Abstract：
:The purpose of this paper is to investigate the involvement of various auditory localization mechanisms in the improvement of auditory spatial sensitivity in the case of partial visual deprivation. We compared sensitivity to binaural, monaural, and echo cues between normal-sighted and myopic subjects. In an auditory task, which depended solely upon binaural processing, myopic and normal-sighted subjects showed an almost equal localization performance. We also found that myopic subjects were no more disturbed than normal-sighted subjects when spectral shape cues were removed. On the other hand, near-sighted subjects exhibited better echolocation skills and a higher sensitivity to echo cues than normal-sighted subjects. We can therefore conclude that an improved auditory spatial sensitivity in myopic subjects may result from the increased use of echo information.
journal_name
Brain Resjournal_title
Brain researchauthors
Després O,Candas V,Dufour Adoi
10.1016/j.brainres.2005.01.101subject
Has Abstractpub_date
2005-04-11 00:00:00pages
56-65issue
1eissn
0006-8993issn
1872-6240pii
S0006-8993(05)00208-8journal_volume
1041pub_type
临床试验,杂志文章相关文献
BRAIN RESEARCH文献大全abstract：:This study examined the involvement of N-methyl-D-aspartate receptors (NMDARs) in experience-dependent synaptic plasticity. Rats chronically received an NMDA receptor antagonist (AP5) or saline (SAL) and were exposed to individual cages (IC) or environmental enrichment (EC). AP5 impaired measures of hippocampal-depend...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(00)02379-9
更新日期：2000-07-14 00:00:00
abstract：:We previously reported that reactive oxygen species (ROS) in paraventricular nucleus (PVN) modulated cardiac sympathetic afferent reflex (CSAR) and mediated the effect of angiotensin II (Ang II) in the PVN on the CSAR. In the present study, we investigated whether the NAD(P)H oxidase in the PVN was a key source of ROS...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2006.01.113
更新日期：2006-04-12 00:00:00
abstract：:The distribution of bFGF in mouse and rat retinas was established using an antibody generated against a rat specific bFGF sequence. The patterns established with this antibody were distinctly different in comparison to the immunostaining patterns using antibodies prepared against similar regions of bovine and human bF...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(92)91236-8
更新日期：1992-07-10 00:00:00
abstract：:The deposition of amyloid beta-peptide (Abeta) plays a crucial role in the pathogenesis of Alzheimer's disease (AD). Beta-site APP cleaving enzyme (BACE) is the rate-limiting enzyme in the Abeta formation. BACE mutations/polymorphisms may be associated with AD. We searched the BACE coding region mutations/polymorphism...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(02)03849-0
更新日期：2003-01-24 00:00:00
abstract：:To determine if aging in rats is associated with insensitivity of cerebral tissue to thyroid hormones (TH), the expression of a TH responsive protein or (THRP) in cerebral tissue was studied in male Fischer rats at 4, 12 and 24 months of age during euthyroid, hypothyroid and hyperthyroid states. The basal levels of TH...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(98)00144-9
更新日期：1998-05-18 00:00:00
abstract：:Increasing evidences show that hippocampal synaptic plasticity plays a crucial role in the pathogenesis of depression. The objective of this study was to determine whether electroacupuncture (EA) in the Wistar Kyoto (WKY) rat model of depression would exert antidepressant effects and whether this effect would be assoc...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2015.10.033
更新日期：2015-12-10 00:00:00
abstract：:Mice pretreated with the benzodiazepine antagonist, CGS 8216 (2.5, 10, or 40 mg/kg, i.p.) learned a T-maze discrimination to a fixed performance criterion more rapidly than vehicle-treated mice. In retention tests conducted one week later, the drug-treated groups had better first-trial recall and greater difficulty re...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(88)91223-1
更新日期：1988-09-13 00:00:00
abstract：:N2O antinociception was assessed in eight inbred and two outbred mouse strains. Results indicated the following order of responsiveness among the 10 strains: A/J (most sensitive), C57BL/6ByJ, C57BL/6J, BALB/cByJ, C3H/HeJ, Swiss-Webster, CXBK/ByJ, ICR, CBA/J and DBA/2J (least sensitive). These results demonstrate signi...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)91017-m
更新日期：1993-06-18 00:00:00
abstract：:Changes in GABA(A) receptor alpha(1) subunit gene expression occur in the globus pallidus and substantia nigra pars reticulata following lesions of the nigrostriatal tract. To determine whether these changes are translated at the protein level, we performed quantitative autoradiography with the alpha(1) selective liga...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(00)02081-3
更新日期：2000-04-17 00:00:00
abstract：:The objective of this study was to determine if a prefrontal somatosensory mismatch response (sMMR) could be recorded in response to deviations in duration of somatosensory stimuli. Intracranial somatosensory event-related potentials were recorded from temporal, parietal, and frontal lobe sites in 12 pediatric patient...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2009.10.072
更新日期：2010-01-15 00:00:00
abstract：:Cerebral cortex membranes from rats habituated to manipulations preceding decapitation (habituated rats) had 40% higher GABA binding than membranes from naive animals. Diazepam (5 X 10(-6) M), added to membranes from naive rats, increased GABA binding to the level of habituated rats, but failed to induce any further i...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(84)91114-4
更新日期：1984-07-02 00:00:00
abstract：:In barbiturate-anaesthetized spinal cats, antibody microprobes were used to examine immunoreactive substance P (irSP) release at sites within the spinal cord following cutaneous stimuli. A basal level of irSP release was detected in the region of the substantia gelatinosa of the lumbar spinal cord. No increase in this...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(88)90771-8
更新日期：1988-06-07 00:00:00
abstract：:Extracellular microelectrode recordings were made from a total of 868 neurons in the medullas of cats in regions known to contain high densities of respiratory-related neurons (solitary tract complex, nucleus ambiguus/retroambigualis, lateral tegmental field). Both the discharge patterns and the locations of units wer...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(84)90979-x
更新日期：1984-03-19 00:00:00
abstract：:The periodicity of the myelin sheath in glutaraldehyde carbohydrazide (GACH) embedded tissues from three 10-day-old and two 43-day-old mice was investigated with the electron microscope. The mean repeat period and number of repeats per fiber was measured in 31-89 fibers in the trapezoid bodies, olfactory tract and sci...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(76)90051-2
更新日期：1976-09-03 00:00:00
abstract：:We monitored biosynthetic activity of optic tract glia during regeneration of retinal ganglion cell axons in the goldfish and found that the greatest level of incorporated [3H]thymidine and [3H]leucine occurred in glia by 10-15 days after axotomy. During this period there was a marked increase in the number of oligode...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(85)90624-9
更新日期：1985-07-22 00:00:00
abstract：:The active and passive membrane properties of developing Purkinje neurons in control cultures and cultures chronically treated with 20 or 40 mM ethanol for 1 or 2 weeks were examined using whole-cell current-clamp techniques. The membrane properties were characterized by the features of the voltage responses evoked by...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(91)90707-3
更新日期：1991-08-30 00:00:00
abstract：:In previous studies we have tested the hypothesis that the termination of the period of sexual behavior in female guinea pigs results from the loss of progestin receptors from hypothalamic cell nuclei. We have shown that hormonal manipulations that delay heat termination also delay loss of hypothalamic nuclear progest...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(86)90320-3
更新日期：1986-05-14 00:00:00
abstract：:Previous research has demonstrated that cross-language activation is present even when proficient bilinguals perform a task only in one language. The present study investigated the time-course of cross-language activation during word production in a second language (L2) by using a picture-word interference paradigm wi...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2010.11.053
更新日期：2011-01-31 00:00:00
abstract：:We examined whether plasma epinephrine contributes to the increase in regional cerebral blood flow (rCBF) evoked by electrical stimulation of the dorsal medullary reticular formation (DMRF). Rats were anesthetized (alpha-chloralose, 30 mg/kg, s.c.), paralyzed and artificially ventilated. The DMRF was electrically stim...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(90)91203-s
更新日期：1990-01-01 00:00:00
abstract：:When a pair of stimuli separated by an appropriate interval is given to the right visceropleural connective of Aplysia californica the amplitude of the second EPSP elicited in cell R15 is usually smaller than the amplitude of the first EPSP. In the present paper we show that this phenomenon, synaptic depression, can b...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(76)90379-6
更新日期：1976-06-04 00:00:00
abstract：:The two human brain beta-galactosidases were solubilized and fractionated by Sephadex G-200 gel filtration, free from each other. Substrate specificities of the two enzymes were examined for galactosylceramide, lactosyl-[N-stearoyl]ceramide, lactosyl-[N-lignoceroyl]ceramide, galactosyl-N-acetylgalactosaminyl-[N-stearo...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(77)90298-0
更新日期：1977-02-18 00:00:00
abstract：:The interaction of glutamatergic and dopamine neurotransmission is thought to have relevance to both the pathophysiology and pharmacotherapy of schizophrenia. For example, subanesthetic doses of the N-methyl-D-aspartate receptor (NMDA-R) antagonist ketamine induce schizophrenia-like behavioral effects in humans and bo...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(01)01991-6
更新日期：2001-03-16 00:00:00
abstract：:The distribution of cerebellar [3H]flunitrazepam binding sites was studied autoradiographically in Purkinje cell degeneration (pcd/pcd), weaver (wv/wv), staggerer (sg/sg) and reeler (rl/rl) mutant mice. In the normal 78-day-old C57BL/6J mouse cerebellum, the highest concentration of [3H]flunitrazepam binding sites was...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(88)90920-1
更新日期：1988-03-15 00:00:00
abstract：:We recorded from the visual cortex of 4 groups of monocularly deprived kittens. Three groups were treated with intraventricular 6-hydroxydopamine (6-OHDA) at different times relative to monocular deprivation (MD). One group received only vehicle solution and MD. 6-OHDA caused the greatest decrease in plasticity in the...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0165-3806(87)90137-4
更新日期：1987-03-01 00:00:00
abstract：:Ion channels are integral membrane proteins that allow passive diffusion of ions across membranes. In neurons and in other excitable cells, the harmonious coordination between the numerous types of ion channels shape and propagate electrical signals. Increased accumulation of reactive oxidative species (ROS), and subs...
journal_title：Brain research
pub_type： 杂志文章,评审
doi：10.1016/j.brainres.2016.02.046
更新日期：2016-05-15 00:00:00
abstract：:The changes in the excitability of lumbosacral spinothalamic neurons produced by activating afferents in the trigeminal nerve using electrical or mechanical stimuli was investigated in cats anesthetized with alpha-chloralose. In most spinothalamic neurons, weak electrical stimuli or step indentations of the skin of th...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(79)90776-5
更新日期：1979-11-16 00:00:00
abstract：:The effects of duloxetine were examined on cloned Kv4.3 channels stably expressed in CHO cells using the whole-cell patch-clamp technique. Duloxetine decreased the peak amplitude of Kv4.3 currents with an acceleration of the decay rate of current inactivation in a concentration-dependent manner. The IC(50) values requ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2012.05.028
更新日期：2012-07-23 00:00:00
abstract：:Calcium currents were studied in morphologically identified pyramidal and stellate neurons acutely isolated from layer II/III of rat entorhinal cortex, using the whole-cell patch-clamp configuration. The peak amplitude of high-voltage activated current (HVA) measured at +10 mV was not different in both neuron populati...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(98)01234-7
更新日期：1999-01-23 00:00:00
abstract：:Factors underlying paired-pulse facilitation (PPF) were studied by intracellular and field recordings of CA1 neurons in the hippocampal slice in vitro, following stimulation of the Schaffer collaterals apical dendritic afferents. Similar magnitudes of PPF were found using the slopes or peaks of the excitatory postsyna...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(94)90209-7
更新日期：1994-07-04 00:00:00
abstract：:Electrophysiological studies using rats were performed to examine the influence of locus coeruleus (LC) on nucleus accumbens (Acc) neurons. Spike generation by hippocampal stimulation was inhibited by both LC conditioning stimulation and iontophoretic application of noradrenaline, but spikes elicited by stimulation of...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(85)90172-6
更新日期：1985-07-15 00:00:00
