Reduction of AMPA-selective glutamate receptor subunits in the entorhinal cortex of patients with Alzheimer's disease pathology: a biochemical study.

abstract：:Voltage-activated calcium channel currents were recorded from differentiated human neuroblastoma cells. SK-N-SH-SY5Y (SH-SY5Y) line, using patch-clamp techniques. Experimental solutions were designed to suppress sodium and potassium channel currents, and barium ions were used as the charge carrier. Two distinct types ...

journal_title：Brain research

authors： Reuveny E,Narahashi T

更新日期：1993-02-12 00:00:00

abstract：:The structurally related Aconitum alkaloids aconitine, lappaconitine, and 6-benzoylheteratisine inhibited the orthodromic and antidromic population spike in hippocampal CA1 area in a frequency-dependent manner. Aconitine (1 microM) completely suppressed epileptiform activity induced by omission of Mg2+ as well as norm...

journal_title：Brain research

authors： Ameri A,Gleitz J,Peters T

更新日期：1996-10-28 00:00:00

abstract：:Primate spinal cord tissue sections were sequentially incubated in serotonin (5-HT), substance P (SP) and methionine-enkephalin antisera and reacted immunocytochemically. The findings indicate that virtually all SP-like immunoreactivity coexists with 5-HT in the ventral horn, while an additional group of 5-HT terminal...

journal_title：Brain research

authors： Bowker RM

更新日期：1986-06-11 00:00:00

abstract：:Glycine is thought to be a major inhibitory neurotransmitter in the mammalian CNS. Two types of physiologically identified interneurons, Renshaw cells and Ia inhibitory interneurons, were intracellularly stained with horseradish peroxidase, and their axon terminals were studied at the electron microscopic level. Post-...

journal_title：Brain research

authors： Fyffe RE

更新日期：1991-04-26 00:00:00

abstract：:Among 235 histologically identified cells of the ventral lateral geniculate nucleus (LGV) in the cat, 66 responded antidromically to electrical stimulation of the pretectum (PT) and/or superior colliculus (SC): 22 projected to PT, 22 to SC and 22 to both sites. The LGV cells were innervated by optic tract fibers corre...

journal_title：Brain research

authors： Hada J,Yamagata Y,Hayashi Y

更新日期：1985-12-09 00:00:00

abstract：:Retrogradely labeled neurons are observed in the central nervous system of the toad after peripheral application of peroxidase to the anterior and posterior stumps of the VIIIth nerve. These efferent vestibular neurons are localized in the brainstem only ipsilaterally to the treated nerve; they are restricted within a...

journal_title：Brain research

authors： Pellegrini M,Ceccotti F,Magherini P

更新日期：1985-09-30 00:00:00

abstract：:The influence of emotion on cognition plays an important role in people's everyday life as well as in psychiatric and neurological disorders. The present study used fMRI to examine the neural correlates of cognitive-emotional interactions and its inter-individual differences. Twenty-one healthy males performed a 0-bac...

journal_title：Brain research

authors： Habel U,Koch K,Pauly K,Kellermann T,Reske M,Backes V,Seiferth NY,Stöcker T,Kircher T,Amunts K,Jon Shah N,Schneider F

更新日期：2007-06-04 00:00:00

abstract：:This study aimed to identify sites and mechanisms of long-term plasticity following lower limb muscle training. Two groups performing either a postural stability maintenance training (SMT) or a ballistic ankle strength training (BST) were compared to a non-training group. The hypothesis was that practicing of a self-i...

journal_title：Brain research

authors： Beck S,Taube W,Gruber M,Amtage F,Gollhofer A,Schubert M

更新日期：2007-11-07 00:00:00

abstract：:Endogenous hyperprolactinaemia was induced in intact male rats by transplantation of pituitaries under the kidney capsule. Five days later the utilization of noradrenaline (NA) and dopamine (DA) in individual brain nuclei and changes of plasma prolaction (PRL) were measured. Inhibition of catecholamine synthesis by al...

journal_title：Brain research

authors： Kovács GL,Drago F,Acsai L,Tihanyi A,Scapagnini U,Telegdy G

更新日期：1984-12-17 00:00:00

abstract：:The purpose of the present study was to examine the role of substrate availability in the regulation of the release and synthesis of serotonin by brain slices. Electrical field depolarization of the brain slices stimulated the synthesis and release of serotonin in the absence of changes in intracellular tryptophan con...

journal_title：Brain research

authors： Elks ML,Youngblood WW,Kizer JS

更新日期：1979-08-31 00:00:00

abstract：:The non-cholinergic excitatory potential elicited in neurons of the isolated inferior mesenteric ganglia was depressed by bath application of Met- or Leu-enkephalin and enhanced by naloxone or naltrexone. The membrane depolarization induced by exogenously applied putative transmitter substance P was not appreciably af...

journal_title：Brain research

authors： Jiang ZG,Simmons MA,Dun NJ

更新日期：1982-03-04 00:00:00

abstract：:The administration of alpha 2-adrenoreceptor antagonists SKF 64139 or SKF 72223 (TIQ derivatives) elicits an increase in striatal DOPA synthesis. The findings that the enhanced DOPA synthesis is reversed by pretreatment of the animals with clonidine or with the D beta H inhibitor FLA-63 suggest that action of the TIQ ...

journal_title：Brain research

authors： Rabey JM,Passeltiner P,Bystritsky A,Engel J,Goldstein M

更新日期：1981-12-28 00:00:00

abstract：:The expression of the calcium-binding protein calretinin (CR) in the chick cochlear nucleus, nucleus magnocellularis (NM), was examined after unilateral cochlea removal in hatchlings and 3-week-old birds. Following survival times of 3, 6 or 12 h or 1, 3 or 7 days, CR mRNA was localized by in situ hybridization using a...

journal_title：Brain research

authors： Stack KE,Code RA

更新日期：2000-08-04 00:00:00

abstract：:To address the question of whether fine myelinated and unmyelinated primary afferent fibers contribute to the mechanism of presynaptic inhibition in the spinal cord, we studied dorsal root-evoked dorsal root potentials (DR-DRPs) using a newly developed longitudinal spinal cord slice preparations in the adult rat. Sing...

journal_title：Brain research

authors： Shimizu T,Yoshimura M,Baba H,Shimoji K,Higashi H

更新日期：1995-09-11 00:00:00

abstract：:We examined the effect of the peripheral application of glutamate and capsaicin to the temporomandibular joint (TMJ) in influencing the activation and central sensitization of TMJ-responsive nociceptive neurons in the trigeminal subnucleus caudalis/upper cervical cord (Vc/UCC). The activity of single neurons activated...

journal_title：Brain research

authors： Lam DK,Sessle BJ,Hu JW

更新日期：2009-02-09 00:00:00

abstract：:A comparison was made of the effects of left and right cerebral decortication on cytotoxic activity of natural killer and natural cytotoxic lymphocytes in the mouse. Natural killer cytotoxic activity was significantly reduced after right decortication, whereas left decortication led to a less pronounced, though still ...

journal_title：Brain research

authors： Belluardo N,Mudò G,Cella S,Bindoni M

更新日期：1990-08-06 00:00:00

abstract：:The relationship between the dorsal raphe neurons projecting to the caudate-putamen and those projecting to the substantia nigra was investigated using a fluorescent retrograde double labeling technique in the rat. The majority of the dorsal raphe neurons projecting to the substantia nigra were found to project also t...

journal_title：Brain research

authors： van der Kooy D,Hattori T

更新日期：1980-03-17 00:00:00

abstract：:The adaptation to hypoxia and hypercapnia requires the activation of several anatomical structures along the neuraxis. In this study, using Fos immunoreactivity, we sought to map neuronal populations involved in chemoreflex networks activated during the responses to moderate hypoxia (O(2) 11%), and hypercapnia (CO(2) ...

journal_title：Brain research

authors： Berquin P,Bodineau L,Gros F,Larnicol N

更新日期：2000-02-28 00:00:00

abstract：:Neurotrophic factors (NTFs), beside regulating neuronal survival in the central and peripheral nervous system, are also involved in the modulation of neuronal function in the adult animal. Both brain-derived neurotrophic factor (BDNF) and glial cell-derived neurotrophic factor (GDNF) levels are altered in pathological...

journal_title：Brain research

authors： Ciobanu C,Reid G,Babes A

更新日期：2009-08-11 00:00:00

abstract：:Morphological alterations occurring in Schwann cells of unmyelinated fibers (unmyelinated Schwann cells) were investigated in the sciatic nerve of the twicher mouse, a murine model of human globoid cell leukodystrophy. After postnatal day 10, the number of Schwann cell-axon units gradually increased and the number of ...

journal_title：Brain research

authors： Tanaka K,Nagara H,Kobayashi T,Goto I,Suzuki K

更新日期：1989-11-27 00:00:00

abstract：:Trigeminal hyperalgesia frequently appears in diabetic neuralgia altering the transmission of orofacial sensory information. This study was designed to explore the effects of trigeminal hyperalgesia in streptozotocin-induced diabetes monitoring the expression of nitric oxide synthase in the trigeminal ganglion cells. ...

journal_title：Brain research

authors： Rodella L,Rezzani R,Corsetti G,Bianchi R

更新日期：2000-05-19 00:00:00

abstract：:Because considerable work has implicated the basal ganglia in oral-ingestive behavior, an assessment was made of the effects of trigeminal stimuli upon entopeduncular single units. Units wre recorded extracellularly in awake, paralyzed and locally anesthetized cats. The effects of two types of sensory input were teste...

journal_title：Brain research

authors： Lidsky TI,Robinson JH,Denaro FJ,Weinhold PM

更新日期：1978-02-10 00:00:00

abstract：:In anaesthetized cats, effects of iontophoretic application of angiotensin II were studied in the nuclei of the tractus solitarius. Specifically, its effects were tested on single respiratory neurones, having rhythmic activity related temporally with the phrenic nerve discharge, and on presumed reflex interneurones, w...

journal_title：Brain research

authors： Sessle BJ,Henry JL

更新日期：1987-03-24 00:00:00

abstract：:In recent decades, an increasing number of neuroimaging studies utilizing magnetic resonance imaging (MRI) have explored the differential effects of postherpetic neuralgia (PHN) on brain structure and function. We systematically reviewed and integrated the findings from relevant neuroimaging studies in PHN patients. A...

journal_title：Brain research

authors： Tang Y,Wang M,Zheng T,Xiao Y,Wang S,Han F,Chen G

更新日期：2021-02-01 00:00:00

abstract：:Partial sciatic nerve ligation in mice caused a marked and persistent decrease in the latency of paw withdrawal from a thermal stimulus only on the ipsilateral side. This thermal hyperalgesia was abolished by repeated intrathecal pretreatment with a specific antibody to brain-derived neurotrophic factor (BDNF), but no...

journal_title：Brain research

authors： Yajima Y,Narita M,Narita M,Matsumoto N,Suzuki T

更新日期：2002-12-27 00:00:00

abstract：:Human neuroblastoma SH-SY5Y cells were used to study the effects of transforming growth factor beta1 (TGF-beta1) and bone morphogenetic protein 2 (BMP-2) on neuronal differentiation and acquisition of a catecholaminergic phenotype. SH-SY5Y cells express the intracellular factors activated through the receptors of the ...

journal_title：Brain research

authors： Gómez-Santos C,Ambrosio S,Ventura F,Ferrer I,Reiriz J

更新日期：2002-12-20 00:00:00

abstract：:The effect of lactic acidosis on calcium influx, accumulation and efflux was studied in primary cultures of neonatal cortical rat astrocytes. Treatment of cultures with 20 mM sodium lactate, pH 6.0, for 10-60 min resulted in a 35% reduction of 45Ca2+ influx. The decrease in calcium influx was pH dependent because a si...

journal_title：Brain research

authors： Neary JT,Fu Q,Bender AS,Norenberg MD

更新日期：1993-02-26 00:00:00

abstract：:In most vertebrates and several insects, melatonin (N-acetyl-5-methoxytryptamine) is synthesized enzymatically from serotonin (5-hydroxytryptamine) by the sequential action of arylalkylamine N-acetyltransferase (NAT) and hydroxyindole-O-methyltransferase (HIOMT). In the freshwater planarian Dugesia japonica, which bel...

journal_title：Brain research

authors： Itoh MT,Shinozawa T,Sumi Y

更新日期：1999-05-29 00:00:00

abstract：:The malformative cortical lesions in the cerebral cortex that are characteristic of focal cortical dysplasia type IIb (FCDIIb) and tuberous sclerosis complex (TSC) are well-recognized causes of chronic intractable epilepsy in children. Increasing evidence suggests that extracellular matrix molecules play important rol...

journal_title：Brain research

authors： Li S,Yu S,Zhang C,Shu H,Liu S,An N,Yang M,Yin Q,Yang H

更新日期：2012-05-09 00:00:00

abstract：:Glioblastoma is the most aggressive form of gliomas and is associated with short survival. Recent advancements in molecular genetics resulted in the identification of glioma genomic, epigenomic and transcriptomic hallmarks, and multidimensional data allowed clustering of glioblastomas into molecular subtypes. Parallel...

journal_title：Brain research

authors： Nagy A,Eder K,Selak MA,Kalman B

更新日期：2015-01-21 00:00:00