Enhanced visuomotor associative learning following stimulation of alpha 2A-adrenoceptors in the ventral prefrontal cortex in monkeys.

abstract：:Neurotensin (NT) is a neuropeptide neurotransmitter in the central nervous system. It has been implicated in the therapeutic and in the adverse effects of neuroleptics. Activity of NT in brain can only be shown by direct injection of the peptide into that organ. However, we have developed a novel analog of NT(8-13), N...

journal_title：Brain research

authors： Cusack B,Boules M,Tyler BM,Fauq A,McCormick DJ,Richelson E

更新日期：2000-02-21 00:00:00

abstract：:Neurointermediate lobes of rats comprise elements which, when excited in vitro, bring about an inhibition of the release of melanocyte stimulating hormone (MSH). Superfusion of neurointermediate lobes of intact donor rats with medium containing 45 mM K+ induced a stimulation of the release of oxytocin, arginine-vasopr...

journal_title：Brain research

authors： Tilders FJ,van der Woude HA,Swaab DF,Mulder AH

更新日期：1979-08-10 00:00:00

abstract：:Temporo-nasal asymmetry in visual responses has been observed in many behavioural studies. These observations have typically been attributed to the anatomical asymmetry of fibres projecting to the Superior Colliculus (SC), even though this attribution is debated. The present study investigates temporo-nasal asymmetry ...

journal_title：Brain research

authors： Bertini C,Leo F,Làdavas E

更新日期：2008-11-25 00:00:00

abstract：:Nerve growth activities in rat sciatic nerves were assayed by recording the neuritic outgrowth from chick embryonic ganglia cultured in collagen gels beside nerve fragments for two days. Living nerve explants released activity that resembled nerve growth factor (NGF) in its effect on sympathetic ganglia and that was a...

journal_title：Brain research

authors： Richardson PM,Ebendal T

更新日期：1982-08-19 00:00:00

abstract：:Soluble guanylyl cyclase is a heterodimeric (alpha, beta) enzyme generating the second messenger, cGMP, upon activation by the gaseous messenger, nitric oxide. The occurrence and distribution of alpha 1-, alpha 2-, beta 1- and beta 2-subunits were investigated in trigeminal and dorsal root ganglia on the mRNA and the ...

journal_title：Brain research

authors： Kummer W,Behrends S,Schwarzlmüller T,Fischer A,Koesling D

更新日期：1996-05-20 00:00:00

abstract：:Brain extracellular matrix (ECM) is highly degraded after cerebral ischemia. The perlecan c-terminal fragment LG3 is generated at increased levels by proteolytic processing as long as 3 days after ischemia. It has previously been shown that oxygen-glucose deprivation (OGD), reperfusion and interleukin-1 α (IL-1α) stim...

journal_title：Brain research

authors： Saini MG,Bix GJ

更新日期：2012-02-15 00:00:00

abstract：:Microtubule-associated protein 1B (MAP1B) is expressed at high levels during development of the nervous system and is localized primarily in neurons while specific phosphorylated isoforms of MAP1B are localized exclusively in growing axons. The levels of MAP1B are down regulated in most regions of the adult CNS, but r...

journal_title：Brain research

authors： Ma D,Chow S,Obrocka M,Connors T,Fischer I

更新日期：1999-03-27 00:00:00

abstract：:The recent indications of specialized lateralization of cardiovascular regulation within the right and left posterior insular cortex of the rat, suggest the possibility of transcallosal connectivity between these regions. This has not been previously demonstrated using physiological techniques. Extracellular neural re...

journal_title：Brain research

authors： Zhang Z,Oppenheimer SM

更新日期：2000-04-28 00:00:00

abstract：:Distribution of somatostatin (SS) immunoreactivity was observed in the preoptic-anterior hypothalamus (PO-AH) of the female rat brain. Six specific rabbit antibodies A (SS-14), B (SS-28), C (SS-28 complete), D (SS 14 and SS-28 both), E (SS preprohormone) and F (GHRH) were used for immunostaining using Avidin-Biotin Co...

journal_title：Brain research

authors： Bhatnagar M

更新日期：2001-05-11 00:00:00

abstract：:Lateral ventricular injection of antibodies to dynorphin A(1-13) was previously shown to elevate lateral hypothalamic stimulation frequency threshold for eliciting feeding behavior. The antibodies utilized in that study cross-react completely with dynorphin A(1-17) and, to a lesser extent, dynorphin A(1-8). In the pre...

journal_title：Brain research

authors： Carr KD,Bak TH

更新日期：1990-01-22 00:00:00

abstract：:alpha-Motoneurons innervating the triceps surae and short plantar muscles were stained intracellularly with horseradish peroxidase (HRP) in 0-44-day-old kittens and adult cats. The terminal arborizations of the recurrent axon collaterals in the spinal cord were studied in the light microscope (LM). The short plantar m...

journal_title：Brain research

authors： Cullheim S,Ulfhak B

更新日期：1985-01-01 00:00:00

abstract：:The neural connections from the ventral pallidum (VP) through the mediodorsal nucleus of the thalamus (MD) to the medial prefrontal cortex (MPC) were investigated. Extracellular recordings were made from 219 neurons in the medial and lateral portions of the MD and the VP and the MPC were stimulated. The most frequent ...

journal_title：Brain research

authors： Vives F,Mogenson GJ

更新日期：1985-10-07 00:00:00

abstract：:Our previous studies have indicated that oxygen radicals, produced during reoxygenation following short-term arterial hypoxia, lead to sustained suppression of cerebral arteriolar responses to N-methyl-D-aspartate (NMDA). However, whether arteriolar dilator responses to NMDA are reduced during arterial hypoxia has nev...

journal_title：Brain research

authors： Bari F,Thore CR,Louis TM,Busija DW

更新日期：1998-01-12 00:00:00

abstract：:Zinc and other cations were iontophoretically applied to neurones in the frontoparietal cortex of urethane-anaesthetised rats and their effect on the activity of these cells was examined. Slow and often prolonged increases in firing rate occurred in 45.2% of neurones after zinc application and 72.7% after barium. Calc...

journal_title：Brain research

authors： Wright DM

更新日期：1984-10-08 00:00:00

abstract：:This report deals with a comparison of total and regional cerebral blood flow with red cell velocity in the microcirculation of the ecto- and suprasylvian areas of the cerebral cortex of the cat and their response to changes in systemic blood pressure. Total and regional blood flows were measured during a steady-state...

journal_title：Brain research

authors： Chang BL,Santillan G,Bing RJ

更新日期：1984-08-06 00:00:00

abstract：:Lavender belongs to the family Labiatae and has a variety of cosmetic uses as well as therapeutic purposes in herbal medicine. The present study was conducted to evaluate the protective effect of lavender oil against brain edema and its possible mechanisms in an experimental model of stroke. Under Laser-Doppler Flowme...

journal_title：Brain research

authors： Vakili A,Sharifat S,Akhavan MM,Bandegi AR

更新日期：2014-02-22 00:00:00

abstract：:Locomotor stepping elicited by lateral hypothalamic stimulation in the anesthetized rat is blocked by lesions in the anterior ventromedial midbrain. This study determined in acute experiments whether the dorsal midbrain regions implicated in locomotion were also part of the necessary pathway. Rats were anesthetized wi...

journal_title：Brain research

authors： Sinnamon HM,Stopford CK

更新日期：1987-01-27 00:00:00

abstract：:Fast axonal transport and neuronal protein synthesis was studied in the isolated nervous system of Aplysia californica. The abdominal ganglion with attached pleural-abdominal connectives (PAC) was removed and the ganglion pulse-labelled with [35S]methionine for 30 min in vitro. The axon containing connectives were lig...

journal_title：Brain research

authors： Drake PF,Oblinger MM,Lasek RJ

更新日期：1985-04-15 00:00:00

abstract：:The associative learning functions of the central nervous system of Limax maximus have been established with behavioral experiments on intact animals (Sahley et al., J. comp. Physiol., 144 (1981) 1) and physiological experiments on the isolated CNS (Culligan and Gelperin, Brain Research, 266 (1983) 319). We now report...

journal_title：Brain research

authors： Gelperin A,Culligan N

更新日期：1984-06-25 00:00:00

abstract：:The therapeutic use of neurotrophic factors to treat neurodegenerative disorders, including Alzheimer's disease, is considered feasible. Magnolol and honokiol, constituents of the Magnolia plant, are small organic compounds with neurotrophic activity. We investigated whether magnolol and honokiol can prevent age-relat...

journal_title：Brain research

authors： Matsui N,Takahashi K,Takeichi M,Kuroshita T,Noguchi K,Yamazaki K,Tagashira H,Tsutsui K,Okada H,Kido Y,Yasui Y,Fukuishi N,Fukuyama Y,Akagi M

更新日期：2009-12-11 00:00:00

abstract：:Thyroid hormone effects on brain somatostatin-like immunoreactivity (SRIF-LI) were studied in an in vitro model system. Serum was removed from the nutrient culture medium of fetal day-18 rat cerebral cortex cells maintained in primary, long-term, dispersed monolayer culture. Chronic administration of either T3 or T4 i...

journal_title：Brain research

authors： Peterfreund RA,Sawchenko PE,Vale W

更新日期：1985-03-04 00:00:00

abstract：:Depending on experimental conditions, chronic cocaine exposure can induce an increase in binding to the dopamine transporter (DAT). One possible mechanism for the cocaine-induced-upregulation in DAT binding sites is through stimulation of presynaptic D2 receptors by excess synaptic dopamine. To test this hypothesis, t...

journal_title：Brain research

authors： Little KY,Gorebig J,Carroll FI,Mapili J,Meador-Woodruff JH

更新日期：1996-12-02 00:00:00

abstract：:The effect of valproic acid (VPA) on synaptic transmission was investigated at the frog neuromuscular junction using electrophysiological methods. The drug caused a dose-dependent decrease in the quantal content of the endplate potential (EPP) and a significant reduction in the input resistance of the postjunctional m...

journal_title：Brain research

authors： Alkadhi KA,Banks FW

更新日期：1984-07-23 00:00:00

abstract：:An extensive exploration of the discriminating properties of olfactory receptors cells has been conducted in our laboratory through the statistical processing of single cell responses recorded in the frog's olfactory epithelium. Similarities between odorant stimulating properties could be demonstrated by comparing the...

journal_title：Brain research

authors： Sicard G,Holley A

更新日期：1984-02-06 00:00:00

abstract：:In vitro quantitative autoradiography of high-affinity [3H]desmethylimipramine (DMI) binding sites was performed on 24 human brains postmortem. Highest densities of binding sites were found in portions of the amygdala, the granular layer of the dentate gyrus, the pyramidal layer of CA4. Next, in descending order were ...

journal_title：Brain research

authors： Gross-Isseroff R,Israeli M,Biegon A

更新日期：1988-07-19 00:00:00

abstract：:This study has examined the retinal synapses of the cat superior colliculus using electron microscope autoradiography and morphometric techniques. The depth of each retinal synapse was measured using a computer-based EM plotter. The area, perimeter, and synapse contact density of selected synapses were calculated usin...

journal_title：Brain research

authors： Mize RR

更新日期：1983-06-20 00:00:00

abstract：:We showed previously, using in vitro microdialysis, that the activation of the soluble guanylate cyclase (sGC)/cyclic GMP pathway was the underlying mechanism of the extracellular Ca(2+)-dependent effects of exogenous NO on dopamine (DA) secretion from PC12 cells. In this study, the co-infusion of the sGC inhibitor 1H...

journal_title：Brain research

authors： Rocchitta G,Migheli R,Mura MP,Esposito G,Desole MS,Miele E,Miele M,Serra PA

更新日期：2004-10-15 00:00:00

abstract：:Numerous studies have suggested that nitric oxide (NO) in the nucleus tractus solitarii (NTS) participates in modulating cardiovascular function. Nitric oxide synthase (NOS), the enzyme responsible for synthesis of NO, exists in 3 isoforms: endothelial NOS (eNOS), neuronal NOS (nNOS), and inducible NOS (iNOS). Althoug...

journal_title：Brain research

authors： Lin LH,Taktakishvili O,Talman WT

更新日期：2007-09-26 00:00:00

abstract：:Two pathways that have been shown to mediate cerebral ischemic damage are the MEK/ERK cascade and the pro-apoptotic deltaPKC pathway. We investigated the relationship between these pathways in a rat model of focal ischemia by observing and modifying the activation state of each pathway. The ERK1/2 inhibitor, U0126, in...

journal_title：Brain research

authors： Castañeda D,Zhao H,Mochly-Rosen D,Steinberg GK

更新日期：2009-01-28 00:00:00

abstract：:The compound m-chlorophenylpiperazine (m-CPP) is used clinically to manipulate serotonergic function, though its precise mechanisms of actions are not well understood. m-CPP alters synaptic transmission and neuronal function in vertebrates by non-selective agonistic actions on 5-HT(1) and 5-HT(2) receptors. In this st...

journal_title：Brain research

authors： Sparks GM,Brailoiu E,Brailoiu GC,Dun NJ,Tabor J,Cooper RL

更新日期：2003-04-18 00:00:00