Abstract：
:Epileptic discharge patterns in an acute experimental model of epilepsy were analyzed. Epileptic foci were induced by epicortical application of penicillin on the rat motor cortex in vivo. Patterns with regular 1/s discharges, patterns with irregular discharges of about 0.5/s as well as compound patterns comprising discharges with intervals of about 300 ms could be differentiated by means of interval histograms and autocorrelation functions. These patterns occurred in an ordered sequence indicating that the different rhythms are activated by a progressive enlargement of the focus and duration of focal activity. The experiments suggest that different interictal discharge patterns can occur within the same brain regions and are not specific for a certain etiology; instead they seem to represent 'resonance' frequencies characteristic for the brain tissue which are disclosed under pathophysiological conditions.
journal_name
Brain Resjournal_title
Brain researchauthors
Dorn T,Witte OWdoi
10.1016/0006-8993(93)90221-8subject
Has Abstractpub_date
1993-07-09 00:00:00pages
303-6issue
1-2eissn
0006-8993issn
1872-6240pii
0006-8993(93)90221-8journal_volume
616pub_type
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