Abstract：
:The immunohistochemical studies on a peroxisomal enzyme, catalase, were done on brains from human fetuses to adults. The catalase-positive neurons appeared in the basal ganglia, thalamus and cerebellum at 27-28 weeks of gestation, and in the frontal cortex at 35 weeks. They then increased in number with gestational age. The extent of immunopositive staining increased with enlargement of perikaryonal size. However, the extent gradually decreased with postnatal age. On the other hand, catalase-positive glia appeared in the deep white matter at 31-32 weeks of gestation, their appearance shifting from the deep to the superficial white matter with increasing age. These results suggest that peroxisomes are closely related to neuronal growth and myelinogenesis in the human brain during development.
journal_name
Brain Resjournal_title
Brain researchauthors
Houdou S,Kuruta H,Hasegawa M,Konomi H,Takashima S,Suzuki Y,Hashimoto Tdoi
10.1016/0006-8993(91)90314-lsubject
Has Abstractpub_date
1991-08-16 00:00:00pages
267-70issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(91)90314-Ljournal_volume
556pub_type
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