Abstract：
:Neurophysiological responses were recorded in individual fibers of the lingual and chorda tympani nerves and in single cortical neurons in the rat in response to a battery of tactile, thermal and chemical stimuli applied to the oral cavity. Two categories of thermally sensitive units were identified. Chorda tympani fibers and one type of cortical unit ('Type I') were activated by cold water stimulation but were unaffected by warm water or menthol. In contrast, lingual fibers and a different category of cortical units ('Type II') were extremely sensitive to menthol exposure. These units were cold water sensitive, however, this sensitivity was suppressed following menthol presentation.
journal_name
Brain Resjournal_title
Brain researchauthors
Kosar E,Schwartz GJdoi
10.1016/0006-8993(90)90458-nsubject
Has Abstractpub_date
1990-04-16 00:00:00pages
202-11issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(90)90458-Njournal_volume
513pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract：:The purpose of this paper is to investigate the involvement of various auditory localization mechanisms in the improvement of auditory spatial sensitivity in the case of partial visual deprivation. We compared sensitivity to binaural, monaural, and echo cues between normal-sighted and myopic subjects. In an auditory t...
journal_title：Brain research
pub_type： 临床试验,杂志文章
doi：10.1016/j.brainres.2005.01.101
更新日期：2005-04-11 00:00:00
abstract：:This study is focused to learn about the cellular localization of transcription factors binding to the cAMP response element-CREBs-in the brain of normal rats and in animals subjected to excitotoxic cell damage. For this purpose, CREB-1 and CREB-2 immunoreactivity is examined in the developing and adult rat brain unde...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(95)01527-2
更新日期：1996-03-11 00:00:00
abstract：:The distribution of calretinin containing neurons examined by in situ hybridization mapping was compared with that obtained by immunocytochemistry in the brain of octopus. Results revealed a close correspondence between the two types of investigations. Western blot analysis disclosed a 29 kDa protein immunostained wit...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2006.11.056
更新日期：2007-02-09 00:00:00
abstract：:A startle-like response can be evoked at low currents by one-pulse electrical stimulation of reticular formation sites from the rostrolateral pons to the caudomedial medulla. To test whether this response is mediated by the same reticular formation neurons as those that mediate the acoustic startle, we delivered a bri...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)91100-7
更新日期：1993-07-23 00:00:00
abstract：:The N400 is an event-related potential (ERP) component that is elicited by semantically meaningful stimuli; one of its defining characteristics is that it is amplified for sentence completions that are semantically unexpected or incongruous with the preceding context. Some prior reports using visual sentence reading p...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2010.07.099
更新日期：2010-10-08 00:00:00
abstract：:The release of [3H]acetylcholine (ACh) from 6-, 8-, 10-, 12-, 14- and 16-day chick embryo neural retina layers was determined using a perfusion system to collect the released neurotransmitter. After labeling the tissue with [3H]choline, samples of [3H]ACh released before and after stimulation by 80 mM KCl or 5 mM glut...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0165-3806(82)90137-7
更新日期：1982-07-01 00:00:00
abstract：:FRAT1 was originally characterized as a protein frequently rearranged in advanced T cell lymphoma, which inhibits GSK-3-mediated phosphorylation of beta-catenin and positively regulates the Wnt signaling pathway. FRAT1 has been identified as a proto-oncogene involved in tumorigenesis. Previous studies have shown that ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2010.01.037
更新日期：2010-03-12 00:00:00
abstract：:Perinatal asphyxia to the developing brain remains a major cause of morbidity. Hypothermia is currently the only established neuroprotective treatment available for term born infants with hypoxic-ischemic encephalopathy, saving one in seven to eight infants from developing severe neurological deficits. Therefore, addi...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2016.05.040
更新日期：2016-09-01 00:00:00
abstract：:The amplitude of anterior neocortical EEG slow-waves (0.5-4 Hz) measured during quiet waking, drowsy (WS) and synchronized sleep (S) states showed slow rhythmic oscillations in WS and S similar to those previously reported in midbrain reticular neurons (periods of 8-12 s). Abrupt changes in slow rhythms of unit discha...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(83)90153-1
更新日期：1983-06-20 00:00:00
abstract：:To characterize properties and mechanisms of non-photic entrainment of circadian rhythms, the effects of scheduled feeding were assessed in intact and suprachiasmatic nuclei (SCN) ablated C57BL/6j mice. During ad libitum food access, mice with no or partial SCN damage exhibited free-running activity and drinking rhyth...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(97)00571-4
更新日期：1997-08-15 00:00:00
abstract：:Spontaneous alternation which is disrupted by lesion of septal dopaminergic (DA) afferents was chosen as a behavioral marker for the study of functional interactions between DA and noradrenergic (NA) innervation of the lateral septum. Three groups of rats were studied: a solvent group which received only vehicle injec...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(91)90669-m
更新日期：1991-06-21 00:00:00
abstract：:We have developed a RNA-RNA solution hybridization assay to quantitate the mRNA coding for prodynorphin precursor. This assay is extremely sensitive and highly specific. Using this assay we have measured the prodynorphin mRNA in various brain regions and reproductive tissues of rat. When we compared the distribution o...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(87)80011-2
更新日期：1987-07-01 00:00:00
abstract：:The activities of GABA-transaminase (GABA-T) were examined in several brain regions of amygdala-kindled rats, pretreated either with or without gabaculine, an irreversible GABA-T inhibitor. Histochemical and biochemical studies demonstrated that GABA-T activities decreased significantly in some brain regions 16 h afte...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(86)90692-x
更新日期：1986-08-27 00:00:00
abstract：:(1) Spontaneous barbiturate spindles were recorded from the primary and secondary somatosensory cortex. The recordings were concentrated to areas surrounding several reference loci. The recording sites producing the maximal response evoked by stimulation of an exposed nerve in a contralateral limb were used as referen...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(76)90984-7
更新日期：1976-01-09 00:00:00
abstract：:Dopamine (DA) and noradrenaline (NA) extracellular levels have been measured by microdialysis in the medial frontal cortex (MFC), nucleus accumbens (NAc) and caudate-putamen (CP) under baseline conditions in awake and halothane-anaesthetized rats, and after application of three types of stimuli which are likely to act...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(92)90711-h
更新日期：1992-05-29 00:00:00
abstract：:The suprachiasmatic nucleus (SCN) and the pineal body in 3 types of inherited hormone-deficient mice, the dw, lit and hyt mice were examined by morphological, morphometric and biochemical techniques. In the dw and lit mice the SCN was underdeveloped. In the ventral part of the SCN, where most of the retinal fibers app...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0165-3806(86)90279-8
更新日期：1986-05-01 00:00:00
abstract：:Chronic vitamin B12 (cobalamin) deficiency in the mammalian central nervous system causes degenerative damage, especially in the spinal cord. Previous studies have shown that cobalamin status alters spinal cord expression of epidermal growth factor (EGF) and its receptor in rats. Employing a mouse model of cobalamin-d...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2013.01.050
更新日期：2013-03-29 00:00:00
abstract：:To investigate the role of the amygdala in central regulation of pancreatic exocrine secretion, the effects of electrolytic lesions on pancreatic secretion were studied in rats. Small bilateral electrolytic lesions in amygdaloid body restricted to basolateral, medial and central nuclei were produced. Eight days after ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(85)90770-x
更新日期：1985-08-05 00:00:00
abstract：:Nuclear factor κB (NFκB) signaling plays ubiquitous roles in inflammation, immune response and neurogenesis. G protein-coupled receptor kinase 5 (GRK5) can protect neurons from degeneration. GRK5 also mediates tumor necrosis factor-α (TNFα)-induced NFκB signaling through the phosphorylation of IκBα. Here, we show that...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2015.02.041
更新日期：2015-05-22 00:00:00
abstract：:Rapid progress in our understanding of macrostructural abnormalities in autism spectrum disorders (ASD) has occurred in recent years. However, the relationship between the integrity of neural tissue and neural function has not been previously investigated. Single-voxel proton magnetic resonance spectroscopy and functi...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2007.04.081
更新日期：2007-08-08 00:00:00
abstract：:Neurons containing immunoreactivity to the endogenous lactose-binding lectin, RL-29, were examined in the L4 segment of the spinal cord of rats with an experimental neuropathy. The cells appeared by 5 days and were also present at 14 and 28 days postoperatively. All neurons were found in the dorsal horn ipsilateral to...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)90271-n
更新日期：1993-08-20 00:00:00
abstract：:Beta-amyloid (Abeta) peptides, the major component of senile plaques in brains of patients with Alzheimer's disease (AD), were found in the low pH organelles (i.e. endosome/lysosome) of cultured neuronal cells. Since acidic pH values have been shown to promote the self-assembly of Abetas, which seems to be a prerequis...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(00)03322-9
更新日期：2001-03-02 00:00:00
abstract：:Intracerebroventricular (ICV) streptozotocin (STZ) treated rat has been described as a suitable model for sporadic Alzheimer's disease (AD). Central application of STZ has demonstrated behavioral and neurochemical features that resembled those found in human AD. Chronic treatments with antioxidants, acetylcholinestera...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2011.09.056
更新日期：2011-12-02 00:00:00
abstract：:Rd mutant mice are visually blind but they maintain the ability of synchronising their circadian rhythms to the external light-dark cycles. We used immunocytochemical procedures to detect light-induced Fos expression in the rd mice retina. We found that Fos is expressed in the rd retina in an unattenuated pattern thro...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(99)01604-2
更新日期：1999-07-10 00:00:00
abstract：:Clusters of carotid body (glomus) cells cultured from a few days to 3 weeks, maintained their morphological characteristics during this period. The resting potential (Em) and input resistance (Ro) did not change for 2 weeks but both declined afterwards. The intracellular pH (pHi) of glomus cells, measured with glass m...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(91)90969-3
更新日期：1991-05-03 00:00:00
abstract：:In order to study the biosynthesis of myelin-associated proteins in Schwann cells, we have induced proliferation of cultured Schwann cells from neonatal rat sciatic nerve by transformation with Simian Virus 40 (SV40). Homogeneous transformed Schwann cell lines were established by single cell cloning. The transformed p...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(87)91324-2
更新日期：1987-06-23 00:00:00
abstract：:The neurochemical heterogeneity of the rat striatum was assessed in vivo by measuring subregional changes in extracellular dopamine and DOPAC by in vivo electrochemistry and microdialysis in response to amphetamine and the D2 antagonist, (-)-sulpiride. Both in vivo electrochemical and microdialysis experiments indicat...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(90)91256-g
更新日期：1990-01-08 00:00:00
abstract：:The exposure of cultured rat striatal neurons to L-DOPA caused marked cell death. The L-DOPA cytotoxicity was inhibited by the addition of Mg2+ to and by the removal of Ca2+ from the culture medium, and also by the application of tetrodotoxin. Moreover, prolonged application of L-DOPA increased the glutamate content i...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(97)00908-6
更新日期：1997-10-10 00:00:00
abstract：:The present paper examines the hypothesis that the long latency EMG activity produced by muscle stretch is the result of long loop reflex pathways involved in the control of limb stiffness. We recorded the cerebral responses and late EMG activity in agonist and antagonist muscles following sudden stretch of the wrist ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(92)91159-c
更新日期：1992-08-28 00:00:00
abstract：:Clozapine therapy has been associated with a high degree of urinary disturbances. The purpose of this study is to examine the effect of clozapine on urodynamic parameters and on the activity of the external urethral sphincter in anesthetized rats. Single cystometrograms (CMG) were performed on urethane-anesthetized fe...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(01)02352-6
更新日期：2001-05-18 00:00:00
