Reticularis thalami afferents to the ventrobasal complex of the rat thalamus: an electron microscope study.

abstract：:Alzheimer's disease is a common age associated neurodegenerative disorder associated with an elevated risk of seizures that may be fundamentally connected to cognitive dysfunction. We used 4-9month-old mice of the APP/PS1 mouse model of Alzheimer's disease to study the presence of epileptiform-like discharges and to e...

journal_title：Brain research

authors： Reyes-Marin KE,Nuñez A

更新日期：2017-12-15 00:00:00

abstract：:The motivational effects of exclusively peripheral or central opiate receptor blockade were studied using place conditioning. Place aversions were observed with intraventricular (i.c.v.) methylnaloxone (MN) in both naive (200-1000 ng) and morphine-dependent rats (50-500 ng). Subcutaneous MN (0.03-10 mg/kg) was ineffec...

journal_title：Brain research

authors： Hand TH,Koob GF,Stinus L,Le Moal M

更新日期：1988-12-06 00:00:00

abstract：:A hypothalamic oxytocinergic-descending pathway that reaches the dorsal horn of the spinal cord has been well documented and recently related to states of pain and analgesia. In order to study the action of the neuropeptide oxytocin (OT) on pain-related responses, we compared dorsal horn neuronal responses to electric...

journal_title：Brain research

authors： Condés-Lara M,Maie IA,Dickenson AH

更新日期：2005-05-31 00:00:00

abstract：:Opioid-binding cell adhesion molecule (OBCAM) is the member of the IgLON family, a subgroup of the immunoglobulin superfamily. In the present study, the functions and dynamics of OBCAM were investigated in hippocampal neurons in vitro. Western blotting revealed that OBCAM expression was low at early stages of culture ...

journal_title：Brain research

authors： Yamada M,Hashimoto T,Hayashi N,Higuchi M,Murakami A,Nakashima T,Maekawa S,Miyata S

更新日期：2007-08-24 00:00:00

abstract：:Lateral ventricular injection of antibodies to dynorphin A(1-13) was previously shown to elevate lateral hypothalamic stimulation frequency threshold for eliciting feeding behavior. The antibodies utilized in that study cross-react completely with dynorphin A(1-17) and, to a lesser extent, dynorphin A(1-8). In the pre...

journal_title：Brain research

authors： Carr KD,Bak TH

更新日期：1990-01-22 00:00:00

abstract：:Transient global cerebral ischemia (TGCI) occurs during acute severe hypotension depriving the brain of oxygen and glucose for a short period of time. During reperfusion, several mechanisms can induce secondary neuronal damage, including the increased production of reactive oxygen species (ROS). Hydrogen gas-enriched ...

journal_title：Brain research

authors： Hugyecz M,Mracskó E,Hertelendy P,Farkas E,Domoki F,Bari F

更新日期：2011-08-02 00:00:00

abstract：:Functionally activated sites usually have multiple specificities where coactivation is induced by inputs with different informational content. Using typical voxel-based functional mapping (univariate analysis), it is possible to show the presence of coactivation; however, it is not possible to distinguish whether coac...

journal_title：Brain research

authors： Sung YW,Choi SH,Hong SJ,Choi US,Cho JH,Ogawa S

更新日期：2010-12-17 00:00:00

abstract：:Brevetoxins (PbTx) are potent allosteric enhancers of voltage-gated sodium channel (VGSC) function and are associated with periodic "red tide" blooms. These neurotoxins produce neuronal injury and death in cerebellar granule cells (CGC) following acute exposure. In murine neocortical neurons, brevetoxin induces Ca(2+)...

journal_title：Brain research

authors： Dravid SM,Baden DG,Murray TF

更新日期：2005-01-07 00:00:00

abstract：:The activity of single dopaminergic (DA) neurons (total n = 77) in the midbrain of awake, unrestrained rats was examined. The firing rates and patterns of ventral tegmental area (A10) cells (n = 39) were similar to those of identified DA neurons in anesthetized and paralyzed rats. Unit activity was briefly stimulated ...

journal_title：Brain research

authors： Freeman AS,Bunney BS

更新日期：1987-03-03 00:00:00

abstract：:Distribution of adult T cell leukemia derived factor (ADF/TRX), a human thioredoxin homologue, was studied by immunohistochemistry in gerbil brain during reperfusion after transient cerebral ischemia. In control brains, immunoreactivity was observed widely in the central nervous system, including the ependyma, tanycyt...

journal_title：Brain research

authors： Tomimoto H,Akiguchi I,Wakita H,Kimura J,Hori K,Yodoi J

更新日期：1993-10-15 00:00:00

abstract：:The L-isomer of beta-N-methylamino-L-alanine (BMAA), present in free form in seed of Cycas circinalis, elicits in spinal cord cultures a pattern of acute postsynaptic neuronal vacuolation comparable to that induced by beta-N-oxalylamino-L-alanine (BOAA), an excitotoxic amino acid of greater potency isolated from seed ...

journal_title：Brain research

authors： Nunn PB,Seelig M,Zagoren JC,Spencer PS

更新日期：1987-05-05 00:00:00

abstract：:Oxygen therapy (OT) with hyperbaric oxygen (HBO) or normobaric hyperoxia (NBO) improves the oxygenation of penumbral tissue in experimental ischemic stroke. However, whether this results in the improvement of energy metabolism is unclear. We investigated the effect of both OTs on tissue acidosis and on ATP production....

journal_title：Brain research

authors： Sun L,Strelow H,Mies G,Veltkamp R

更新日期：2011-09-30 00:00:00

abstract：:Pretreatment with scopolamine, 3 mg/kg, prevented the acquisition of a passive avoidance task in rats. These amnesic effects of scopolamine could largely be overcome by treatment with 100 mg/kg of the nootropic drug piracetam. In order to identify the brain structures involved, the effects of these drugs on regional e...

journal_title：Brain research

authors： Piercey MF,Vogelsang GD,Franklin SR,Tang AH

更新日期：1987-10-20 00:00:00

abstract：:The present study investigated the antidepressant potential of curcumin in olfactory bulbectomy and forced swimming test models of depression in male albino rats under chronic treatment. The experimental animals were divided into four groups, and curcumin was administered for 45 days. Our results showed that the curcu...

journal_title：Brain research

authors： Chang XR,Wang L,Li J,Wu DS

更新日期：2016-07-01 00:00:00

abstract：:This study evaluates the neuroprotective effects of geranylgeranylacetone (GGA), which is known as an antiulcer agent and more recently as a heat-shock and other neuroprotective protein inducer, on secondary degeneration after spinal cord injury in rats. Crush injuries were produced at the T8 level using an extradural...

journal_title：Brain research

authors： Fujiki M,Furukawa Y,Kobayashi H,Abe T,Ishii K,Uchida S,Kamida T

更新日期：2005-08-16 00:00:00

abstract：:Practical utilization of in vivo electrochemistry for brain studies has been impeded by difficulties with specificity and quantitative measurements. Studies in brain slices combined with similar data from intact animals have provided important new information on the nature of the electrochemical studies. Using the enz...

journal_title：Brain research

authors： Schenk JO,Miller E,Rice ME,Adams RN

更新日期：1983-10-24 00:00:00

abstract：:The aim of the present report is to investigate in detail morphometric changes of axon terminals of area 17 of adult cat induced by methylmercury intoxication. Six adult male cats (Felix catus), with 12 h day-light cycle and ad libitum water and food regimen, received a single dose of MeHgCl (6.4 mg/kg) dissolved in m...

journal_title：Brain research

authors： de Oliveira RB,Gomes Leal W,Picanço-Diniz DL,Torres Neto JB,Lins N,Malm O,Picanço-Diniz CW

更新日期：2008-12-09 00:00:00

abstract：:A sample of 302 neurons in rat hindlimb granular cortex was studied between 2 and 3 weeks after transection and ligation of the sciatic nerve. These neurons were compared to a control sample obtained from normal rats under similar experimental conditions. After sciatic nerve transection the proportion of neurons drive...

journal_title：Brain research

authors： Dykes RW,Lamour Y

更新日期：1988-05-24 00:00:00

abstract：:Numerous studies with PC12 cells have suggested that the mitogen-activated protein (MAP) kinase pathway might play a major role in the neuronal differentiation that is induced by nerve growth factor (NGF). Cells of the PC12D subline extend neurites within several hours in response to NGF in the presence of inhibitors ...

journal_title：Brain research

authors： Sano M,Kitajima S

更新日期：1998-03-02 00:00:00

abstract：:To test the hypothesis that presence of metalloproteases (MMPs), their inhibitors (TIMPs) and their substrate laminin-5 differs between the ischemic core and the surrounding tissue, we examined the impact of middle cerebral artery occlusion/reperfusion (MCA:O/R) on these molecules in different regions of the infarct. ...

journal_title：Brain research

authors： Wagner S,Nagel S,Kluge B,Schwab S,Heiland S,Koziol J,Gardner H,Hacke W

更新日期：2003-09-12 00:00:00

abstract：:The effects of acute ethanol exposure of chick spinal cord neurons were studied in tissue culture, using whole-cell voltage-clamp techniques. Results indicate that ethanol produces a persistent increase in the sensitivity of spinal neurons to GABA and glycine, with no change in input resistance or resting membrane pot...

journal_title：Brain research

authors： Celentano JJ,Gibbs TT,Farb DH

更新日期：1988-07-12 00:00:00

abstract：:In the present study, the role of medial septal receptors in behaviour-induced increase in acetylcholine (ACh) release in hippocampus was investigated using dual-probe microdialysis in combination with a simple behavioural procedure. gamma-Aminobutyric acid (GABA) and glutamate receptor agonists and antagonists were a...

journal_title：Brain research

authors： Moor E,Schirm E,Jacsó J,Westerink BH

更新日期：1998-04-06 00:00:00

abstract：:Recent studies have demonstrated the neuroprotective properties of the novel imidazoquinoline benzodiazepine receptor partial agonist, PNU-101017, in the gerbil forebrain ischemia model. The compound effectively reduces delayed post-ischemic (5 min bilateral carotid occlusion) hippocampal CA1 neuronal degeneration eve...

journal_title：Brain research

authors： Hall ED,Fleck TJ,Oostveen JA

更新日期：1998-07-06 00:00:00

abstract：:The interpeduncular nucleus (IPN) was stimulated electrically while single-cell activity was recorded in the nucleus raphe magnus (NRM) of rats under pentobarbital anesthesia. Two classes of NRM cell were examined, those inhibited (off-cells) and those excited (on-cells) by noxious mechanical skin stimulation. Off-cel...

journal_title：Brain research

authors： Hentall ID,Budhrani VM

更新日期：1990-07-09 00:00:00

abstract：:The stress-related neurohormone, corticotropin-releasing factor (CRF), also acts as a neurotransmitter to activate the brain noradrenergic nucleus, locus coeruleus (LC). Previous electrophysiological findings demonstrating that tonic CRF secretion in the LC is increased in adrenalectomized rats suggest that activity o...

journal_title：Brain research

authors： Lechner SM,Valentino RJ

更新日期：1999-01-16 00:00:00

abstract：:In alert cats, extracellular spikes of neurons in the medial pontine tegmentum were recorded simultaneously with whole nerve discharges of the abducens and medial rectus nerves during horizontal vestibular nystagmus. Nystagmus-related neurons were classified by their firing patterns in relation to the abrupt cessation...

journal_title：Brain research

authors： Curthoys IS,Nakao S,Markham CH

更新日期：1981-10-05 00:00:00

abstract：:The nature of the delayed blood-brain barrier (BBB) opening that occurs in rats subjected to forebrain ischemia by the technique of two-vessel (carotid) occlusion plus hypovolemic hypotension (2VO ischemia) was probed by examining the simultaneous, trans-barrier movement of two hydrophilic, normally poorly permeative ...

journal_title：Brain research

authors： Preston E,Foster DO

更新日期：1997-06-27 00:00:00

abstract：:The immunohistochemical studies on a peroxisomal enzyme, catalase, were done on brains from human fetuses to adults. The catalase-positive neurons appeared in the basal ganglia, thalamus and cerebellum at 27-28 weeks of gestation, and in the frontal cortex at 35 weeks. They then increased in number with gestational ag...

journal_title：Brain research

authors： Houdou S,Kuruta H,Hasegawa M,Konomi H,Takashima S,Suzuki Y,Hashimoto T

更新日期：1991-08-16 00:00:00

abstract：:Spontaneous interictal spikes (SISs) were recorded in the hippocampus in freely behaving rats following hippocampal stimulations that resulted in afterdischarges (ADs). Hippocampal SISs were detected after an average of 5 (range 2-10) daily ADs. The rate of SISs typically increased minutes after a tetanus, and then de...

journal_title：Brain research

authors： Leung LW

更新日期：1990-04-16 00:00:00

abstract：:Post traumatic stress disorder (PTSD) is characterised by hyperarousal, anxiety and amnesic symptoms. Deficits in explicit memory recall have been causally related to volume reductions of the hippocampus and prefrontal cortex. While stress-related glucocorticoid secretion appears involved in this apparent atrophy, the...

journal_title：Brain research

authors： Harvey BH,Naciti C,Brand L,Stein DJ

更新日期：2003-09-05 00:00:00