Abstract:
:A combined retrograde transport and immunocytochemical study was carried out to determine the projections of the large glycine-immunoreactive neurons in the ventral cochlear nucleus of the guinea pig. Horseradish peroxidase (HRP) was injected into the contralateral cochlear nucleus, and cochlear nucleus sections were developed for HRP activity followed by staining for glycine using affinity-purified anti-glycine antibodies. These studies show that glycine-immunoreactive neurons in the ventral cochlear nucleus project to the contralateral cochlear nucleus and suggest that this pathway may be glycinergic.
journal_name
Brain Resjournal_title
Brain researchauthors
Wenthold RJdoi
10.1016/0006-8993(87)90285-xsubject
Has Abstractpub_date
1987-07-07 00:00:00pages
183-7issue
1eissn
0006-8993issn
1872-6240pii
0006-8993(87)90285-Xjournal_volume
415pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract::Nitric oxide (NO) is a neuronal messenger that it is thought to be involved in the nociceptive transmission modulation. The activity of nicotinamide adenine dinucleotide phosphate diaphorase (NADPH-d) was shown to be identical to NOS activity in the brain. Since the periaqueductal gray matter (PAG) plays an important ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(98)00255-8
更新日期:1998-05-18 00:00:00
abstract::The projections of putative dopamine containing cells within the dorsal raphe nucleus (DR) were studied using a combination of tyrosine hydroxylase (TH) immunocytochemistry and fluorescent retrograde tracing. Substantial numbers of TH-immunoreactive cells in the DR were found to project to the nucleus accumbens. Progr...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(90)90239-8
更新日期:1990-03-12 00:00:00
abstract::The prognosis of patients with malignant glioma remains extremely poor despite surgery and improvements in radio- and chemo-therapies. We recently showed that marrow-isolated adult mutilineage inducible (MIAMI) cells, a subpopulation of human mesenchymal stromal cells (MSCs), can serve as cellular carriers of drug-loa...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2012.07.030
更新日期:2012-09-14 00:00:00
abstract::This study aimed to identify the neural correlates of aggression-related attentional selectivity to angry faces in physical aggression. Physical aggression in a non-clinical sample of young men (N = 36) was measured using an aggression questionnaire. Visual attentional bias to angry faces was assessed using a dot-prob...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2019.146387
更新日期:2019-11-15 00:00:00
abstract::The purpose of this study is to reveal whether the application of immunohistochemical examinations to the peripheral nervous system (PNS) can be a reliable method for the quantitative analysis of the blood-nerve barrier (BNB) and the relationship between restoration of BNB and nerve regeneration. Sciatic nerves in rat...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2003.10.067
更新日期:2004-03-19 00:00:00
abstract::The potential evoked in the pyriform cortex by single-pulse stimulation of the olfactory bulb was examined before and after single and repeated elicitation of an epileptiform afterdischarge produced by stimulation of the olfactory bulb. A single afterdischarge (AD) produced a rapid (i.e. within 5 min) increase in the ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(85)91275-2
更新日期:1985-12-30 00:00:00
abstract::Inbred mouse strains differed significantly in sensitivity to convulsions induced by 9 convulsant drugs administered using a timed infusion procedure. Some strains (e.g. BALB/cJ, A/J) were generally seizure-susceptible, while some were generally seizure resistant (e.g. C57BL/6J, SWR/J). However, the overall pattern of...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(90)90243-5
更新日期:1990-08-27 00:00:00
abstract::In anesthetized cats, medial gastrocnemius motor units (MUs) were electrically stimulated via their ventral-root axons with independent random patterns. Muscle tension and homonymous alpha-motoneuron (alpha-MN) membrane potential fluctuations in response to these stimuli were recorded simultaneously. Cross-correlating...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(85)90763-2
更新日期:1985-09-23 00:00:00
abstract::In Parkinson disease (PD), the subthalamic nucleus (STN) becomes hyperactive (disinhibited), which is reported to cause excitotoxic damage to midbrain dopaminergic neurons. Here, we examined whether silencing of the hyperactive STN by chronic bilateral deep brain stimulation (DBS) increased the survival of midbrain do...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2006.08.082
更新日期:2006-11-20 00:00:00
abstract::The effect of dopamine (DA) on the calcium-activated potassium conductance underlying the slow afterhyperpolarization (AHP) which follows a train of action potentials in hippocampal pyramidal cells was studied utilizing the in vitro hippocampal slice preparation. Bath-applied DA (1-100 microM) significantly reduced th...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(86)90773-0
更新日期:1986-08-06 00:00:00
abstract::We examined protein kinase C gamma-like immunoreactivity (PKCgamma-LI) of trigeminothalamic neurons in the rat medullary dorsal horn (MDH) after injecting a retrograde tracer, Fluoro-Gold (FG), into the thalamus. Over 90% of FG-labeled neurons in the marginal layer (lamina I) and a few FG-labeled neurons in the superf...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(01)02777-9
更新日期:2001-09-21 00:00:00
abstract::(1) The levels of glycolytic intermediates in the brain tissue of 15-day-old homozygous and heterozygous Gunn rats were determined with or without novobiocin treatment in vivo, and the inhibitory effects of bilirubin on the glycolytic activity and the key glycolytic enzyme activities were investigated in vitro. (2) t...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(76)90945-8
更新日期:1976-08-27 00:00:00
abstract::We examined the contribution of N-methyl-D-aspartate (NMDA) and alpha-amino-3-hydroxy-5-methyl-4-isoxalole-4-propionic acid (AMPA)/kainate (KA) receptors to the light-responses of rabbit retinal neurons. In the outer retina, bath application of the AMPA/KA receptor antagonists 6,7-dinitro-quinoxaline-2,3-dione (DNQX) ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(99)01448-1
更新日期:1999-06-12 00:00:00
abstract::Schaffer collaterals of rat and mouse hippocampal slices were stimulated with bursts of pulses (300 Hz for 50 ms, 2-s intervals) for 30-s which caused a stable increase in the size of the population spike known as long-term potentiation. The release of adenosine triphosphate (ATP) was measured with a luciferase-lucife...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(89)90567-2
更新日期:1989-04-24 00:00:00
abstract::The disturbance of microcirculation following cerebral ischemia leads to an enlargement of cerebral infarct volume. Endogenous thrombin may play a role in this disturbance of microcirculation following cerebral ischemia. Therefore, the inhibition of thrombin may improve neurodegeneration and the accumulation of cerebr...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(01)02354-x
更新日期:2001-06-01 00:00:00
abstract::We previously found that the dopamine D3 receptor can be split at the third cytoplasmic loop into two fragments (D3trunk and D3tail), and that the mixture of the two fragments retains the binding and functional activity of the wild type receptor. The dopamine D3 receptor gene gives rise to several inactive receptor sp...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(03)03360-2
更新日期:2003-10-17 00:00:00
abstract::Ischemic stroke is caused by the interruption of cerebral blood flow that leads to brain damage with long-term sensorimotor deficits. Stem cell transplantation may recover functional deficit by replacing damaged brain. In this study, we attempted to test whether the human neural stem cells (NSCs) can improve the outco...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2004.04.038
更新日期:2004-08-06 00:00:00
abstract::Retinae taken from embryonic mice were transplanted to the brain of newborn rats. One eye was removed from the recipients at this time to promote innervation of host visual centers. After 4-6 weeks the optic nerve of the remaining eye was transected to eliminate all visual afferents of host origin and 4-6 days later t...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(90)91338-h
更新日期:1990-11-19 00:00:00
abstract::Experiments were carried out on UC-11MG human astrocytoma cells, a continuous cell line that expresses a broad range of the biochemical and electrophysiological properties found in well-differentiated astrocytes. Because of a number of recent reports that astrocytes may express receptors for a variety of neuro-active ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(92)91676-6
更新日期:1992-10-02 00:00:00
abstract::The ability of embryonic tissue to survive cross-transplantation between histologically incompatible rat strains was examined by transplanting septal neurons from Sprague Dawley fetuses to adult Wistar rats (Ag-B6 to Ag-B2 histocompatibility haplotype). Transplants were found to survive without rejection over a period...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(83)91028-4
更新日期:1983-03-07 00:00:00
abstract::This report examines the effect of decreasing serum osmolality on movement into the ventricular system of fluid and of test material injected into the brain. Trace quantities of 22NaCl and 125I-labeled cat serum albumin (CSA) were injected into cerebral white matter of cats. The rates of cerebrospinal fluid volume flo...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(78)90885-5
更新日期:1978-08-04 00:00:00
abstract::These studies examined whether posttraining activation of alpha1-noradrenergic receptors in the nucleus tractus solitarius (NTS) influences neural processes that are involved in encoding information into memory. Different groups of male Sprague-Dawley rats were trained in two separate learning tasks. In experiment 1, ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(03)03323-7
更新日期:2003-10-17 00:00:00
abstract::NMDA receptor activation leads to elevated Ca2+ in cultured rat cortical and retinal ganglion cell neurons. If excessive, this Ca2+ response is associated with delayed neurotoxicity. We used dantrolene and ionomycin to test if the Ca2+ response to NMDA was due to mobilization of intracellular Ca2+ stores rather than m...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(92)90183-a
更新日期:1992-12-11 00:00:00
abstract::Hereditary Cystatin C Amyloid Angiopathy (HCCAA) is a rare genetic disease in Icelandic families caused by a mutation in the cystatin C gene, CST3. HCCAA is classified as a cerebral amyloid angiopathy and mutant cystatin C forms amyloid deposits in cerebral arteries resulting in fatal haemorrhagic strokes in young adu...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2013.08.029
更新日期:2013-10-16 00:00:00
abstract::The possible involvement of catecholamines in the regulation of serotonin N-acetyltransferase (NAT) activity in retina of the African clawed frog was investigated using an in vitro eye cup preparation. Dopamine (10 microM) and norepinephrine (50 microM) had no significant effect on NAT activity of eye cups incubated i...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(86)90525-1
更新日期:1986-03-26 00:00:00
abstract::Male Long-Evans rats were administered nicotine bitartrate or sodium tartrate either during adolescence (p29-43) or adulthood (p80-94). Route of administration was via subcutaneously implanted osmotic pump (initial dose 2.0 mg/kg/day, free base). Five weeks following nicotine administration, brains were processed for ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2007.03.019
更新日期:2007-06-02 00:00:00
abstract::Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by upper and lower motor neuron death with ascending paralysis leading to death. In a transgenic mouse model of ALS (SOD1-G93A) weakness appears at 3 months of age, and because of progressive paralysis leads to death by 5 months. Cyclospo...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(01)02012-1
更新日期:2001-03-16 00:00:00
abstract::The effects of acetylcholine (ACh) and physostigmine (PHY) on thoracic ganglion neurons of Locusta migratoria were investigated using whole-cell and cell-attached voltage clamp. ACh activated whole-cell currents with variable amplitudes, time course and ion channel block between cells, suggesting differential expressi...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(98)00007-9
更新日期:1998-04-13 00:00:00
abstract::The diurnal rhythm of neuropeptide Y (NPY)-like immunoreactivity was examined in 9 discrete hypothalamic sites of rats maintained on a 12:12 h light/dark cycle. Significant bimodal rhythms of NPY concentration were detected in the suprachiasmatic and arcuate nuclei, with significant peaks just prior to onset of the no...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(90)90045-d
更新日期:1990-12-17 00:00:00
abstract::The colocalisation of neuropeptide Y (NPY)- and 5-hydroxytryptamine (5-HT)-immunoreactivities in intracardiac neurones in dissociated cultures from the atria and interatrial septum of newborn guinea pig heart was demonstrated by the sequential application of specific antisera which were visualised by two different flu...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(87)90541-5
更新日期:1987-09-29 00:00:00