinal neurons. In the outer retina, bath application of the AMPA/KA receptor antagonists 6,7-dinitro-quinoxaline-2,3-dione (DNQX) ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(99)01448-1

    authors: Cohen ED,Miller RF

    更新日期:1999-06-12 00:00:00

  • Stimulation-dependent release of adenosine triphosphate from hippocampal slices.

    abstract::Schaffer collaterals of rat and mouse hippocampal slices were stimulated with bursts of pulses (300 Hz for 50 ms, 2-s intervals) for 30-s which caused a stable increase in the size of the population spike known as long-term potentiation. The release of adenosine triphosphate (ATP) was measured with a luciferase-lucife...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(89)90567-2

    authors: Wieraszko A,Goldsmith G,Seyfried TN

    更新日期:1989-04-24 00:00:00

  • Thrombin inhibition attenuates neurodegeneration and cerebral edema formation following transient forebrain ischemia.

    abstract::The disturbance of microcirculation following cerebral ischemia leads to an enlargement of cerebral infarct volume. Endogenous thrombin may play a role in this disturbance of microcirculation following cerebral ischemia. Therefore, the inhibition of thrombin may improve neurodegeneration and the accumulation of cerebr...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(01)02354-x

    authors: Ohyama H,Hosomi N,Takahashi T,Mizushige K,Kohno M

    更新日期:2001-06-01 00:00:00

  • Functional rescue of the inactive splice variant of the dopamine D3 receptor D3nf.

    abstract::We previously found that the dopamine D3 receptor can be split at the third cytoplasmic loop into two fragments (D3trunk and D3tail), and that the mixture of the two fragments retains the binding and functional activity of the wild type receptor. The dopamine D3 receptor gene gives rise to several inactive receptor sp...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(03)03360-2

    authors: Scarselli M,Novi F,Corsini GU,Maggio R

    更新日期:2003-10-17 00:00:00

  • Human neural stem cells improve sensorimotor deficits in the adult rat brain with experimental focal ischemia.

    abstract::Ischemic stroke is caused by the interruption of cerebral blood flow that leads to brain damage with long-term sensorimotor deficits. Stem cell transplantation may recover functional deficit by replacing damaged brain. In this study, we attempted to test whether the human neural stem cells (NSCs) can improve the outco...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2004.04.038

    authors: Chu K,Kim M,Park KI,Jeong SW,Park HK,Jung KH,Lee ST,Kang L,Lee K,Park DK,Kim SU,Roh JK

    更新日期:2004-08-06 00:00:00

  • Parameters of retinal graft-mediated responses are related to underlying target innervation.

    abstract::Retinae taken from embryonic mice were transplanted to the brain of newborn rats. One eye was removed from the recipients at this time to promote innervation of host visual centers. After 4-6 weeks the optic nerve of the remaining eye was transected to eliminate all visual afferents of host origin and 4-6 days later t...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(90)91338-h

    authors: Klassen H,Lund RD

    更新日期:1990-11-19 00:00:00

  • Histamine H1 receptors in UC-11MG astrocytes and their regulation of cytoplasmic Ca2+.

    abstract::Experiments were carried out on UC-11MG human astrocytoma cells, a continuous cell line that expresses a broad range of the biochemical and electrophysiological properties found in well-differentiated astrocytes. Because of a number of recent reports that astrocytes may express receptors for a variety of neuro-active ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(92)91676-6

    authors: Lucherini MJ,Gruenstein E

    更新日期:1992-10-02 00:00:00

  • Embryonic neural transplants across a major histocompatibility barrier: survival and specificity of innervation.

    abstract::The ability of embryonic tissue to survive cross-transplantation between histologically incompatible rat strains was examined by transplanting septal neurons from Sprague Dawley fetuses to adult Wistar rats (Ag-B6 to Ag-B2 histocompatibility haplotype). Transplants were found to survive without rejection over a period...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(83)91028-4

    authors: Low WC,Lewis PR,Terri ST

    更新日期:1983-03-07 00:00:00

  • Evidence for the movement of fluid, macromolecules and ions from the brain extracellular space to the CSF.

    abstract::This report examines the effect of decreasing serum osmolality on movement into the ventricular system of fluid and of test material injected into the brain. Trace quantities of 22NaCl and 125I-labeled cat serum albumin (CSA) were injected into cerebral white matter of cats. The rates of cerebrospinal fluid volume flo...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(78)90885-5

    authors: Wald A,Hochwald GM,Gandhi M

    更新日期:1978-08-04 00:00:00

  • Enhancement of noradrenergic neurotransmission in the nucleus of the solitary tract modulates memory storage processes.

    abstract::These studies examined whether posttraining activation of alpha1-noradrenergic receptors in the nucleus tractus solitarius (NTS) influences neural processes that are involved in encoding information into memory. Different groups of male Sprague-Dawley rats were trained in two separate learning tasks. In experiment 1, ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(03)03323-7

    authors: Miyashita T,Williams CL

    更新日期:2003-10-17 00:00:00

  • Blockade of NMDA receptor-mediated mobilization of intracellular Ca2+ prevents neurotoxicity.

    abstract::NMDA receptor activation leads to elevated Ca2+ in cultured rat cortical and retinal ganglion cell neurons. If excessive, this Ca2+ response is associated with delayed neurotoxicity. We used dantrolene and ionomycin to test if the Ca2+ response to NMDA was due to mobilization of intracellular Ca2+ stores rather than m...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(92)90183-a

    authors: Lei SZ,Zhang D,Abele AE,Lipton SA

    更新日期:1992-12-11 00:00:00

  • Deposition of collagen IV and aggrecan in leptomeningeal arteries of hereditary brain haemorrhage with amyloidosis.

    abstract::Hereditary Cystatin C Amyloid Angiopathy (HCCAA) is a rare genetic disease in Icelandic families caused by a mutation in the cystatin C gene, CST3. HCCAA is classified as a cerebral amyloid angiopathy and mutant cystatin C forms amyloid deposits in cerebral arteries resulting in fatal haemorrhagic strokes in young adu...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2013.08.029

    authors: Snorradottir AO,Isaksson HJ,Kaeser SA,Skodras AA,Olafsson E,Palsdottir A,Bragason BT

    更新日期:2013-10-16 00:00:00

  • Dopamine receptor-mediated inhibition of serotonin N-acetyltransferase activity in retina.

    abstract::The possible involvement of catecholamines in the regulation of serotonin N-acetyltransferase (NAT) activity in retina of the African clawed frog was investigated using an in vitro eye cup preparation. Dopamine (10 microM) and norepinephrine (50 microM) had no significant effect on NAT activity of eye cups incubated i...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(86)90525-1

    authors: Iuvone PM,Besharse JC

    更新日期:1986-03-26 00:00:00

  • Evidence for elevated nicotine-induced structural plasticity in nucleus accumbens of adolescent rats.

    abstract::Male Long-Evans rats were administered nicotine bitartrate or sodium tartrate either during adolescence (p29-43) or adulthood (p80-94). Route of administration was via subcutaneously implanted osmotic pump (initial dose 2.0 mg/kg/day, free base). Five weeks following nicotine administration, brains were processed for ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2007.03.019

    authors: McDonald CG,Eppolito AK,Brielmaier JM,Smith LN,Bergstrom HC,Lawhead MR,Smith RF

    更新日期:2007-06-02 00:00:00

  • Intrathecal cyclosporin prolongs survival of late-stage ALS mice.

    abstract::Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by upper and lower motor neuron death with ascending paralysis leading to death. In a transgenic mouse model of ALS (SOD1-G93A) weakness appears at 3 months of age, and because of progressive paralysis leads to death by 5 months. Cyclospo...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(01)02012-1

    authors: Keep M,Elmér E,Fong KS,Csiszar K

    更新日期:2001-03-16 00:00:00

  • Physostigmine and acetylcholine differentially activate nicotinic receptor subpopulations in Locusta migratoria neurons.

    abstract::The effects of acetylcholine (ACh) and physostigmine (PHY) on thoracic ganglion neurons of Locusta migratoria were investigated using whole-cell and cell-attached voltage clamp. ACh activated whole-cell currents with variable amplitudes, time course and ion channel block between cells, suggesting differential expressi...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(98)00007-9

    authors: van den Beukel I,van Kleef RG,Zwart R,Oortgiesen M

    更新日期:1998-04-13 00:00:00

  • Diurnal rhythm of neuropeptide Y-like immunoreactivity in the suprachiasmatic, arcuate and paraventricular nuclei and other hypothalamic sites.

    abstract::The diurnal rhythm of neuropeptide Y (NPY)-like immunoreactivity was examined in 9 discrete hypothalamic sites of rats maintained on a 12:12 h light/dark cycle. Significant bimodal rhythms of NPY concentration were detected in the suprachiasmatic and arcuate nuclei, with significant peaks just prior to onset of the no...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(90)90045-d

    authors: Jhanwar-Uniyal M,Beck B,Burlet C,Leibowitz SF

    更新日期:1990-12-17 00:00:00

  • Immunocytochemical localisation of neuropeptide Y and 5-hydroxytryptamine in a subpopulation of amine-handling intracardiac neurones that do not contain dopamine beta-hydroxylase in tissue culture.

    abstract::The colocalisation of neuropeptide Y (NPY)- and 5-hydroxytryptamine (5-HT)-immunoreactivities in intracardiac neurones in dissociated cultures from the atria and interatrial septum of newborn guinea pig heart was demonstrated by the sequential application of specific antisera which were visualised by two different flu...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(87)90541-5

    authors: Hassall CJ,Burnstock G

    更新日期:1987-09-29 00:00:00