Abstract:
:Glycine is thought to be a major inhibitory neurotransmitter in the mammalian CNS. Two types of physiologically identified interneurons, Renshaw cells and Ia inhibitory interneurons, were intracellularly stained with horseradish peroxidase, and their axon terminals were studied at the electron microscopic level. Post-embedding immunogold procedures were used to reveal the presence of glycine-like immunoreactivity. The synaptic terminals of both types of interneuron were significantly enriched with glycine-like immunoreactivity, providing support for the idea that glycine is a mediator of synaptic transmission in the recurrent and reciprocal inhibitory pathways to motoneurons.
journal_name
Brain Resjournal_title
Brain researchauthors
Fyffe REdoi
10.1016/0006-8993(91)90590-rsubject
Has Abstractpub_date
1991-04-26 00:00:00pages
175-9issue
1eissn
0006-8993issn
1872-6240pii
0006-8993(91)90590-Rjournal_volume
547pub_type
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