Functional analysis of the role of the median raphe as a regulator of hamster circadian system sensitivity to light.

abstract：:In a previous study we reported significant elevations of TRH in neocortex, hippocampus and combined amygdala/pyriform cortex in rats 48 h after the last of a series of stage 5 kindled seizures. In the present study, to determine whether the increases in TRH were proportional to the intensity of the convulsions, and t...

journal_title：Brain research

authors： Meyerhoff JL,Bates VE,Kubek MJ

更新日期：1990-08-13 00:00:00

abstract：:We report the localization of angiotensin-converting enzyme (kininase II, EC 3.4.15.1) in discrete nuclei and areas of the rat brain by a quantitative autoradiographic technique using image processing coupled to computerized microdensitometry, after incubation of brain sections with the specific converting enzyme inhi...

journal_title：Brain research

authors： Correa FM,Plunkett LM,Saavedra JM

更新日期：1986-06-11 00:00:00

abstract：:Intravenous administration of lipopolysaccharide (LPS) (0.9 mg/kg) has been shown to induce ischemic tolerance in spontaneously hypertensive rats (SHR). TNF-alpha is believed to play a crucial role in preconditioning as its inhibition with TNF-alpha-binding protein abolished tolerance. Our recent studies (Liu et al., ...

journal_title：Brain research

authors： Zimmermann C,Ginis I,Furuya K,Klimanis D,Ruetzler C,Spatz M,Hallenbeck JM

更新日期：2001-03-23 00:00:00

abstract：:A large body of evidence indicates that both the altered cytokines that mediate the immune-inflammatory process and abnormal gray matter are associated with schizophrenia. Whether peripheral cytokines are related to cerebral structural abnormality remains unclear. Therefore, we aimed to investigate the association of ...

journal_title：Brain research

authors： Wu D,Lv P,Li F,Zhang W,Fu G,Dai J,Hu N,Liu J,Xiao Y,Li S,Shah C,Tao B,Zhao Y,Gong Q,Lui S

更新日期：2019-12-01 00:00:00

abstract：:The sexually dimorphic nucleus of the preoptic area (SDN-POA) is the most striking structure displaying a morphological sex difference in the rat brain. A potentially homologous nucleus has been identified in the human hypothalamus. The objective of the present study was to pursue the putative homology of the rat and ...

journal_title：Brain research

authors： Gao B,Moore RY

更新日期：1996-12-02 00:00:00

abstract：:The uptake of amino acids into slices of adult and newborn mouse brain was studied in relation to Na+ flow. (1) The level of Na+ and K+ incubated slices of brain depends on the ionic composition of the incubation medium. The intracellular levels of Na+ in adult tissue are below, in fetal tissue above, Na+ levels in th...

journal_title：Brain research

authors： Lajtha A,Sershen H

更新日期：1975-02-14 00:00:00

abstract：:Detailed quantitative information on catecholamines and 5-hydroxytryptamine (serotonin) in the human thalamus is much needed because of increasing interest in norepinephrine and serotonin as modulators of thalamic behavioral state control and overall information processing. This study provides three-dimensional distri...

journal_title：Brain research

authors： Oke AF,Carver LA,Gouvion CM,Adams RN

更新日期：1997-07-18 00:00:00

abstract：:We have used magnetic resonance imaging (MRI) of the living rat brain to longitudinally analyze the ontogenesis of an ibotenic acid lesion targeted at the piriform cortex. The MRI data were systematically compared with data obtained from a battery of histopathological techniques, including Nissl stain, hematoxylin sta...

journal_title：Brain research

authors： Ben-Horin N,Hazvi S,Bendel P,Schul R

更新日期：1996-04-29 00:00:00

abstract：:Inoculation of the tail base of rats with Mycobacterium butyricum led to an arthritic swelling and inflammation of the limbs which displayed a hyperalgesia to noxious pressure: these effects peaked at 3 weeks postinoculation. In vitro autoradiography of coronal sections of rat brain was used for a parallel determinati...

journal_title：Brain research

authors： Millan MJ,Morris BJ,Colpaert FC,Herz A

更新日期：1987-07-28 00:00:00

abstract：:Bilateral quisqualic acid-induced lesions of the nucleus basalis magnocellularis (nbm) in rats disrupted the expression of latent inhibition, a phenomenon thought to be dependent upon selective attention processes. Since grafts of adrenal chromaffin cells to the cerebral cortex of nbm-lesioned rats have been shown to ...

journal_title：Brain research

authors： Welner SA,Rousse I,Rochford J

更新日期：1995-02-13 00:00:00

abstract：:We identified cell bodies of a pair of the cardio-inhibitory (CI) neurons in the first thoracic ganglion (TG1) of Bathynomus doederleini. Each of the cell bodies gives rise to a single axon, which runs into the contralateral hemiganglion of TG1 via the commissure and runs to the heart via the fourth root as CI axon. S...

journal_title：Brain research

authors： Tanaka K,Kuwasawa K

更新日期：1991-09-06 00:00:00

abstract：:Somatostatin neuronal perikarya and their processes, presumably dendrites, in the periventricular nucleus of the rat hypothalamus and terminals in the median eminence were observed by electron microscopic immunohistochemistry. Neuronal perikarya and processes contained immunoreactive dense granules (100-120 nm in diam...

journal_title：Brain research

authors： Ibata Y,Obata HL,Kubo S,Fukui K,Okamura H,Ishigami T,Imagawa K,Sin S

更新日期：1983-01-10 00:00:00

abstract：:Entopeduncular nucleus (EPN) cells which project to thalamic and non-thalamic sites were identified by antidromic discharge. Each population of cells, projecting to the ventral anterior nucleus of the thalamus (VA), centrum medianum (CM), the lateral habenula (LHB), and the pedunculopontine nucleus (PP), was distribut...

journal_title：Brain research

authors： Larsen KD,Sutin J

更新日期：1978-11-17 00:00:00

abstract：:Variables influencing decision-making in real settings, as in the case of voting decisions, are uncontrollable and in many times even unknown to the experimenter. In this case, the experimenter has to study the intention to decide (vote) as close as possible in time to the moment of the real decision (election day). H...

journal_title：Brain research

authors： da Rocha AF,Rocha FT,Burattini MN,Massad E

更新日期：2010-09-10 00:00:00

abstract：:Serotonin 1A receptor (5-HT(1A)R) agonists have emerged as valuable supplements to l-DOPA therapy, demonstrating that they can decrease side effects and enhance motor function in animal models of Parkinson's disease (PD) and human PD patients. The precise mechanism by which these receptors act remains unknown and ther...

journal_title：Brain research

authors： Dupre KB,Eskow KL,Negron G,Bishop C

更新日期：2007-07-16 00:00:00

abstract：:Visual spatial orienting of attention towards exogenous cues has been one of the attentional functions considered to be spared in ADHD. Here we present a design in which 60 (30 ADHD) children, age: 10.9±1.4, were asked to covertly orient their attention to one or two (out of four) cued locations, and search for a targ...

journal_title：Brain research

authors： Ortega R,López V,Carrasco X,Anllo-Vento L,Aboitiz F

更新日期：2013-02-01 00:00:00

abstract：:Intracerebroventricular (i.c.v.) administration of corticotropin-releasing factor (CRF) biphasically affects performance in tests of learning and memory. In the present study, we used CRF, urocortin (Ucn), a recently cloned CRF homologue, and CRF receptor antagonists, to determine which CRF receptor subtype(s) mediate...

journal_title：Brain research

authors： Zorrilla EP,Schulteis G,Ormsby A,Klaassen A,Ling N,McCarthy JR,Koob GF,De Souza EB

更新日期：2002-10-18 00:00:00

abstract：:Intracisternal administration of aluminum maltolate to rabbits produces a marked argyrophilic neurofibrillary degeneration (NFD) which is also immunoreactive for both phosphorylated and non-phosphorylated microtubule associated protein tau. Using tissue fixation in PBF, the monoclonal antibodies Tau-2 and AT8 stain th...

journal_title：Brain research

authors： Savory J,Huang Y,Herman MM,Reyes MR,Wills MR

更新日期：1995-01-16 00:00:00

abstract：:Stanniocalcin (STC-1), a 50 kDa glycoprotein hormone that regulates calcium/phosphate homeostasis in bony fish and mammals, has been shown to be expressed in central neurons and choroid plexus, and to exert a protective effect against hypercalcemic and hypoxic damage to neurons. Circumventricular organs are known to f...

journal_title：Brain research

authors： Ratkovic S,Wagner GF,Ciriello J

更新日期：2008-07-07 00:00:00

abstract：:The omega-3 fatty acids are essential dietary nutrients and one of their important roles is providing the fatty acid with 22 carbons and 6 double bonds known as docosahexaenoic acid (DHA) for nervous tissue growth and function. Inadequate intakes of omega-3 fatty acids decrease DHA and increase omega-6 fatty acids in ...

journal_title：Brain research

authors： Innis SM

更新日期：2008-10-27 00:00:00

abstract：:Intradentate administration of colchicine has been reported to affect the cholinergic muscarinic system in the hippocampus, causing a reduction in quinclidinylbenzilate binding sites and an increase in choline acetyltransferase activity. Since the cholinergic muscarinic system is coupled to the formation of inositolph...

journal_title：Brain research

authors： Tandon P,Harry GJ,Tilson HA

更新日期：1989-01-16 00:00:00

abstract：BACKGROUND:Inflammatory damage aggravates the cerebral ischemic pathological process and may pave a new way for treatment. Bicyclol has been proved to elicit a series of biologic effects through its anti-inflammatory property in treating hepatitis and hepatic ischemic/reperfusion injury. Whether this protective effect ...

journal_title：Brain research

authors： Zhang J,Fu B,Zhang X,Chen L,Zhang L,Zhao X,Bai X,Zhu C,Cui L,Wang L

更新日期：2013-08-28 00:00:00

abstract：:Following codepletion of endogenous serotonin (5-HT, greater than 90%) and thyrotropin-releasing hormone (TRH, 66%) by neonatal treatment with the serotonergic neurotoxin, 5,7-dihydroxytryptamine (DHT), a 33% (n = 12, P less than 0.01) increase in specific TRH receptor binding was observed in adult rat spinal cord (SC...

journal_title：Brain research

authors： Sharif NA,Towle AC,Burt DR,Mueller RA,Breese GR

更新日期：1989-02-20 00:00:00

abstract：:In the neocortex, fast excitatory synaptic transmission can typically be blocked by using excitatory amino acid (EAA) receptor antagonists. In recordings from layer II/III neocortical pyramidal neurons, we observed an evoked excitatory postsynaptic potential (EPSP) or current (EPSC) in the presence of EAA receptor ant...

journal_title：Brain research

authors： Chu ZG,Zhou FM,Hablitz JJ

更新日期：2000-12-29 00:00:00

abstract：:The role of plantar pressure sensation in controlling compensatory stepping was explored via hypothermic anesthesia of the foot soles, in 10 healthy young adults. Stepping reactions were evoked by unpredictable platform translation in forward, backward and lateral directions. The findings suggest three specific direct...

journal_title：Brain research

authors： Perry SD,McIlroy WE,Maki BE

更新日期：2000-09-22 00:00:00

abstract：:The response properties of neurons in the region of striate cortex subserving central retina (0 degrees-2 degrees) and in a region of representation of parafoveal retina (4 degrees-7 degrees) were studied in unanesthetized paralyzed macaque monkeys. Neurons sensitive to the orientation of the stimulus in the visual fi...

journal_title：Brain research

authors： Poggio GF,Baker FH,Mansfield RJ,Sillito A,Grigg P

更新日期：1975-12-12 00:00:00

abstract：:The distribution of cerebellar [3H]flunitrazepam binding sites was studied autoradiographically in Purkinje cell degeneration (pcd/pcd), weaver (wv/wv), staggerer (sg/sg) and reeler (rl/rl) mutant mice. In the normal 78-day-old C57BL/6J mouse cerebellum, the highest concentration of [3H]flunitrazepam binding sites was...

journal_title：Brain research

authors： Rotter A,Frostholm A

更新日期：1988-03-15 00:00:00

abstract：:This review provides a snapshot of the current ethical issues related to research with human brain organoids. The issues fall into the following main themes: research oversight; human biomaterials procurement and donor consent; translational delivery; animal research; and organoid consciousness and moral status. Each ...

journal_title：Brain research

authors： Hyun I,Scharf-Deering JC,Lunshof JE

更新日期：2020-04-01 00:00:00

abstract：:Carbonic anhydrase (CA) and cholinesterase (CE) histochemical staining of rabbit spinal nerve roots and dorsal root ganglia demonstrated that among the reactive myelinated axons, with minor exceptions, sensory axons were CA positive and CE negative whereas motor axons were CA negative and CE positive. The high specifi...

journal_title：Brain research

authors： Riley DA,Sanger JR,Matloub HS,Yousif NJ,Bain JL,Moore GH

更新日期：1988-06-21 00:00:00

abstract：:Opiates modulate pain perception at a number of different levels within the central nervous system and the importance of synergistic spinal and supraspinal influences have been well documented. In the present study we demonstrate synergistic interactions between the periaqueductal gray and locus coeruleus. Administere...

journal_title：Brain research

authors： Bodnar R,Paul D,Pasternak GW

更新日期：1991-09-06 00:00:00