Serotonin receptor gene expression in the rat suprachiasmatic nuclei.

abstract：:The enzymatic and regulatory properties of Ca2+/calmodulin-dependent protein kinase in the postsynaptic density (mPSDp CaM kinase) of the rat forebrain was compared with those of soluble Ca2+/calmodulin-dependent protein kinase II (CaM kinase II). mPSDp CaM kinase was different from soluble CaM kinase II in terms of s...

journal_title：Brain research

authors： Ochiishi T,Sugiura H,Yamauchi T

更新日期：1993-04-30 00:00:00

abstract：:Neurophysiological responses were recorded in individual fibers of the lingual and chorda tympani nerves and in single cortical neurons in the rat in response to a battery of tactile, thermal and chemical stimuli applied to the oral cavity. Two categories of thermally sensitive units were identified. Chorda tympani fi...

journal_title：Brain research

authors： Kosar E,Schwartz GJ

更新日期：1990-04-16 00:00:00

abstract：:Neonatal rats were given capsaicin subcutaneously. Controls received vehicle only. Six months later the nerve fiber populations in the dorsal root L4, in the inferior alveolar nerve and in mandibular molar pulps were examined by electron microscopy. The proportion of unmyelinated axons was found to be markedly decreas...

journal_title：Brain research

authors： Holje L,Hildebrand C,Fried K

更新日期：1983-04-25 00:00:00

abstract：:Using biochemical techniques we determined concentrations of the AMPA-selective glutamate receptor subunits GluR1 and GluR2/3 in the entorhinal cortex of patients with Alzheimer's disease pathology and age-matched controls. Tangle density was also determined in anatomically matched samples and correlated with GluR1 an...

journal_title：Brain research

authors： Yasuda RP,Ikonomovic MD,Sheffield R,Rubin RT,Wolfe BB,Armstrong DM

更新日期：1995-04-24 00:00:00

abstract：:Rats exposed to inescapable tailshock exhibit deficits in learning a simple shuttlebox escape task 24 h later. This syndrome has been termed 'behavioral depression' or 'learned helplessness', and is a model of stress-induced depression. In the present study a significant (25%) decrease in GABA receptor-mediated chlori...

journal_title：Brain research

authors： Drugan RC,Morrow AL,Weizman R,Weizman A,Deutsch SI,Crawley JN,Paul SM

更新日期：1989-05-15 00:00:00

abstract：:Neurotensin (NT), a tridecapeptide, is a neurotransmitter that elicits potent effects including hypothermia and antinociception in mice and rats. To date, there are two types of the neurotensin receptor (NTR) that have been molecularly cloned from the rat. However, several lines of evidence suggest the presence of add...

journal_title：Brain research

authors： Tyler BM,Cusack B,Douglas CL,Souder T,Richelson E

更新日期：1998-05-11 00:00:00

abstract：:The present study investigated whether the effects of central cholinergic stimulation on thermoregulation during exercise are modulated by arterial baroreceptors. Wistar rats were submitted to sinoaortic denervation (SAD) or sham denervation (SHAM) and then fitted with a chronic guide cannula into the lateral cerebral...

journal_title：Brain research

authors： Pires W,Wanner SP,Lima MR,Oliveira BM,Guimarães JB,de Lima DC,Haibara AS,Rodrigues LO,Coimbra CC,Lima NR

更新日期：2010-12-17 00:00:00

abstract：:Neurotrophins regulate many aspects of neuronal function and activity. Specifically, the binding of Brain-derived neurotrophic factor (BDNF) to Tyrosine receptor kinase-B (TrkB) or its truncated version, TrkB-T1, can cause growth and differentiation or dominant inhibition of receptor signaling, respectively. There is ...

journal_title：Brain research

authors： Brague JC,Swann JM

更新日期：2017-08-15 00:00:00

abstract：:Using the rapid Golgi method, the morphology of dendritic spines was quantified in the calyxes of groups of newly emerged, nurse, and forager honeybees. These groups were studied because they represented distinct stages of behavioral development and cumulative experience which, according to recent vertebrate findings,...

journal_title：Brain research

authors： Coss RG,Brandon JG,Globus A

更新日期：1980-06-16 00:00:00

abstract：:Intracellular recordings were made from rabbit nodose ganglion cells in vitro. Morphine (up to 100 micro M), normorphine (up to 10 micro M) and D-Ala2, Leu5-enkephalin (DADLE) (up to 5 micro M) each had no detectable effect on the electrical properties of the cell membrane, except for local anesthetic-like actions at ...

journal_title：Brain research

authors： Shefner SA,North RA,Zukin RS

更新日期：1981-09-21 00:00:00

abstract：:The present in vitro study was performed to characterize neurons within dorsal regions of the nucleus tractus solitarii (NTS), principally at the level of area postrema, and known to receive inputs predominantly from cardiovascular and respiratory afferents (i.e. cardiorespiratory NTS). This report describes 4 classes...

journal_title：Brain research

authors： Paton JF,Foster WR,Schwaber JS

更新日期：1993-02-26 00:00:00

abstract：:Histopathological analyses of brains of rats receiving a single 0.9 LD50 injection of soman, a potent anticholinesterase neurotoxin, revealed massive widespread lesions in the cerebral cortex and thalamus 4 weeks post-injection. Such lesions were not evidenced in rats receiving diazepam (2.2 mg/kg, i.m.) 10 min prior ...

journal_title：Brain research

authors： Martin LJ,Doebler JA,Shih TM,Anthony A

更新日期：1985-01-28 00:00:00

abstract：:Functionally activated sites usually have multiple specificities where coactivation is induced by inputs with different informational content. Using typical voxel-based functional mapping (univariate analysis), it is possible to show the presence of coactivation; however, it is not possible to distinguish whether coac...

journal_title：Brain research

authors： Sung YW,Choi SH,Hong SJ,Choi US,Cho JH,Ogawa S

更新日期：2010-12-17 00:00:00

abstract：:A major effect of volatile anesthetics is to reduce excitatory synaptic transmission. In the present study the stimulated release of glutamate under the influence of increasing concentrations of isoflurane was studied in vitro by utilizing hippocampal slices from Wistar rats. Ca(2+)-dependent release was calculated by...

journal_title：Brain research

authors： Larsen M,Grøndahl TO,Haugstad TS,Langmoen IA

更新日期：1994-11-14 00:00:00

abstract：:The purpose of the present study is to examine the effects of mental fatigue and motivation on neural network dynamics activated during task switching. Mental fatigue was induced by 2 h of continuous performance; after which subjects were motivated by using social comparison and monetary reward as motivating factors t...

journal_title：Brain research

authors： Lorist MM,Bezdan E,ten Caat M,Span MM,Roerdink JB,Maurits NM

更新日期：2009-05-13 00:00:00

abstract：:We have previously observed that chronic cocaine administration increases levels of adenylyl cyclase and cAMP-dependent protein kinase (PKA) in the nucleus accumbens (NAc). In the present work we directly examined the involvement of the cAMP system at the level of the NAc in cocaine-induced locomotor activity and sens...

journal_title：Brain research

authors： Miserendino MJ,Nestler EJ

更新日期：1995-03-20 00:00:00

abstract：:The neuropeptide nociceptin/orphanin FQ (N/OFQ), the endogenous agonist of the N/OFQ peptide receptor (NOP receptor), has been demonstrated to be involved in many physiological and pathological functions including pain regulation. In the present study, the involvement of N/OFQ-NOP receptor system in electroacupuncture...

journal_title：Brain research

authors： Fu X,Wang YQ,Wu GC

更新日期：2006-03-17 00:00:00

abstract：:L-3, 4-Dihydroxyphenylalanine (L-dopa) has been widely used for the treatment of Parkinson's disease (PD), but its pharmacokinetics in the striatum have hardly been investigated, especially in primates. In this study, we examined the concentration of L-dopa in plasma and in the extracellular fluid (ECF) of the striatu...

journal_title：Brain research

authors： Zhang J,Qu FR,Nakatsuka A,Nomura T,Nagai M,Nomoto M

更新日期：2003-12-12 00:00:00

abstract：:We have studied the effects of prenatal protein malnutrition on development of the hippocampal and frontal cortical electroencephalographic (EEG) activity. Using power spectral analyses in rats of several age groups we found that protein malnutrition, instituted prenatally and continued postnatally, produces marked al...

journal_title：Brain research

authors： Morgane PJ,Austin K,Siok C,LaFrance R,Bronzino JD

更新日期：1985-10-01 00:00:00

abstract：:Active substance P binding sites were solubilized from rat brain membranes by treatment with 0.125% sodium glycodeoxycholate and 1 M NaCl. About 50% of the binding activity in membrane-bound binding sites was recovered in the solubilized fraction after centrifugation at 105,000 g for 1 h. [3H]Substance P absorbed exte...

journal_title：Brain research

authors： Maruyama M

更新日期：1986-04-02 00:00:00

abstract：:N-Acetylated-alpha-linked acidic dipeptidase (NAALADase) hydrolyzes N-acetyl-aspartyl-glutamate (NAAG) to liberate N-acetyl-aspartate and glutamate. NAAG is a putative neurotransmitter and acts as a mixed agonist/antagonist on N-methyl-D-aspartate (NMDA) receptors and acts as an agonist on the metabotropic glutamate r...

journal_title：Brain research

authors： Yamamoto T,Nozaki-Taguchi N,Sakashita Y

更新日期：2001-08-03 00:00:00

abstract：:alpha-Adrenoreceptors are present in the ventricular (VZ) and subventricular (SVZ) zones of the mammalian embryonic forebrain, and contribute towards cell cycle controls in the germinal neuroepithelium [Pabbathi et al., Brain Res. 760 (1997) 22-33.]. Since noradrenaline-containing fibres from the locus coeruleus (LC) ...

journal_title：Brain research

authors： Popovik E,Haynes LW

更新日期：2000-01-24 00:00:00

abstract：:In the course of pulse-label studies on the axonal transport of the small, basic, actin-binding proteins--actin depolymerizing factor, cofilin and profilin--in chicken motor neurones, we observed a heavily labelled protein of M(r) 18 kDa and pI 8.2 on fluorographs of two-dimensional polyacrylamide gels. On the basis o...

journal_title：Brain research

authors： Yuan A,Mills RG,Bamburg JR,Bray JJ

更新日期：1997-10-17 00:00:00

abstract：:Several lines of evidence support a role for nerve growth factor (NGF) in the sympathetic sprouting response that occurs following septal cholinergic denervation of the rat hippocampal formation. The present study was undertaken to compare the distribution of NGF-like immunoreactivity and the topography of sympathetic...

journal_title：Brain research

authors： Yu C,Crutcher KA

更新日期：1995-02-20 00:00:00

abstract：:Alteration in the blood-nerve barrier may be of primary importance in the development of experimental lead neuropathy. Using quantitative track autoradiography, we have directly demonstrated that there is a 15-fold increase in the rate of 210Pb accumulation in the endoneurium 70 days after the onset of chronic intoxic...

journal_title：Brain research

authors： Windebank AJ,Dyck PJ

更新日期：1981-11-23 00:00:00

abstract：:The Snell dwarf mouse (dw/dw) shows significantly decreased somatostatin levels in the hypothalamus whereas more or less increased somatostatin concentrations are observed in any central extrahypothalamic sites studied. These opposite results in hypothalamus and extrahypothalamic areas may be linked to the apparently ...

journal_title：Brain research

authors： Fuhrmann G,Di Scala-Guenot D,Ebel A

更新日期：1985-02-25 00:00:00

abstract：:Central nervous system (CNS) disorders are important targets for gene therapy; however, delivery of therapeutic proteins and/or genes to the brain remains a major challenge due to the difficulty of efficiently delivering viral vectors across the blood-brain barrier (BBB). In the present work, we tested the ability of ...

journal_title：Brain research

authors： Miyake N,Miyake K,Yamamoto M,Hirai Y,Shimada T

更新日期：2011-05-10 00:00:00

abstract：:In previous studies we have tested the hypothesis that the termination of the period of sexual behavior in female guinea pigs results from the loss of progestin receptors from hypothalamic cell nuclei. We have shown that hormonal manipulations that delay heat termination also delay loss of hypothalamic nuclear progest...

journal_title：Brain research

authors： Brown TJ,Blaustein JD

更新日期：1986-05-14 00:00:00

abstract：:The present study was undertaken to investigate in rats the role of the noradrenergic innervation of the hippocampus in the reversal by antidepressant drugs of escape failures caused by previous exposure to inescapable shocks (learned helplessness design). Rats were either sham-operated or given a bilateral infusion o...

journal_title：Brain research

authors： Soubrie P,Martin P,el Mestikawy S,Hamon M

更新日期：1987-12-29 00:00:00

abstract：:Extracellular recordings were made in vitro from 212 single units in the rat subfornical organ (SFO) and 54 single units in the rat medial preoptic area (MPO). Units were exposed to solutions made hyper-osmotic or hypo-osmotic by 1.4-11%. A reversible 30% or greater change in frequency followed the osmotic challenge i...

journal_title：Brain research

authors： Sibbald JR,Hubbard JI,Sirett NE

更新日期：1988-10-04 00:00:00