Actin filament organization within dendrites and dendritic spines during development.

Abstract:

:The myosin S-1 subfragment was used to label actin filaments in the developing rat brain. The results show actin filaments present throughout the dendritic region with highest concentrations within growth cones and regions of spine development. Between 6 and 25 days postnatal, spines became more complex and actin filaments within them increased in number and formed a complex network. The observed organization of actin supports the hypothesis that actin has a role in the protrusion of spines from the dendrite during development.

journal_name

Brain Res

journal_title

Brain research

authors

Markham JA,Fifková E

doi

10.1016/0165-3806(86)90253-1

subject

Has Abstract

pub_date

1986-06-01 00:00:00

pages

263-9

issue

1-2

eissn

0006-8993

issn

1872-6240

journal_volume

392

pub_type

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