Differential down-regulation of estrogen receptor-like immunoreactivity by estradiol in the female Brazilian opossum brain.

Abstract:

:The effects of estrus and prolonged estradiol benzoate (EB) treatment on estrogen receptor-like immunoreactivity (ER-LI) were studied in the female Brazilian opossum (monodelphis domestica) brain. In general, both estrus animals and EB treated animals had reduced ER-LI in specific brain regions when compared to ovariectomized controls. These results support a down-regulatory role for estrogen in relation to its receptor in the brain, and indicate that ER-LI is differentially regulated in the Monodelphis forebrain.

journal_name

Brain Res

journal_title

Brain research

authors

Pearson PL,Ross LR,Jacobson CD

doi

10.1016/0006-8993(93)90632-w

subject

Has Abstract

pub_date

1993-07-16 00:00:00

pages

171-5

issue

1

eissn

0006-8993

issn

1872-6240

pii

0006-8993(93)90632-W

journal_volume

617

pub_type

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