Cilostazol inhibits leukocyte-endothelial cell interactions in murine microvessels after transient bilateral common carotid artery occlusion.

abstract：:The immunohistochemical studies on a peroxisomal enzyme, catalase, were done on brains from human fetuses to adults. The catalase-positive neurons appeared in the basal ganglia, thalamus and cerebellum at 27-28 weeks of gestation, and in the frontal cortex at 35 weeks. They then increased in number with gestational ag...

journal_title：Brain research

authors： Houdou S,Kuruta H,Hasegawa M,Konomi H,Takashima S,Suzuki Y,Hashimoto T

更新日期：1991-08-16 00:00:00

abstract：:Responsiveness of single inferotemporal (IT) neurons to a tone as a start or warning signal in each test trial was investigated in monkeys performing visual discrimination of 4 patterns. It was found that the same IT neurons were responsive to both auditory signal and visual discriminanda with different response chara...

journal_title：Brain research

authors： Iwai E,Aihara T,Hikosaka K

更新日期：1987-04-28 00:00:00

abstract：:The intra-axonal transport of horseradish peroxidase (HRP) has been used to trace the nodose ganglion and brain stem projections of a physiologically distinct nerve - the aortic depressor nerve - following electrophysiological identification. Tetramethyl benzidine (TMB) has been used as the substrate for demonstrating...

journal_title：Brain research

authors： Kalia M,Welles RV

更新日期：1980-04-21 00:00:00

abstract：:An extensive exploration of the discriminating properties of olfactory receptors cells has been conducted in our laboratory through the statistical processing of single cell responses recorded in the frog's olfactory epithelium. Similarities between odorant stimulating properties could be demonstrated by comparing the...

journal_title：Brain research

authors： Sicard G,Holley A

更新日期：1984-02-06 00:00:00

abstract：:We examined the effect of gangliosides on Schwann cell cultures isolated from neonatal rat sciatic nerves. Addition of gangliosides (GM1, GM3, and ganglioside mixture) at concentrations between 0.25 and 2 mg/ml significantly diminished both the baseline rate of proliferation of the Schwann cells and their response to ...

journal_title：Brain research

authors： Sobue G,Taki T,Yasuda T,Mitsuma T

更新日期：1988-12-06 00:00:00

abstract：:The melanocortin (MC)4 receptor is important for food intake and weight homeostasis as it mediates the orexigenic and anorexigenic effects of the MCs. OLETF (Otsuka-Long-Evans-Tokushima-Fatty) rats are a selective inbred strain of polygenic variant rats which overeat and develop obesity with elevated leptin levels. We...

journal_title：Brain research

authors： Lindblom J,Schiöth HB,Watanobe H,Suda T,Wikberg JE,Bergström L

更新日期：2000-01-03 00:00:00

abstract：:This study investigated the relationship between central cholinergic neurons and insulin secretion in bilateral adrenalectomized fed rats. Neostigmine (a cholinesterase inhibitor, 5 x 10(-8) mol) administered into the third cerebral ventricle produced significant increases in hepatic venous plasma insulin and glucose ...

journal_title：Brain research

authors： Gotoh M,Iguchi A,Yatomi A,Uemura K,Miura H,Futenma A,Kato K,Sakamoto N

更新日期：1989-07-24 00:00:00

abstract：:Glutamate is the main excitatory neurotransmitter in the central nervous system. This amino acid mediates learning and memory processes acting through ionotropic and metabotropic receptor binding. Metabotropic glutamate receptors (mGluRs) are G protein-coupled receptors that stimulate phospholipase C (PLC) or inhibit ...

journal_title：Brain research

authors： Iglesias I,Castillo CA,León D,Ruíz MA,Albasanz JL,Martín M

更新日期：2007-06-11 00:00:00

abstract：:Hydrocephalus with aqueduct stenosis was a consistent feature in mice which received a single intraperitoneal injection of 6-aminonicotinamide (6-AN) on day 5 postnatal. Chronological investigation revealed that 6-AN-treated mice had aqueductal obstruction with edematously swollen ependymal cells and spongy changes in...

journal_title：Brain research

authors： Aikawa H,Suzuki K

更新日期：1985-10-01 00:00:00

abstract：:Prefrontal impairments have been hypothesized to be most strongly associated with the cognitive and emotional dysfunction in depression. Recently, white matter microstructural abnormalities in prefrontal lobe have been reported in elderly patients with major depressive disorder (MDD) using diffusion tensor imaging (DT...

journal_title：Brain research

authors： Li L,Ma N,Li Z,Tan L,Liu J,Gong G,Shu N,He Z,Jiang T,Xu L

更新日期：2007-09-07 00:00:00

abstract：:A common feature of many neurodegenerative disorders is an abundance of activated glial cells (astrocytes and microglia). In Alzheimer's disease (AD), activated astrocytes are in close apposition to and surrounding the amyloid plaques. The mechanisms by which the astrocytes become activated in AD and the consequences ...

journal_title：Brain research

authors： Hu J,Akama KT,Krafft GA,Chromy BA,Van Eldik LJ

更新日期：1998-03-02 00:00:00

abstract：:A large body of evidence indicates that both the altered cytokines that mediate the immune-inflammatory process and abnormal gray matter are associated with schizophrenia. Whether peripheral cytokines are related to cerebral structural abnormality remains unclear. Therefore, we aimed to investigate the association of ...

journal_title：Brain research

authors： Wu D,Lv P,Li F,Zhang W,Fu G,Dai J,Hu N,Liu J,Xiao Y,Li S,Shah C,Tao B,Zhao Y,Gong Q,Lui S

更新日期：2019-12-01 00:00:00

abstract：:Many of the behavioral consequences of dopamine system activation are thought to be mediated by substantia nigra pars reticulata output pathways. Extracellular, single unit recording studies were conducted to determine how i.v. administration of the dopamine agonist, apomorphine, affects the activity of these pars ret...

journal_title：Brain research

authors： Waszczak BL,Lee EK,Ferraro T,Hare TA,Walters JR

更新日期：1984-07-23 00:00:00

abstract：:Several studies, using electrical stimulation of parts of the hypothalamus, have shown, that different parts of the hypothalamus yield different behavioural responses upon stimulation. In order to differentiate between stimulation of neuronal cell bodies and passing fibres and to investigate the role of GABA in hypoth...

journal_title：Brain research

authors： Roeling TA,Kruk MR,Schuurmans R,Veening JG

更新日期：1993-06-25 00:00:00

abstract：:The distribution of calretinin containing neurons examined by in situ hybridization mapping was compared with that obtained by immunocytochemistry in the brain of octopus. Results revealed a close correspondence between the two types of investigations. Western blot analysis disclosed a 29 kDa protein immunostained wit...

journal_title：Brain research

authors： Altobelli GG,Cimini V

更新日期：2007-02-09 00:00:00

abstract：:In the present study we have examined the effects of changes in potassium and calcium concentration on the early adaptation of the slowly adapting stretch receptor of the crayfish using intracellular recordings including the potential clamp technique. This was because previous studies had suggested that the early adap...

journal_title：Brain research

authors： Ottoson D,Swerup C

更新日期：1985-06-10 00:00:00

abstract：:This report deals with the effect of substance P (SP) and capsaicin on blood pressure and heart rate after administration into different sites of the nucleus tractus solitarii (NTS) of urethane-anesthetized rats. Microinjection of SP at 6 different coordinates throughout the NTS showed 3 sites where SP administration ...

journal_title：Brain research

authors： Lukovic L,de Jong W,de Wied D

更新日期：1987-10-06 00:00:00

abstract：:Slow negative potentials, evoked by stimulation of the lumbar dorsal roots, have been demonstrated in the dorsal horn of an isolated, hemisected spinal cord preparation from golden hamsters. Paired stimuli revealed a period of partial suppression of this slow potential persisting for up to 2 s following the conditioni...

journal_title：Brain research

authors： Bagust J,Forsythe ID,Kerkut GA,Loots JM

更新日期：1982-02-04 00:00:00

abstract：:Ethanol caused a concentration-dependent loss of PC12 cells over a 24 h interval, accompanied by an increase in intracellular calcium. The specific alpha7 nicotinic receptor partial agonist DMXB attenuated both of these ethanol-induced actions at a concentration (3 microM) found previously to protect against apoptotic...

journal_title：Brain research

authors： Li Y,King MA,Grimes J,Smith N,de Fiebre CM,Meyer EM

更新日期：1999-01-16 00:00:00

abstract：:Intracisternal injections of hypocretin-1 (hcrt-1) have been shown to elicit sympathoexciatory responses. However, the location of central sites that may mediate these cardiovascular effects have not been clearly elucidated. This study was done in male Wistar rats to investigate the effects of microinjections of hcrt-...

journal_title：Brain research

authors： Ciriello J,Li Z,de Oliveira CV

更新日期：2003-11-21 00:00:00

abstract：:The effects of estrus and prolonged estradiol benzoate (EB) treatment on estrogen receptor-like immunoreactivity (ER-LI) were studied in the female Brazilian opossum (monodelphis domestica) brain. In general, both estrus animals and EB treated animals had reduced ER-LI in specific brain regions when compared to ovarie...

journal_title：Brain research

authors： Pearson PL,Ross LR,Jacobson CD

更新日期：1993-07-16 00:00:00

abstract：BACKGROUND:Empathizing is a specific component of social cognition. Empathizing is also specifically impaired in autism spectrum condition (ASC). These are two dimensions, measurable using the Empathy Quotient (EQ) and the Autism Spectrum Quotient (AQ). ASC also involves strong systemizing, a dimension measured using t...

journal_title：Brain research

authors： Wheelwright S,Baron-Cohen S,Goldenfeld N,Delaney J,Fine D,Smith R,Weil L,Wakabayashi A

更新日期：2006-03-24 00:00:00

abstract：:In degenerating frog sciatic nerves an in situ perfusion technique was used to measure the permeability coefficient-surface area product (PA) of endoneurial capillaries to [14C]sucrose, and the endoneurial vascular space (V). Both PA and V started to increase after the 3rd day of degeneration. The increase in PA peake...

journal_title：Brain research

authors： Weerasuriya A

更新日期：1988-03-29 00:00:00

abstract：:Freeze-fracture examination of nodes of Ranvier from adult rat optic nerve demonstrates the presence of astrocytic processes at the majority of nodes of Ranvier. Astrocytic processes often run along the entire length of the nodal gap, although they do not necessarily encircle the entire nodal circumference. The E- and...

journal_title：Brain research

authors： Waxman SG,Black JA

更新日期：1984-08-06 00:00:00

abstract：:In a single 10-s training trial, hatchling chicks were conditioned to suppress their spontaneous peck response to a small spherical target by coating it with an aversive liquid. A 24-h test trial employing a dry target demonstrated a robust memory for the training manifested in passive avoidance behavior. Leupeptin, a...

journal_title：Brain research

authors： Davis JL,Pico RM

更新日期：1987-03-17 00:00:00

abstract：:Single cell recordings were made from neurons in the lateral tegmental field of the medulla (LTFM) during electrical stimulation of the hypothalamic defense area (HDA) of the rabbit. Fifty-four cells were inhibited by HDA stimulation; 23 of these cells received barosensory input. Twenty-two LTFM cells showed an increa...

journal_title：Brain research

authors： Winters RW,McCabe PM,Green EJ,Duan YF,Schneiderman N

更新日期：1991-08-30 00:00:00

abstract：:Protease-activated receptors (PARs), G-protein-coupled receptors, are widely expressed in various tissues, where they participate in physiological and pathological processes, such as hemostasis, proliferation, tissue repair, and inflammation. Recently, we found that PARs were upregulated in the rat retina following op...

journal_title：Brain research

authors： Luo W,Wang Y,Reiser G

更新日期：2005-06-21 00:00:00

abstract：:We tested the hypothesis that intravenous infusion of human marrow stromal cells (hMSC) with a nitric oxide donor, (Z)-1-[N-(2-aminoethyl)-N-(2-ammonioethyl) aminio] diazen-1-ium-1,2-diolate (DETA/NONOate), enhances angiogenesis, neurogenesis and neurological functional recovery after stroke in rats compared to indivi...

journal_title：Brain research

authors： Chen J,Li Y,Zhang R,Katakowski M,Gautam SC,Xu Y,Lu M,Zhang Z,Chopp M

更新日期：2004-04-16 00:00:00

abstract：:Traumatic brain injury (TBI) causes impairments of both motor and spatial memory performances. Research is only beginning to reveal the biochemical mechanism(s) underlying these deficits. It has been postulated that reactive oxygen species such as the superoxide and hydroxyl radicals, as well as the peroxynitrite anio...

journal_title：Brain research

authors： Long DA,Ghosh K,Moore AN,Dixon CE,Dash PK

更新日期：1996-04-22 00:00:00

abstract：:Glucocorticoids (GCs) predispose hippocampal neurons to damage during metabolic stressors. One component of hippocampal GC-endangerment may be changes in neuronal defenses against oxidative challenge. Previous experiments showed a decrease in basal levels of copper/zinc superoxide dismutase (Cu/Zn SOD) and glutathione...

journal_title：Brain research

authors： McIntosh LJ,Cortopassi KM,Sapolsky RM

更新日期：1998-04-27 00:00:00