Electrophysiological evidence for hypothalamic defense area input to cells in the lateral tegmental field of the medulla of rabbits.

abstract：:The suitability of (3H)DPCPX (8-cyclopentyl-1,3-dipropylxanthine), a xanthine derivative, as an vivo probe for labelling adenosine A1 receptors was studied in rats. [3H]DPCPX (nM) penetrated largely into the brain (0.8% of the injected dose per gram of brain tissue 5 min after injection). Brain concentrations stayed a...

journal_title：Brain research

authors： Bisserbe JC,Pascal O,Deckert J,Mazière B

更新日期：1992-12-18 00:00:00

abstract：:Converging evidence suggests that compromised motor abilities in hemiparetic cerebral palsy are not solely due to impairments in motor execution, but are also related to deficits in action planning. The present study had two aims. First, we compared grip planning in a sequential task between participants with left-sid...

journal_title：Brain research

authors： Crajé C,van der Kamp J,Steenbergen B

更新日期：2009-03-19 00:00:00

abstract：:The rat mutant dystonic displays an autosomal recessive neurological disease characterized by slow, twisting movements of the limbs and trunk. Rats displaying clinical signs also show a decreased behavioral response to the dopaminergic blocker, haloperidol. Investigation of the development of the cataleptic response t...

journal_title：Brain research

authors： McKeon TW,Lorden JF,Oltmans GA,Beales M,Walkley SU

更新日期：1984-08-06 00:00:00

abstract：:Nicergoline, a drug used for the treatment of Alzheimer's disease and other types of dementia, was tested for its ability to protect neurons against beta-amyloid toxicity. Pure cultures of rat cortical neurons were challenged with a toxic fragment of beta-amyloid peptide (betaAP(25-35)) and toxicity was assessed after...

journal_title：Brain research

authors： Caraci F,Chisari M,Frasca G,Canonico PL,Battaglia A,Calafiore M,Battaglia G,Bosco P,Nicoletti F,Copani A,Sortino MA

更新日期：2005-06-14 00:00:00

abstract：:Global forebrain ischemia of 5-min duration results in delayed neuronal death (DND) of CA1 neurons in the gerbil hippocampus. DND can be prevented by a preconditioning sublethal ischemic stimulus (2. 5 min), a phenomenon, known as ischemic tolerance induction. Striking evidence exists for the involvement of regulatory...

journal_title：Brain research

authors： Kapinya K,Penzel R,Sommer C,Kiessling M

更新日期：2000-07-28 00:00:00

abstract：:We elucidated how Alzheimer-type pathologies of amyloid beta-protein (Abeta) and tau spatiotemporally emerge in brains of nontransgenic nonhuman primate, cynomolgus monkey, in the present study. To examine the accumulation of deposited Abeta, phosphorylated tau accumulation, intracellular tau accumulation, and neurofi...

journal_title：Brain research

authors： Oikawa N,Kimura N,Yanagisawa K

更新日期：2010-02-22 00:00:00

abstract：:Zinc-enriched (ZEN) neurons are distributed widely throughout the brain and spinal cord. Synaptic vesicle zinc in these neurons is thought to function as a neuromodulator upon its release into the synaptic cleft. Consistent with this possibility, zinc or zinc chelators can alter spatial learning, working memory, and n...

journal_title：Brain research

authors： Cole TB,Martyanova A,Palmiter RD

更新日期：2001-02-09 00:00:00

abstract：:The retinohypothalamic tract, a monosynaptic retinal projection to the suprachiasmatic nucleus (SCN), is the path by which light entrains the circadian system to the external photoperiod. Serotonergic neurons in the mesencephalic median raphe nucleus (MnR) also give rise to a major SCN afferent projection. The present...

journal_title：Brain research

authors： Muscat L,Tischler RC,Morin LP

更新日期：2005-05-17 00:00:00

abstract：:Rats with electrodes in either the posterior medial forebrain bundle (MFB), the anterior MFB, the medial prefrontal cortex, or the locus coeruleus self-stimulated during a 45 min period following the injection of [14C]2-deoxyglucose. They were then sacrificed and their brains prepared for autoradiography. The autoradi...

journal_title：Brain research

authors： Yadin E,Guarini V,Gallistel CR

更新日期：1983-04-25 00:00:00

abstract：:Quantitative in situ hybridization histochemistry was used to compare the effects of AMPH administration on mRNAs coding for zif/268, a member of the zinc finger family of immediate early genes, and the opioid peptides, preprodynorphin (PPD) and preproenkephalin (PPE), in rat striatum after 3 dosing schedules: (1) acu...

journal_title：Brain research

authors： Wang JQ,McGinty JF

更新日期：1995-03-06 00:00:00

abstract：:The aim of the present report is to investigate in detail morphometric changes of axon terminals of area 17 of adult cat induced by methylmercury intoxication. Six adult male cats (Felix catus), with 12 h day-light cycle and ad libitum water and food regimen, received a single dose of MeHgCl (6.4 mg/kg) dissolved in m...

journal_title：Brain research

authors： de Oliveira RB,Gomes Leal W,Picanço-Diniz DL,Torres Neto JB,Lins N,Malm O,Picanço-Diniz CW

更新日期：2008-12-09 00:00:00

abstract：:Responses of pyramidal neurons to ionophoretic kainate, quisqualate and N-methyl aspartate were studied in a submerged rat piriform cortex slice as a function of Ca2+ and Mg2+ concentrations. The results suggest that the channel activated by kainate is unusually influenced by Ca2+, excitotoxicity is Ca2+-dependent and...

journal_title：Brain research

authors： Hori N,Ffrench-Mullen JM,Carpenter DO

更新日期：1985-12-09 00:00:00

abstract：:Adequate grip force modulation is critical to manual dexterity and often impaired in hemiparetic stroke patients. Previous studies in hemiparetic patients suggest that aspects of grip force control may be differently affected by the lesion. We developed a visuomotor power grip force-tracking task allowing quantificati...

journal_title：Brain research

authors： Lindberg PG,Roche N,Robertson J,Roby-Brami A,Bussel B,Maier MA

更新日期：2012-05-03 00:00:00

abstract：:Using an immunocytochemical technique we have analyzed changes in substance P, somatostatin, calcitonin gene-related peptide, and galanin immunoreactivity pattern in the rat dorsal root ganglia. After 7 days of adrenalectomy, sham operated rats were compared with adrenalectomized animals either receiving a daily intra...

journal_title：Brain research

authors： Coveñas R,DeLeón M,Chadi G,Cintra A,Gustafsson JA,Narvaez JA,Fuxe K

更新日期：1994-03-21 00:00:00

abstract：:Severed medial giant axons in crayfish can be rejoined in vitro with polyethylene glycol (PEG) to produce axoplasmic continuity and through transmission of action potentials. Severed axon-like processes of a mammalian neuroblastoma/glioma cell line seem to be rejoined to the cell body using PEG in tissue culture. Our ...

journal_title：Brain research

authors： Bittner GD,Ballinger ML,Raymond MA

更新日期：1986-03-05 00:00:00

abstract：:A monospecific antibody against tyrosine hydroxylase (TH), purified from a transplantable rat pheochromocytoma, was produced in rabbits. Immunohistochemical techniques were employed in order to determine if a relationship exists between the subcellular distribution of TH and the level of activation of the enzyme in th...

journal_title：Brain research

authors： Stephens JK,Masserano JM,Vulliet PR,Weiner N,Nakane PK

更新日期：1981-03-30 00:00:00

abstract：:This study investigated the long-lasting effects of chronic ethanol consumption on the distribution of Schaffer collateral-commissural (SCH/COM) afferents within stratum radiatum of rat hippocampal CA1. Experimental animals were fed an ethanol-containing liquid diet for 20 weeks but were withdrawn from the special die...

journal_title：Brain research

authors： Abraham WC,Manis PB,Hunter BE,Zornetzer SF,Walker DW

更新日期：1982-04-08 00:00:00

abstract：:The role of glial cells in nitric oxide production in the cerebellum of conscious rats was investigated with a glial selective metabolic inhibitor, fluorocitrate. The levels of nitric oxide metabolites (nitrite plus nitrate) in the dialysate following in vivo microdialysis progressively increased to more than 2-fold t...

journal_title：Brain research

authors： Yamada K,Senzaki K,Komori Y,Nikai T,Sugihara H,Nabeshima T

更新日期：1997-07-11 00:00:00

abstract：:Transplantation of fetal substantia nigra into the brain can alleviate some of the manifestations of animal models of Parkinson's disease. The purpose of the present experiment was to determine the optimal embryonic donor age for solid tissue substantia nigra grafts. Rats with unilateral substantia nigra lesions were ...

journal_title：Brain research

authors： Simonds GR,Freed WJ

更新日期：1990-10-15 00:00:00

abstract：:Activation of the immune system produces psychological and physiological effects, which resemble the characteristics of depression. The present study was designed to investigate further, in rats, the similarity between the behavioral effects of immune activation and a model of depression in animals. Reduction in the p...

journal_title：Brain research

authors： Yirmiya R

更新日期：1996-03-04 00:00:00

abstract：:We cloned the genes for the mouse homologue of the neuromedin B receptor (NMB-R) and the bombesin receptor subtype 3 (BRS-3). Both receptor genes consist of three exons with well-conserved intron-exon borders. Although the NMB-R gene spans more than 10 kb, the BRS-3 gene spans only about 4 kb. Comparison of the mouse ...

journal_title：Brain research

authors： Ohki-Hamazaki H,Wada E,Matsui K,Wada K

更新日期：1997-07-11 00:00:00

abstract：:The window method of radiolabeled protein analysis was used to study the transport kinetics of axonally transported cytomatrix proteins as they move through segments of mouse optic axons. Three slow component b (SCb) proteins--actin, a 30 kDa protein, and clathrin--were radiolabeled in the eye and were followed for up...

journal_title：Brain research

authors： Paggi P,Lasek RJ,Katz MJ

更新日期：1990-05-28 00:00:00

abstract：:Electrophysiological studies using rats were performed to examine the influence of locus coeruleus (LC) on nucleus accumbens (Acc) neurons. Spike generation by hippocampal stimulation was inhibited by both LC conditioning stimulation and iontophoretic application of noradrenaline, but spikes elicited by stimulation of...

journal_title：Brain research

authors： Unemoto H,Sasa M,Takaori S

更新日期：1985-07-15 00:00:00

abstract：:Cell bodies and dendrites of neurones in the thalamic reticular nucleus projecting to the dorsal lateral geniculate nucleus in adult albino rats, were labelled by retrograde transport of horseradish peroxidase (HRP). In the same animals the terminals of cortico-reticular axons were made identifiable by ipsilateral vis...

journal_title：Brain research

authors： Ohara PT,Lieberman AR

更新日期：1981-02-23 00:00:00

abstract：:Since several different pathways are involved in cerebral ischemia/reperfusion injury, combination therapy rather than monotherapy may be required for efficient neuroprotection. In this study, we examined the protective effects of an apoptosis inhibitor Gly(14)-humanin (HNG) and a necroptosis inhibitor necrostatin-1 (...

journal_title：Brain research

authors： Xu X,Chua KW,Chua CC,Liu CF,Hamdy RC,Chua BH

更新日期：2010-10-08 00:00:00

abstract：:Glucocorticoids (GC) provide neuroprotection and early recovery after spinal cord injury (SCI). While several mechanisms were proposed to account for these effects, limited information exists regarding GC actions in sensory areas of the spinal cord. Presently, we studied the time course of Fos expression, and reduced ...

journal_title：Brain research

authors： González S,Labombarda F,Gonzalez Deniselle MC,Saravia FE,Roig P,De Nicola AF

更新日期：2001-09-07 00:00:00

abstract：:In the present study, we used an immunocytochemical technique at the electron microscopic level to determine if there are changes in the glutamate and GABA neurotransmitter content of the hippocampus of genetic absence epilepsy rats from Strasbourg (GAERS). We also investigated if there was mossy fiber reorganization....

journal_title：Brain research

authors： Sirvanci S,Meshul CK,Onat F,San T

更新日期：2003-10-24 00:00:00

abstract：:Histone proteins from purified nuclei of neonatal and adult mouse retinas were analyzed and compared utilizing SDS-polyacrylamide gel electrophoresis. Identical procedures were applied to examine the histones extracted from the brains of the same animals. In the newborn and mature retina and brain, 8 histone fractions...

journal_title：Brain research

authors： Perkins PS,Young RW

更新日期：1987-06-01 00:00:00

abstract：:Understanding the structural and functional development of neurons in networks has a high impact to estimate the potentials for restorative therapies. Neurons derived from the human NT2 cell line (hNT) formed networks with a clustered neuritic architecture in vitro, whereas primary dissociated embryonic rat cortical n...

journal_title：Brain research

authors： Görtz P,Fleischer W,Rosenbaum C,Otto F,Siebler M

更新日期：2004-08-20 00:00:00

abstract：:The present study aimed to determine whether the observation of different grasps of the same object elicits automatic imitation of the kinematics of those grasps and this process influences the estimation of intrinsic target properties. In experiments 1 and 2, participants reached and grasped differently sized spheres...

journal_title：Brain research

authors： Gianelli C,Dalla Volta R,Barbieri F,Gentilucci M

更新日期：2008-07-07 00:00:00