Abstract：
:Patients undergoing dental treatment employ different attentional strategies. In order to investigate associated neuronal correlates, we exposed 20 women suffering from dental phobia and 20 non-anxious women to disorder-related and unrelated pictures. They were asked to either direct their attention to a foreground stimulus in the image (distraction), to classify the content, or to judge whether the picture elicited fear of pain. The patients rated the majority of dental pictures as pain-relevant (84%) in contrast to the control group (12%). Observed group differences were restricted to the pain condition with enhanced orbitofrontal cortex (OFC) activation displayed by the patients. For the controls, OFC and amygdala activity were positively correlated with self-reported dental anxiety during attention to pain. Across both groups, pain focusing provoked increased amygdala recruitment. As the OFC and amygdala are central for the evaluation of threat signals, the mere thinking about the possible pain relevance of stimuli seems to be dysfunctional.
journal_name
Brain Resjournal_title
Brain researchauthors
Scharmüller W,Ubel S,Leutgeb V,Schoengassner F,Wabnegger A,Schienle Adoi
10.1016/j.brainres.2014.04.017subject
Has Abstractpub_date
2014-05-30 00:00:00pages
69-76eissn
0006-8993issn
1872-6240pii
S0006-8993(14)00515-0journal_volume
1566pub_type
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