Localization of Mn-superoxide dismutase (Mn-SOD) in cholinergic and somatostatin-containing neurons in the rat neostriatum.

abstract：:In the present study, we used an immunocytochemical technique at the electron microscopic level to determine if there are changes in the glutamate and GABA neurotransmitter content of the hippocampus of genetic absence epilepsy rats from Strasbourg (GAERS). We also investigated if there was mossy fiber reorganization....

journal_title：Brain research

authors： Sirvanci S,Meshul CK,Onat F,San T

更新日期：2003-10-24 00:00:00

abstract：:We used in situ hybridization and immunocytochemistry to investigate the presence of GABA in neurons that express the type 3 serotonin receptor (5-HT3R). Quantitative analysis indicated that more than 90% of 5-HT3R expressing cells are GABAergic in the neocortex and hippocampus. The co-existence of 5-HT3R and GABA in ...

journal_title：Brain research

authors： Morales M,Battenberg E,de Lecea L,Bloom FE

更新日期：1996-08-26 00:00:00

abstract：:Kallikrein hydrolyzes various biologically active peptides, other than kininogens, such as vasoactive intestinal polypeptide (VIP), in vitro. Since kallikrein and VIP have been immunohistochemically shown to be present in the perivascular areas of the pineal gland, this study was designed to determine their topographi...

journal_title：Brain research

authors： Kudo M,Yamazaki I,Suzuki T,Ebihara Y,Iwadate H,Kizuki K

更新日期：1998-06-29 00:00:00

abstract：:The effects of exo- and endogenous cGMP on the resting activity (RA) of afferent crista fibers were studied in isolated preparations of the statocysts of the cuttlefish Sepia officinalis and the squid Sepioteuthis lessoniana. Bath application of the membrane-permeable cGMP analogs 8-bromo-cGMP (B-cGMP) and N(2),2'-o-d...

journal_title：Brain research

authors： Tu Y,Budelmann BU

更新日期：2000-10-13 00:00:00

abstract：:Intravenous administration of lipopolysaccharide (LPS) (0.9 mg/kg) has been shown to induce ischemic tolerance in spontaneously hypertensive rats (SHR). TNF-alpha is believed to play a crucial role in preconditioning as its inhibition with TNF-alpha-binding protein abolished tolerance. Our recent studies (Liu et al., ...

journal_title：Brain research

authors： Zimmermann C,Ginis I,Furuya K,Klimanis D,Ruetzler C,Spatz M,Hallenbeck JM

更新日期：2001-03-23 00:00:00

abstract：:The innervation of the tensor tympani muscle of the middle ear in Macaca fascicularis (cynomolgus monkey) was studied using the horseradish peroxidase (HRP) neural tracing technique. A compact column of small trigeminal motoneurons was labeled ipsilaterally following intramuscular application of HRP to the tensor tymp...

journal_title：Brain research

authors： Gannon PJ,Eden AR

更新日期：1987-02-24 00:00:00

abstract：:A major role of tooth receptors in signaling overt or impending tissue damage (nociception) has been previously established by substantial evidence from mechanical, thermal and chemical stimulation of exposed dentin. We report evidence showing that some intradental receptors in canine teeth of the cat detect mechanica...

journal_title：Brain research

authors： Dong WK,Chudler EH,Martin RF

更新日期：1985-05-20 00:00:00

abstract：:Transplantation of fetal substantia nigra into the brain can alleviate some of the manifestations of animal models of Parkinson's disease. The purpose of the present experiment was to determine the optimal embryonic donor age for solid tissue substantia nigra grafts. Rats with unilateral substantia nigra lesions were ...

journal_title：Brain research

authors： Simonds GR,Freed WJ

更新日期：1990-10-15 00:00:00

abstract：:We examined the electrophysiological properties of cholinergic and non-cholinergic neurons in the medial septum-diagonal band complex (MSDB) of the rat in the in vitro slice preparation. Cells were identified electrophysiologically, filled with Lucifer yellow, fixed and processed for immunohistochemistry with fluoresc...

journal_title：Brain research

authors： Markram H,Segal M

更新日期：1990-04-09 00:00:00

abstract：:The purpose of this study was to investigate the cannabinoid and opioid mediated regulation on the effects of central Delta(9)-tetrahydrocannabinol (Delta(9)-THC) administration on hypothalamus-pituitary-adrenal (HPA) axis activity in the male rat. Intracerebroventricular (i.c.v.) administration of delta(9)-THC (25, 5...

journal_title：Brain research

authors： Manzanares J,Corchero J,Fuentes JA

更新日期：1999-08-21 00:00:00

abstract：:In vivo proton magnetic resonance spectroscopy was used to investigate intracerebral phenylalanine (Phe) concentrations in nine patients with classical phenylketonuria (PKU). The study included serial examinations (n = 31; plasma Phe levels: 0.47-2.24 mmol/l) of patients either receiving a Phe-restricted diet (200 mg ...

journal_title：Brain research

authors： Möller HE,Weglage J,Wiedermann D,Vermathen P,Bick U,Ullrich K

更新日期：1997-12-19 00:00:00

abstract：:We investigated c-Met expression in cultured astrocytes and their regulation by cytokines. Immunocytochemistry revealed that c-Met was expressed in cultured astrocytes. Western blotting revealed that acidic and basic fibroblast growth factor (FGF) enhanced and hepatocyte growth factor (HGF) reduced c-Met expression. R...

journal_title：Brain research

authors： Shimazaki K,Yoshida K,Hirose Y,Ishimori H,Katayama M,Kawase T

更新日期：2003-02-07 00:00:00

abstract：:Effects of hypothalamic stimulation (HS) were studied in intracellular recordings obtained from 125 neurons of the motor cortex (MC). HS that was effective in reinforcing bar-press behavior, i.e. satisfactory for intracranial self-stimulation (ICSS), evoked short-latency (less than 3 ms) activation of these cortical n...

journal_title：Brain research

authors： Aou S,Oomura Y,Woody CD,Nishino H

更新日期：1988-01-26 00:00:00

abstract：:Reduced glutathione (GSH) plays an important role in cellular protection against damage from free radicals and other electrophiles. GSH in the rat central nervous system was quantitatively analyzed. In adult brain, tissue from the cerebellum and cerebrum had higher GSH levels than that from the brainstem and spinal co...

journal_title：Brain research

authors： Kudo H,Kokunai T,Kondoh T,Tamaki N,Matsumoto S

更新日期：1990-03-19 00:00:00

abstract：:Individuals are found to have better recall for self-referent information than other types of information. However, attribution research has shown that self-reference is highly correlated with emotional valence. The present study attempted to identify and separate the processing of self-reference and emotional valence...

journal_title：Brain research

authors： Watson LA,Dritschel B,Obonsawin MC,Jentzsch I

更新日期：2007-06-04 00:00:00

abstract：:A major function of the dopamine in the striatum is to control the activity of its efferent systems which contain primarily GABAergic neurons. Direct intracerebral injections of haloperidol into the corpus striatum impaired the performance of rats trained to depress a lever in a sensitive reaction time task. Rats were...

journal_title：Brain research

authors： Amalric M,Koob GF

更新日期：1989-04-03 00:00:00

abstract：:Using in vivo microdialysis, we examined the ability of choline (Ch) chloride (120 mg/kg i.p.) to amplify basal and stimulated acetylcholine (ACh) release from rat striatum in the presence of high (10(-5) M) and low (5 x 10(-8) M) neostigmine concentration. High concentrations might suppress ACh release, and thus Ch d...

journal_title：Brain research

authors： Marshall DL,Wurtman RJ

更新日期：1993-12-03 00:00:00

abstract：:Visuomotor behavior and pattern discrimination were studied in a group of cats raised with one eye closed by eyelid suturing 7-10 days after birth. At the age of 8-10 months the animals were forced to use their deprived eye by reversal of eye closure (closing the normal eye and opening the deprived one). Visuomotor be...

journal_title：Brain research

authors： Hof-Van Duin JV

更新日期：1976-07-30 00:00:00

abstract：:The immunocytochemical localization of the enzyme choline acetyltransferase (ChAT) was examined in the guinea pig organ of Corti to determine if both lateral and medial systems of efferents would show immunoreactive labeling for this specific enzyme marker of cholinergic neurons. Cochleae were also examined after lesi...

journal_title：Brain research

authors： Altschuler RA,Kachar B,Rubio JA,Parakkal MH,Fex J

更新日期：1985-07-08 00:00:00

abstract：:Locally applied ciliary neurotrophic factor (CNTF) has a powerful effect on retrograde axonal reaction following facial nerve crush in neonatal rats. We examined whether it also exerts a strong effect on retrograde axonal reaction in young adult rats when administered subcutaneously. The dose was 1 mg/kg body weight, ...

journal_title：Brain research

authors： Ulenkate HJ,Gispen WH,Jennekens FG

更新日期：1996-04-22 00:00:00

abstract：:Medial basal hypothalamic (MBH) 5 alpha-reductase activity was significantly blocked with a known inhibitor, Proscar (Finasteride), in pregnant rats while their open-field behavior was quantified during the last week of pregnancy. In control animals, open-field behavior significantly decreased (in a stair-step fashion...

journal_title：Brain research

authors： Lephart ED,Ladle DR,Jacobson NA,Rhees RW

更新日期：1996-11-11 00:00:00

abstract：:Pars interpolaris of the spinal trigeminal nucleus of kittens has been studied with the electron microscope at birth and at several subsequent ages during the first month of life. Attention has been given to ultrastructural maturational changes that occur in this neuropil, especially events in synaptogenesis. The resu...

journal_title：Brain research

authors： Dunn RC,Westrum LE

更新日期：1978-03-31 00:00:00

abstract：:The effects of substantia nigra (SN) stimulation on the activity of the nucleus ventralis lateralis of the thalamus (VL) have been studied. The VL cells were identified as relay or non-relay cells among the cerebellothalamocortical pathway on the basis of orthodromical activation from the cerebellum and antidromical a...

journal_title：Brain research

authors： Deniau JM,Lackner D,Feger J

更新日期：1978-04-21 00:00:00

abstract：:The present studies examined the hypothesis that the N-methyl-D-aspartate (NMDA) receptor-nitric oxide (NO) pathway might be involved in the acute and chronic actions of delta 9-tetrahydrocannabinol (THC). The ability of dizocilpine (MK-801), a competitive NMDA receptor antagonist and NG-monomethyl-L-arginine (L-NMMA)...

journal_title：Brain research

authors： Thorat SN,Bhargava HN

更新日期：1994-12-19 00:00:00

abstract：:Bradykinin is known to rapidly elevate intracellular calcium leading to secretion of neurotransmitters and short term activation of tyrosine hydroxylase (TH). In this study we examined the effect of bradykinin on mRNA levels of two catecholamine biosynthetic enzymes. Treatment of PC12 cells with 1 microM bradykinin fo...

journal_title：Brain research

authors： Gebreyesus K,Kilbourne EJ,Sabban EL

更新日期：1993-04-16 00:00:00

abstract：:Long-term potentiation (LTP) can be initiated in CA1, but not in the dentate, region of slices from rats with bilateral subcortical deafferentation at 8 week survival time. At about one week survival time, LTP is present in the CA1 region of all and also in the dentate of about 50% of slices. The results suggest that ...

journal_title：Brain research

authors： Czéh G,Horváth Z,Czopf J

更新日期：1990-06-04 00:00:00

abstract：:The immediate-early gene egr-1 has been shown to have an increased expression during long-term potentiation (LTP). High frequency electrical stimulation induces an increase in such expression in the dorsal horn of the spinal cord. However, evidence demonstrating the activation of this gene in the spinal cord and its r...

journal_title：Brain research

authors： Nunes AC,Duarte RB,Sousa TB,dos Santos JR,Freire MA,Costa MS

更新日期：2010-07-23 00:00:00

abstract：:The binding of [3H]flunitrazepam and [3H]Ro5-4864 to crude homogenates of amygdala-kindled and 'yoked' control rat brains was evaluated in subjects sacrificed 60 days after the sixth generalized convulsion. Decreases in the Bmax for [3H]flunitrazepam binding to 'central-type' benzodiazepine receptors were observed in ...

journal_title：Brain research

authors： Burnham WM,Niznik HB,Okazaki MM,Kish SJ

更新日期：1983-11-21 00:00:00

abstract：:The horizontal and vertical vestibulo ocular reflex (VOR) of head tilted (het) mutant mice was compared to C57BL/6 controls. Eye movements were recorded in darkness using a temporarily attached search coil. Contributions of semicircular canal versus otolith organ signals were investigated by providing a canal only (ve...

journal_title：Brain research

authors： Harrod CG,Baker JF

更新日期：2003-05-16 00:00:00

abstract：:Partial, unilateral olfactory nerve section was performed in mice, and the behavior of the olfactory marker protein (OMP) studied, after this experimental manipulation, with the peroxidase--antiperoxidase method. The protein, which in normal mice is present only in mature olfactory sensory neurons, after unilateral le...

journal_title：Brain research

authors： Monti Graziadei GA,Graziadei PP

更新日期：1981-03-30 00:00:00