Some cellular characteristics of somatostatin neurons and terminals in the periventricular nucleus of the rat hypothalamus and median eminence. Electron microscopic immunohistochemistry.

Abstract:

:Somatostatin neuronal perikarya and their processes, presumably dendrites, in the periventricular nucleus of the rat hypothalamus and terminals in the median eminence were observed by electron microscopic immunohistochemistry. Neuronal perikarya and processes contained immunoreactive dense granules (100-120 nm in diameter) and other cellular components such as polysomes, rER membranes occasionally showed high electron density. Few axo-somatic terminals were found on the somatostatin neurons, but we could detect a number of preterminal axons on immunoreactive processes, presumably dendrites. Therefore, we considered that somatostatin neurons receive mainly neuronal input through axo-dendritic synapses rather than through axo-somatic ones. In the somatostatin terminals in the external layer of the median eminence immunoreactivity was completely restricted on the granules.

journal_name

Brain Res

journal_title

Brain research

authors

Ibata Y,Obata HL,Kubo S,Fukui K,Okamura H,Ishigami T,Imagawa K,Sin S

doi

10.1016/0006-8993(83)91153-8

subject

Has Abstract

pub_date

1983-01-10 00:00:00

pages

291-5

issue

2

eissn

0006-8993

issn

1872-6240

pii

0006-8993(83)91153-8

journal_volume

258

pub_type

杂志文章
  • Administration of oral methylphenidate during adolescence prevents suppressive development of dopamine projections into prefrontal cortex and amygdala after an early pharmacological challenge in gerbils.

    abstract::The enduring effects of postweaning subchronic methylphenidate (MP) treatment and/or previous early preweaning methamphetamine (MA) application on dopamine (DA) fiber density were investigated in multiple cortical and subcortical areas of the gerbil brain. The study aimed to explore three questions: (1) is the develop...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2007.06.107

    authors: Grund T,Teuchert-Noodt G,Busche A,Neddens J,Brummelte S,Moll GH,Dawirs RR

    更新日期:2007-10-24 00:00:00

  • Inhibitory actions of taurocyamine, hypotaurine, homotaurine, taurine and GABA on spike discharges of Purkinje cells, and localization of sensitive sites, in guinea pig cerebellar slices.

    abstract::The effects of the possible metabolites of taurine--taurocyamine and hypotaurine--and of homotaurine on spike discharge frequency of guinea pig cerebellar Purkinje cells were investigated in comparison with taurine and GABA. Taurocyamine, hypotaurine and homotaurine all dose-dependently suppressed the spike frequency ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(81)90538-2

    authors: Okamoto K,Sakai Y

    更新日期:1981-02-16 00:00:00

  • Stability of cell size and nucleolar size in tangle-bearing neurons of the hippocampus in Alzheimer's disease.

    abstract::Samples of 14 brains of autopsied patients suffering from dementia of the Alzheimer type were examined. In Congo red-hemalum stained 14-microns-thick sections of the hippocampus 15 tangle-bearing and 25-30 unaffected nerve cells of area CA1 per case were measured for cell size and nucleolar size utilizing an interacti...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(89)90843-3

    authors: Gertz HJ,Schoknecht G,Krüger H,Cervos-Navarro J

    更新日期:1989-05-22 00:00:00

  • Electrical stimulation reveals relatively ineffective sural nerve projections to dorsal horn neurons in the cat.

    abstract::Electrical stimulation of the sural nerve (SN) revealed input from sural nerve afferents to L6 and L7 dorsal horn neurons that were not apparent using natural mechanical stimuli, especially in cells with variable latency responses to SN stimulation. Nearly all (31/32) cells that had reliable, fixed latency responses t...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(86)90816-4

    authors: Pubols LM,Foglesong ME,Vahle-Hinz C

    更新日期:1986-04-16 00:00:00

  • Macrolide antibiotics protect neurons in culture against the N-methyl-D-aspartate (NMDA) receptor-mediated toxicity of glutamate.

    abstract::The immunosuppressive macrolide FK-506 has been shown to protect neurons in culture against glutamate excitotoxicity. This effect was attributed to the binding of immunosuppressants to calcineurin-inhibiting immunophilins. We now report that also the non-immunosuppressive macrolide antibiotics protect neurons in cultu...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(93)90098-8

    authors: Manev H,Favaron M,Candeo P,Fadda E,Lipartiti M,Milani D

    更新日期:1993-10-08 00:00:00

  • Expression of c-fos protein by immunohistochemically identified oxytocin neurons in the rat hypothalamus upon osmotic stimulation.

    abstract::Double immunostaining for c-fos and oxytocin (OXY) was used to study the topography and time course of the metabolic activation of the hypothalamic oxytocinergic system upon osmotic stress in the male rat. Animals injected i.p. with hypertonic saline expressed c-fos-like immunoreactivity (FLI) in the paraventricular (...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(92)91342-c

    authors: Giovannelli L,Shiromani PJ,Jirikowski GF,Bloom FE

    更新日期:1992-08-14 00:00:00

  • Superior cervical ganglionectomy suppresses circadian corticotropic rhythms in male rats in the short term (5 days) and long term (10 days).

    abstract::Superior cervical ganglionectomy (SCGx) has drastic effects on numerous hormonal circadian rhythms and particularly on pineal melatonin secretion. We investigated the hormonal consequences of ablation of the superior cervical ganglion on the corticotropic circadian rhythms in the male rat. Plasma were obtained by samp...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(94)90237-2

    authors: Siaud P,Mekaouche M,Maurel D,Givalois L,Ixart G

    更新日期:1994-08-01 00:00:00

  • The association of catechol-O-methyltransferase genotype with the phenotype of women with eating disorders.

    abstract:OBJECTIVE:The modern brain imaging studies in patients with eating disorders have shown that neurotransmitting regulation differs distinctly from control groups. These disturbances have involved serotonin and dopamine system can be inherited and conditioned by genes. The aim of this work has been the analysis of associ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2009.10.035

    authors: Mikołajczyk E,Grzywacz A,Samochowiec J

    更新日期:2010-01-11 00:00:00

  • Entorhinal and prepiriform cortices of the European hedgehog. A histochemical and densitometric study based on a comparison between Timm's sulphide silver method and the selenium method.

    abstract::The Timm and selenium staining techniques, based on silver amplification of endogenous zinc, produce an electron-dense precipitate in boutons. The staining characteristics of the two methods were compared by examining two allocortical regions, prepiriform cortex and entorhinal cortex, in the brain of the European hedg...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(85)90361-0

    authors: Schwerdtfeger WK,Danscher G,Geiger H

    更新日期:1985-11-25 00:00:00

  • Passive electrical properties of motoneurons in aged cats following axotomy.

    abstract::The objective of this study was to determine whether the aging process influences the changes in the electrophysiological properties of motoneurons that occur as a consequence of axotomy. Accordingly, using intracellular recording and stimulating techniques, the basic electrical properties of control (unaxotomized) an...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(92)90594-y

    authors: Yamuy J,Engelhardt JK,Morales FR,Chase MH

    更新日期:1992-01-20 00:00:00

  • Isolation and characterisation of glutamate receptor antagonists from venoms of orb-web spiders.

    abstract::Two distinct families of low-molecular-weight toxins (argiotoxins) have been isolated from the venom of the orb-web spider. Argiope trifasciata. The toxins have been purified to homogeneity and characterised by spectroscopic, mass spectrometric and microchemical analysis. The major biologically active member of the fi...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(88)91098-0

    authors: Budd T,Clinton P,Dell A,Duce IR,Johnson SJ,Quicke DL,Taylor GW,Usherwood PN,Usoh G

    更新日期:1988-05-10 00:00:00

  • The organisation of spinal projecting brainstem neurons in an animal model of muscular dystrophy. A retrograde tracing study on mdx mutant mice.

    abstract::Previous studies we performed on the mdx mouse demonstrated marked central nervous system alterations in this model of human Duchenne muscular dystrophy, such as reduction in number and pathological changes of cortico-spinal neurons. Prompted by these findings we extended the survey of the mdx brain to the major brain...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(01)02108-4

    authors: Carretta D,Santarelli M,Vanni D,Carrai R,Sbriccoli A,Pinto F,Minciacchi D

    更新日期:2001-03-23 00:00:00

  • Altered activity patterns following neonatal 6-hydroxydopamine lesions to dopaminergic neurons: effect of SKF-38393.

    abstract::The effects of neonatal dopamine depletion on activity levels and locomotor patterns were tested in rats at 4 months of age. Measurements were taken using an activity pattern monitor. The lesioned group was significantly hypoactive in comparison to the control animals during the initial exposures to the monitor. Exami...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(94)91637-3

    authors: Moy SS,Breese GR,Eckerman DA

    更新日期:1994-05-09 00:00:00

  • Catecholamine synthesizing enzymes in the hypothalamus during the estrous cycle.

    abstract::The activities of tyrosine hydroxylase and dopamine-beta-hydroxylase were measured in the medial basal hypothalamus and remaining hyothalamic tissue of female rats at various times during diestrus 2, proestrus and estrus. Tyrosine hydroxylase activity in the medial basal hypothalamus was significantly lower at 12.00 h...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(80)90407-2

    authors: Carr LA,Voogt JL

    更新日期:1980-09-08 00:00:00

  • Effect of external acidosis on basal and ATP-evoked calcium influx in cultured astrocytes.

    abstract::The effect of lactic acidosis on calcium influx, accumulation and efflux was studied in primary cultures of neonatal cortical rat astrocytes. Treatment of cultures with 20 mM sodium lactate, pH 6.0, for 10-60 min resulted in a 35% reduction of 45Ca2+ influx. The decrease in calcium influx was pH dependent because a si...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(93)90371-s

    authors: Neary JT,Fu Q,Bender AS,Norenberg MD

    更新日期:1993-02-26 00:00:00

  • Determination of microdialysis extraction fraction of cocaine by the no net flux method under high, low, and zero steady-state cocaine concentrations in rats.

    abstract::The effect of different steady-state cocaine concentration maintenance on the microdialysis extraction fraction of cocaine (in situ recovery; Ed) in the medial prefrontal cortex (mPFC) was examined. Male, adult Sprague-Dawley rats anesthetized with chloral hydrate were used. All rats were randomly divided into three g...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(95)00456-z

    authors: Pan WH,Lee JC

    更新日期:1995-07-24 00:00:00

  • Contralaterally projecting lamina VIII interneurones in middle lumbar segments in the cat.

    abstract::Peripheral input to lamina VIII interneurones was investigated by using extracellular and/or intracellular records from them. The interneurones were located in the L4-L5 spinal segments and projected to contralateral motor nuclei in the L7 segment. They constituted a non-homogeneous population but their input from mus...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(90)91618-q

    authors: Jankowska E,Noga BR

    更新日期:1990-12-10 00:00:00

  • Separation of different interictal discharge patterns in acute experimentally induced epileptic foci of the rat in vivo.

    abstract::Epileptic discharge patterns in an acute experimental model of epilepsy were analyzed. Epileptic foci were induced by epicortical application of penicillin on the rat motor cortex in vivo. Patterns with regular 1/s discharges, patterns with irregular discharges of about 0.5/s as well as compound patterns comprising di...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(93)90221-8

    authors: Dorn T,Witte OW

    更新日期:1993-07-09 00:00:00

  • Anatomical, physiological and biochemical studies on the cerebellum from mutant mice. III. Protein differences associated with the weaver, staggerer and nervous mutations.

    abstract::The protein composition of subcellular fractions of the cerebella of normal and weaver, staggerer and nervous mutant mice and of X-irradiated rats are studied by polyacrylamide gel electrophoresis in sodium dodecyl sulphate. The patterns observed are compared with those of granular and Purkinje cells purified from rat...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(76)90800-3

    authors: Mallet J,Huchet M,Pougeois R,Changeux JP

    更新日期:1976-02-20 00:00:00

  • Inhibition by sodium valproate of the arginine vasopressin and adrenocorticotropin responses to angiotensin II in normal men.

    abstract::The present study was carried out in order to determine whether angiotensin II (ANG II) exerts its stimulatory effect on plasma concentration of arginine vasopressin (AVP) and adrenocorticotrophic hormone (ACTH) by interacting with a (gamma-aminobutyric acid) GABAergic pathway. For this purpose, the effect of the GABA...

    journal_title:Brain research

    pub_type: 临床试验,杂志文章

    doi:10.1016/0006-8993(89)90100-5

    authors: Coiro V,Chiodera P

    更新日期:1989-07-03 00:00:00

  • Visual discrimination learning impairments produced by combined transections of the anterior temporal stem, amygdala and fornix in marmoset monkeys.

    abstract::Marmoset monkeys (Callithrix jacchus) with bilateral transections of the anterior temporal stem, amygdala and fornix were unable to relearn a 2-choice object discrimination first learnt prior to surgery, and were very severely impaired at relearning a concurrent object discrimination task which they had learnt and rel...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(00)02998-x

    authors: Maclean CJ,Gaffan D,Baker HF,Ridley RM

    更新日期:2001-01-05 00:00:00

  • The dopamine agonist pramipexole scavenges hydroxyl free radicals induced by striatal application of 6-hydroxydopamine in rats: an in vivo microdialysis study.

    abstract::Hydroxyl free radical production seems to play an important role in the pathogenesis of Parkinson's disease. In the present study, we investigated the dopamine agonists pramipexole and pergolide as well as the nitrone compound S-PBN (N-tert-butyl-alpha-(2-sulfophenyl)nitrone) to reduce hydroxyl radical formation. Micr...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(00)02929-2

    authors: Ferger B,Teismann P,Mierau J

    更新日期:2000-11-17 00:00:00

  • Mast cells populations fluctuate along the spinal dura mater of the developing rat.

    abstract::The present study reveals developmental changes in the number, the phenotype and the distribution pattern of mast cells (MCs) along the cervical, the thoracic and the lumbar parts of the spinal dura mater. Postnatal infiltration of spinal dura by MCs does not appear to follow a sequential developmental pattern and men...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2008.05.057

    authors: Michaloudi H,Batzios C,Chiotelli M,Grivas I,Papadopoulos GC

    更新日期:2008-08-21 00:00:00

  • Substance P excites neurons in the gustatory zone of the rat nucleus tractus solitarius.

    abstract::Whole-cell patch recordings of neurons in the rostral (gustatory) nucleus tractus solitarius (rNTS) were performed in a brain slice preparation from rat medulla. Neural responses to brief applications (10-45 s) of substance P (SP), via a constant superfusion apparatus, were recorded. SP transiently depolarized 80 of 1...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(93)91603-p

    authors: King MS,Wang L,Bradley RM

    更新日期:1993-08-13 00:00:00

  • Analysis of protein levels and synthesis after learning in the split-brain pigeon.

    abstract::A series of experiments were performed to study the effects of learning upon proteins in the split-brain pigeon. With this preparation, one side of the brain was trained in a color discrimination task while the other side served as a naive control. Proteins from both sides of the brain were separated by one- and two-d...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(80)90349-2

    authors: Deutsch DG,Schechter N,Brecha N,Quitschke W,Schulman P,Cane M,Gazzaniga MS,Simpson MV

    更新日期:1980-09-29 00:00:00

  • Cerebral protein synthesis alterations in response to acute and chronic immobilization stress in the rat.

    abstract::The quantitative autoradiographic method with L-(35S)methionine was used to determine the effects of 1-acute (4h) and 2-chronic (14 days) immobilization stress followed by one week of recovery. Acute stress induced a significant decrease in methionine incorporation into proteins in 17 of the 35 brain structures examin...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(95)00046-s

    authors: Giaume M,Grange E,Baubet V,Gay N,Sermet E,Sarda N,Bobillier P

    更新日期:1995-03-27 00:00:00

  • Axonal growth and glial migration from co-cultured hippocampal and septal slices into fibrin-fibronectin-containing matrix of peripheral regeneration chambers: a light and electron microscope study.

    abstract::In order to investigate whether a fibrin-fibronectin-containing matrix of a peripheral regeneration chamber could promote the growth of central nervous system neurons, hippocampal and septal slices were co-cultured in the presence of this acellular substrate. In introducing the peripheral matrix into a 2-mm-long tube ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(91)90506-q

    authors: Knoops B,Hubert I,Hauw JJ,van den Bosch de Aguilar P

    更新日期:1991-02-01 00:00:00

  • Nociceptive responses of trigeminal neurons in SII-7b cortex of awake monkeys.

    abstract::A cluster of trigeminal nociceptive neurons was located in the lateral sulcus on the upper bank of the frontoparietal operculum in a region bordering between cortical areas SII and 7b. These neurons were isolated in cortical cell layers IV and V-VI. All nociceptive neurons responded exclusively to noxious mechanical s...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(89)90375-2

    authors: Dong WK,Salonen LD,Kawakami Y,Shiwaku T,Kaukoranta EM,Martin RF

    更新日期:1989-04-10 00:00:00

  • Galectin-3 mediates post-ischemic tissue remodeling.

    abstract::Galectin-3 (Gal-3) is a member of a class of carbohydrate-binding proteins and plays a role in a number of cellular functions such as cell proliferation, angiogenesis and differentiation. We observed an up-regulated expression of Gal-3 in the ischemic brain following transient middle cerebral artery occlusion in rats....

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2009.06.073

    authors: Yan YP,Lang BT,Vemuganti R,Dempsey RJ

    更新日期:2009-09-08 00:00:00

  • Activity of cat locus coeruleus noradrenergic neurons during the defense reaction.

    abstract::The single-unit activity of locus coeruleus noradrenergic (LC-NE) neurons was recorded in freely moving cats during naturally induced defense reactions. Defense reactions, consisting of arched back, piloerection, flattened ears and mydriasis, were elicited by exposing the cat either to a dog, or to a cat displaying ag...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(90)90773-5

    authors: Levine ES,Litto WJ,Jacobs BL

    更新日期:1990-10-29 00:00:00