Nitric oxide synthase is concentrated at the skeletal muscle endplate.

Abstract:

:NO performs a wide array of cell signaling functions. Neuronal NO synthase (nNOS) immunoreactivity and nicotinamide adenine dinucleotide phosphate diaphorase (NDP) activity, a marker of nNOS, were concentrated at adult rat neuromuscular junctions and persisted in denervated muscle indicating the localization of the enzyme to the postsynaptic surface. The concentration of nNOS at the muscle endplate suggests NO could serve as a messenger pre- and postsynapticly.

journal_name

Brain Res

journal_title

Brain research

authors

Kusner LL,Kaminski HJ

doi

10.1016/0006-8993(96)00675-0

subject

Has Abstract

pub_date

1996-08-19 00:00:00

pages

238-42

issue

1-2

eissn

0006-8993

issn

1872-6240

pii

0006-8993(96)00675-0

journal_volume

730

pub_type

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